Results 81 to 90 of about 9,445,813 (266)

PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication

open access: yesmBio
Porcine epidemic diarrhea virus (PEDV) requires complete dependence on the metabolic system of the host cell to complete its life cycle. There is a strong link between efficient viral replication and cellular lipid synthesis.
Xiaojie Shi   +5 more
doaj   +1 more source

Glochidia ecology in wild fish populations and laboratory determination of competent host fishes for an endemic freshwater mussel of south-western Australia [PDF]

open access: yes, 2012
Glochidia (parasitic larvae) of freshwater mussels generally require a fish as a host. Westralunio carteri Iredale, 1934 (Bivalvia : Hyriidae), the only freshwater mussel found in south-western Australia, was listed as Vulnerable, but recently changed to
Morgan, David L   +9 more
core   +1 more source

Illustration of the WNV transmission cycle and major known climate sensitive factors affecting transmission through the vector-host-pathogen nexus.

open access: yes, 2023
Illustration of the WNV transmission cycle and major known climate sensitive factors affecting transmission through the vector-host-pathogen nexus.
Joacim Rocklöv (296647)   +2 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Susceptibility Genes to Plant Viruses

open access: yesViruses, 2018
Plant viruses use cellular factors and resources to replicate and move. Plants respond to viral infection by several mechanisms, including innate immunity, autophagy, and gene silencing, that viruses must evade or suppress.
Hernan Garcia-Ruiz
doaj   +1 more source

Foreign Direct Investment, Host Country Factors and Economic Growth [PDF]

open access: yes
This paper analyses how the levels of economic development, human capital, financial development and the qualities of the economic and political environments in host countries simultaneously affects the impact of aggregate inflows of Foreign Direct ...
Edna Maeyen Solomon
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Genome-Wide Identification of Host Genes Required for Toxicity of Bacterial Cytolethal Distending Toxin in a Yeast Model

open access: yesFrontiers in Microbiology, 2019
BackgroundAggregatibacter actinomycetemcomitans, a periodontal pathogen, secretes a cytolethal distending toxin (AaCDT) that causes host cell cycle arrest and cell death.
Siriyod Denmongkholchai   +11 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus

open access: yesMedComm
Chikungunya virus (CHIKV) is a mosquito‐borne alphavirus that is primarily known for causing severe joint and muscle symptoms, but its pathological effects have extended beyond these tissues. In this study, we conducted a comprehensive proteomic analysis
Dongdong Lin   +17 more
doaj   +1 more source

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