Results 11 to 20 of about 1,082,353 (268)
ABSTRACTIn 2014, WHO reported approximately 9.6 million new cases of tuberculosis (TB) in the world, more than half of which are contributed by developing countries in Asia and Africa. Lack of modern diagnostic tools, underreporting of the new cases and underutilization of directly observed therapy (DOT) remain a concern in developing countries ...
Mehta, Jay B., Dutt, Asim K.
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Chronic hepatitis B virus (CHB) infection remains a major global public health issue for which there is still lacking effective curative treatment. Interferon-α (IFN-α) and its pegylated form have been approved as an anti-HBV drug with the advantage of ...
Jiayi Wang +5 more
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Host Ranges of R Factors [PDF]
SUMMARY: All R factors so far described can be transmitted to Escherichia coli. F-like R factors are transmissible to the Proteus group but not to the Pseudomonadaceae. Among fi - R factors, I-like plasmids are not transferable to Proteus although they mediate conjugation, allowing transfer of other plasmids to this group. They are not transmissible to
N, Datta, R W, Hedges
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CRISPR-Cas9-Based Technology for Studying Enteric Virus Infection
Enteric viruses, including numerous viruses that initiate infection in enteric canal, are recognized as important agents that cause wide spectrum of illnesses in humans, depending on the virus type.
Junki Hirano +2 more
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Targeting Host Innate and Adaptive Immunity to Achieve the Functional Cure of Chronic Hepatitis B
Despite the availability of an effective preventive vaccine for hepatitis B virus (HBV) for over 38 years, chronic HBV (CHB) infection remains a global health burden with around 257 million patients. The ideal treatment goal for CHB infection would be to
Sayeh Ezzikouri +4 more
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Host Components Contributing to Respiratory Syncytial Virus Pathogenesis
Respiratory syncytial virus (RSV) is the most prevalent viral etiological agent of acute respiratory tract infection. Although RSV affects people of all ages, the disease is more severe in infants and causes significant morbidity and hospitalization in ...
Jonatan J. Carvajal +7 more
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Host Factors in Coronavirus Replication [PDF]
Coronaviruses are pathogens with a serious impact on human and animal health. They mostly cause enteric or respiratory disease, which can be severe and life threatening, e.g., in the case of the zoonotic coronaviruses causing severe acute respiratory syndrome (SARS) and Middle East Respiratory Syndrome (MERS) in humans.
de Wilde, Adriaan H. +3 more
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Advanced Molecular Surveillance of Hepatitis C Virus
Hepatitis C virus (HCV) infection is an important public health problem worldwide. HCV exploits complex molecular mechanisms, which result in a high degree of intrahost genetic heterogeneity. This high degree of variability represents a challenge for the
Livia Maria Gonçalves Rossi +2 more
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Unbridled Integrons: A Matter of Host Factors [PDF]
Integrons are powerful recombination systems found in bacteria, which act as platforms capable of capturing, stockpiling, excising and reordering mobile elements called cassettes. These dynamic genetic machineries confer a very high potential of adaptation to their host and have quickly found themselves at the forefront of antibiotic resistance ...
Richard, Egill +3 more
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Introduction: Host factors affecting pin site infections were selected by The Pin site Consensus Group, using a modified Delphi approach, to be one of the top 10 priorities to investigate how to reduce rates of pin site infections, improve clinical ...
Marie Fridberg +3 more
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