Results 11 to 20 of about 640,203 (218)

Vivax malaria in Duffy-negative patients shows invariably low asexual parasitaemia: implication towards malaria control in Ethiopia

Malaria Journal, 2022
Background The increase in detections of Plasmodium vivax infection in Duffy-negative individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy Binding Protein-Duffy antigen receptor for chemokines (PvDBP-DARC) pathway used by
Andargie Abate, Isabelle Bouyssou, Solenne Mabilotte, Cecile Doderer-Lang, Laurent Dembele, Didier Menard, Lemu Golassa   +6 more
doaj   +1 more source

MatGel: A MATLAB program for quantitative analysis of 2D polyacrylamide electrophoresis (2D-PAGE) protein gel images

MethodsX, 2022
Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) is widely used in proteomics studies. Hundreds of proteins extracted from a biological sample can be separated and visualized on a 2D-PAGE gel.
Alka Tiwari, W. Paul Williams, Xueyan Shan   +2 more
doaj   +1 more source

A Histological Study of Aspergillus flavus Colonization of Wound Inoculated Maize Kernels of Resistant and Susceptible Maize Hybrids in the Field

Frontiers in Microbiology, 2018
Aspergillus flavus colonization in developing kernels of maize single-cross hybrids resistant (Mp313E × Mp717) and susceptible (GA209 × T173) to aflatoxin accumulation was determined in the field over three growing seasons (2012–2014).
Gary L. Windham, William P. Williams, J. E. Mylroie, Cedric X. Reid, Erika D. Womack   +4 more
doaj   +1 more source

Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination

Toxins, 2018
Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using genetic mapping, genomics, transcriptomics and/or proteomics studies.
Leigh K. Hawkins, Marilyn L. Warburton, Juliet D. Tang, John Tomashek, Dafne Alves Oliveira, Oluwaseun F. Ogunola, J. Spencer Smith, W. Paul Williams   +7 more
doaj   +1 more source

Aflatoxin Accumulation in a Maize Diallel Cross

Agriculture, 2015
Aflatoxins, produced by the fungus Aspergillus flavus, occur naturally in maize. Contamination of maize grain with aflatoxin is a major food and feed safety problem and greatly reduces the value of the grain.
W. Paul Williams, Gary L. Windham
doaj   +1 more source

Comparison of Two Inoculation Methods for Evaluating Maize for Resistance to Aspergillus flavus Infection and Aflatoxin Accumulation

International Journal of Agronomy, 2013
Aflatoxin, the most potent carcinogen found in nature, is produced by the fungus Aspergillus flavus and occurs naturally in maize, Zea mays L. Growing maize hybrids with genetic resistance to aflatoxin contamination are generally considered a highly ...
W. Paul Williams, Michael N. Alpe, Gary L. Windham, Seval Ozkan, J. Erik Mylroie   +4 more
doaj   +1 more source

Identification and Quantification of a Toxigenic and Non-Toxigenic Aspergillus flavus Strain in Contaminated Maize Using Quantitative Real-Time PCR

Toxins, 2016
Aflatoxins, which are produced by Aspergillus flavus, are toxic to humans, livestock, and pets. The value of maize (Zea mays) grain is markedly reduced when contaminated with aflatoxin.
J. Erik Mylroie, Seval Ozkan, Renuka Shivaji, Gary L. Windham, Michael N. Alpe, W. Paul Williams   +5 more
doaj   +1 more source

Unlocking COVID therapeutic targets: A structure-based rationale against SARS-CoV-2, SARS-CoV and MERS-CoV Spike

Computational and Structural Biotechnology Journal, 2020
There are no approved target therapeutics against SARS-CoV-2 or other beta-CoVs. The beta-CoV Spike protein is a promising target considering the critical role in viral infection and pathogenesis and its surface exposed features. We performed a structure-
João Trigueiro-Louro, Vanessa Correia, Inês Figueiredo-Nunes, Marta Gíria, Helena Rebelo-de-Andrade   +4 more
doaj   +1 more source

Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

Molecular Systems Biology, 2020
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant, Sebastian Baumgarten, Florent Dingli, Damarys Loew, Ameya Sinha, Aurélie Claës, Peter R Preiser, Peter C Dedon, Artur Scherf   +8 more
doaj   +1 more source

Differential Expression of Signaling Pathway Genes Associated With Aflatoxin Reduction Quantitative Trait Loci in Maize (Zea mays L.)

Frontiers in Microbiology, 2019
The roles of signaling pathway genes related to the aflatoxin reduction trait in maize were studied for the improvement of maize resistance to the fungal pathogen Aspergillus flavus (A. flavus). In this study, 55 maize genes in plant–pathogen interaction
Felicia Parish, W. Paul Williams, Gary L. Windham, Xueyan Shan   +3 more
doaj   +1 more source