Results 11 to 20 of about 9,445,813 (266)

Research progress on the role of host factors in Chikungunya virus infection and intervention strategies [PDF]

Virulence
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus causing acute fever, rashes, and even acute or chronic arthralgia/arthritis. With its expanding global distribution, CHIKV represents a significant public health threat, yet no specific antivirals ...
Yibo Chen, Ke Zhang, Zhongtian Qi, Cuiling Ding   +3 more
doaj   +2 more sources

Retroanalytical Study of Epidemiological Factors of Rhinosporidiosis

International Archives of Otorhinolaryngology, 2021
Introduction Rhinosporidiosis is a granulomatous disease of humans and animals that is caused by Rhinosporidium Seeberi. This disease is endemic in certain states of India, like Chhattisgarh, Tamil Nadu, Kerala, Orissa, and eastern Madhya Pradesh.
Sairah Mathew, Ripu Daman Arora, Neel Prabha, Payal Kamble, Satish Suresh Satpute, Nitin M. Nagarkar   +5 more
doaj   +1 more source

Receptors for Respiratory Syncytial Virus Infection and Host Factors Regulating the Life Cycle of Respiratory Syncytial Virus

Frontiers in Cellular and Infection Microbiology, 2022
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections and responsible for a large proportion of mortality in children and the elderly. There are no licensed vaccines available to date.
Ziheng Feng, Ziheng Feng, Lili Xu, Lili Xu, Zhengde Xie, Zhengde Xie   +5 more
doaj   +1 more source

The accessible promoter-mediated supplementary effect of host factors provides new insight into the tropism of SARS-CoV-2

Molecular Therapy: Nucleic Acids, 2022
In the past year, the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in the worldwide coronavirus disease 2019 (COVID-19) pandemic. Yet our understanding of the SARS-CoV-2 tropism mechanism is still insufficient. In
Guifang Du, Xiang Xu, Junting Wang, Xuejun Wang, Yang Ding, Fei Li, Yu Sun, Huan Tao, Yawen Luo, Hao Li, Xiaochen Bo, Hebing Chen   +11 more
doaj   +1 more source

Targeting Host PIM Protein Kinases Reduces Mayaro Virus Replication

Viruses, 2022
Mayaro virus (MAYV) manipulates cell machinery to successfully replicate. Thus, identifying host proteins implicated in MAYV replication represents an opportunity to discover potential antiviral targets.
Madelaine Sugasti-Salazar, Dalkiria Campos, Patricia Valdés-Torres, Paola Elaine Galán-Jurado, José González-Santamaría   +4 more
doaj   +1 more source

Host Components That Modulate the Disease Caused by hMPV

Viruses, 2021
Human metapneumovirus (hMPV) is one of the main pathogens responsible for acute respiratory infections in children up to 5 years of age, contributing substantially to health burden.
Nicolás M. S. Gálvez, Catalina A. Andrade, Gaspar A. Pacheco, Jorge A. Soto, Vicente Stranger, Thomas Rivera, Abel E. Vásquez, Alexis M. Kalergis   +7 more
doaj   +1 more source

Tissue Proteases and Immune Responses: Influencing Factors of COVID-19 Severity and Mortality

Pathogens, 2020
The coronavirus disease 19 (COVID-19) is caused by the highly transmissible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has affected the global population despite socioeconomic status and amazed surveillance agencies for its ...
Natália Mulinari Turin de Oliveira, Isabella Fernandes da Silva Figueiredo, Liziane Cristine Malaquias da Silva, Karien Sauruk da Silva, Laryssa Regis Bueno, Bruna Barbosa da Luz, Cláudia Rita Corso, Maria Fernanda Paula Werner, Elizabeth Soares Fernandes, Daniele Maria-Ferreira   +9 more
doaj   +1 more source

The association of host genes with specific sexually transmitted infections

Frontiers in Reproductive Health, 2023
Sexually transmitted infections (STIs) are hazardous to human health worldwide. STIs have a direct influence on sexual and reproductive health and can increase the chances of HIV. Globally, more than 1 million STIs are acquired every day and the majority
Qhama Bovungana, Thilona Arumugam, Veron Ramsuran, Veron Ramsuran   +3 more
doaj   +1 more source

Host Factors Affect the Gut Microbiome More Significantly than Diet Shift

Microorganisms, 2021
The determining factors of the composition of the gut microbiome are one of the main interests in current science. In this work, we compared the effect of diet shift (DS) from heavily relying on meatatarian diets to vegetarian diets and physical exercise
Enkhchimeg Lkhagva, Hea-Jong Chung, Ji-Seon Ahn, Seong-Tshool Hong   +3 more
doaj   +1 more source

Suppression of Interferon-α Treatment Response by Host Negative Factors in Hepatitis B Virus Infection

Frontiers in Medicine, 2021
Chronic hepatitis B virus (CHB) infection remains a major global public health issue for which there is still lacking effective curative treatment. Interferon-α (IFN-α) and its pegylated form have been approved as an anti-HBV drug with the advantage of ...
Jiayi Wang, Jiayi Wang, Lingyao Du, Lingyao Du, Hong Tang, Hong Tang   +5 more
doaj   +1 more source