Results 21 to 30 of about 674,293 (317)

Identification and Quantification of a Toxigenic and Non-Toxigenic Aspergillus flavus Strain in Contaminated Maize Using Quantitative Real-Time PCR

Toxins, 2016
Aflatoxins, which are produced by Aspergillus flavus, are toxic to humans, livestock, and pets. The value of maize (Zea mays) grain is markedly reduced when contaminated with aflatoxin.
J. Erik Mylroie, Seval Ozkan, Renuka Shivaji, Gary L. Windham, Michael N. Alpe, W. Paul Williams   +5 more
doaj   +1 more source

Unlocking COVID therapeutic targets: A structure-based rationale against SARS-CoV-2, SARS-CoV and MERS-CoV Spike

Computational and Structural Biotechnology Journal, 2020
There are no approved target therapeutics against SARS-CoV-2 or other beta-CoVs. The beta-CoV Spike protein is a promising target considering the critical role in viral infection and pathogenesis and its surface exposed features. We performed a structure-
João Trigueiro-Louro, Vanessa Correia, Inês Figueiredo-Nunes, Marta Gíria, Helena Rebelo-de-Andrade   +4 more
doaj   +1 more source

The age and evolution of an antiviral resistance mutation in Drosophila melanogaster [PDF]

, 2007
What selective processes underlie the evolution of parasites and their hosts? Arms-race models propose that new host-resistance mutations or parasite counter-adaptations arise and sweep to fixation.
Obbard, Darren J, Haddrill, Penelope R, Kim, Kang-Wook, Obbard, Darren J.; id_orcid, Haddrill, Penelope R., Bangham, Jenny, Jiggins, Francis M, Jiggins, Francis M.   +7 more
core   +1 more source

Differential Expression of Signaling Pathway Genes Associated With Aflatoxin Reduction Quantitative Trait Loci in Maize (Zea mays L.)

Frontiers in Microbiology, 2019
The roles of signaling pathway genes related to the aflatoxin reduction trait in maize were studied for the improvement of maize resistance to the fungal pathogen Aspergillus flavus (A. flavus). In this study, 55 maize genes in plant–pathogen interaction
Felicia Parish, W. Paul Williams, Gary L. Windham, Xueyan Shan   +3 more
doaj   +1 more source

Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

Molecular Systems Biology, 2020
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant, Sebastian Baumgarten, Florent Dingli, Damarys Loew, Ameya Sinha, Aurélie Claës, Peter R Preiser, Peter C Dedon, Artur Scherf   +8 more
doaj   +1 more source

Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1 [PDF]

, 2010
Fungal and oomycete plant pathogens translocate effector proteins into host cells to establish infection. However, virulence targets and modes of action of their effectors are unknown.
Hein, I., Dixelius, Christina, Hein, I, Hein, Ingo, Bryan, G, Dixelius, C., Kamoun, S., Gilroy, EM, Bos, JIB, Sadanandom, A, Boevink, PC, Gilroy, Eleanor M., Armstrong, MR, Bos, J. I. B., Taylor, RM, Bos, Jorunn I. B., Zhendong, T., Sadanandom, A., Boevink, Petra C., Dixelius, C, Engelhardt, Stefan, Bryan, Glenn, Birch, PRJ, Armstrong, M. R., Engelhardt, S, Hein, Ingo; id_orcid, Harrower, Brian, Kamoun, Sophien, Whisson, Stephen C., Vetukuri, R. R., Birch, Paul R. J.; id_orcid, Bryan, G., Vetukuri, RR, Engelhardt, S., Whisson, S. C., Tian, ZD, Whisson, SC, Boevink, P. C., Bryan, Glenn J., Bos, Jorunn, Gilroy, E. M., Sadanandom, Ari, Birch, Paul R. J., Harrower, B., Harrower, B, Vetukuri, Ramesh R., Birch, P. R. J., Taylor, R. M., Armstrong, Miles R., Taylor, Rosalind M., Zhendong, Tian, Kamoun, S, Tian, Zhendong   +52 more
core   +1 more source

Application of quantitative proteomics to discover biomarkers for tick resistance in cattle

Frontiers in Immunology, 2023
IntroductionBreeding for tick resistance is a sustainable alternative to control cattle ticks due to widespread resistance to acaricidal drugs and the lack of a protective vaccine.
Ali Raza, Benjamin L. Schulz, Amanda Nouwens, Muhammad Noman Naseem, Muhammad Kamran, Emily F. Mantilla Valdivieso, Edward D. Kerr, Constantin Constantinoiu, Nicholas N. Jonsson, Peter James, Ala E. Tabor, Ala E. Tabor   +11 more
doaj   +1 more source

The integrated concept of disease resistance; a new view including horizontal and vertical resistance in plants

, 1977
Horizontal, uniform, race-non-specific or stable resistance can be discerned according to Van der Plank, from vertical, differential, race-specific or unstable resistance by a test in which a number of host genotypes (cultivars or clones) are tested ...
Zadoks, J.C., Parlevliet, J.E.
core   +1 more source

Host Cell Signalling and Leishmania Mechanisms of Evasion

Journal of Tropical Medicine, 2012
Leishmania parasites are able to secure their survival and propagation within their host by altering signalling pathways involved in the ability of macrophages to kill pathogens or to engage adaptive immune system.
Marina Tiemi Shio, Kasra Hassani, Amandine Isnard, Benjamin Ralph, Irazu Contreras, Maria Adelaida Gomez, Issa Abu-Dayyeh, Martin Olivier   +7 more
doaj   +1 more source

Evaluation of African-Bred Maize Germplasm Lines for Resistance to Aflatoxin Accumulation

Agronomy, 2016
Aflatoxins, produced by the fungus Aspergillus flavus, contaminate maize grain and threaten human food and feed safety. Plant resistance is considered the best strategy for reducing aflatoxin accumulation. Six maize germplasm lines, TZAR101–TZAR106, were
Robert L. Brown, W. Paul Williams, Gary L. Windham, Abebe Menkir, Zhi-Yuan Chen   +4 more
doaj   +1 more source