Results 161 to 170 of about 2,727,731 (214)

Changes throughout a Genetic Network Mask the Contribution of Hox Gene Evolution. [PDF]

Curr Biol, 2019
Liu Y, Ramos-Womack M, Han C, Reilly P, Brackett KL, Rogers W, Williams TM, Andolfatto P, Stern DL, Rebeiz M.   +9 more
europepmc   +1 more source

Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors.

Development
Cooper F, Souilhol C, Haston S, Gray S, Boswell K, Gogolou A, Frith TJR, Stavish D, James BM, Bose D, Kim Dale J, Tsakiridis A.   +11 more
europepmc   +1 more source

Ancient Origin of the Hox Gene Cluster

Nature Reviews Genetics, 2001
The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra,
Peter Holland, David Ferrier, P W Holland   +2 more
exaly   +2 more sources

Human HOX Gene Disorders

Molecular Genetics and Metabolism, 2014
The Hox genes are an evolutionarily conserved family of genes, which encode a class of important transcription factors that function in numerous developmental processes. Following their initial discovery, a substantial amount of information has been gained regarding the roles Hox genes play in various physiologic and pathologic processes.
Shane C. Quinonez, Jeffrey W Innis
exaly   +3 more sources

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Hox genes and study of Hox genes in crustacean

Chinese Journal of Oceanology and Limnology, 2004
Homeobox genes have been discovered in many species. These genes are known to play a major role in specifying regional identity along the anterior-posterior axis of animals from a wide range of phyla. The products of the homeotic genes are a set of evolutionarily conserved transcription factors that control elaborate developmental processes and specify
Hou Lin, Chen Zhijuan, Xu Mingyu, Lin Shengguo, Wang Lu   +4 more
openaire   +1 more source

The puzzle of Hox genes

The International Journal of Developmental Biology, 1994
During the last few years, the regionalization of the rostral-caudal axis has been extensively studied through treatments with RA and genetic manipulations of Hox-C genes. RA shifts several Hox expression boundaries rostrally, deletes anterior rhombomeres but expands the caudal ones, and induces homeotic transformations in the vertebral column.
A E, Carrasco, S L, López
openaire   +2 more sources

Endocrine Regulation of HOX Genes [PDF]

Endocrine Reviews, 2006
Hox genes have a well-characterized role in embryonic development, where they determine identity along the anteroposterior body axis. Hox genes are expressed not only during embryogenesis but also in the adult, where they are necessary for functional differentiation.
Hugh S. Taylor, Gaurang S Daftary
exaly   +3 more sources

The Hox Genes and Their Roles in Oncogenesis

Nature Reviews Cancer, 2010
Hox genes, a highly conserved subgroup of the homeobox superfamily, have crucial roles in development, regulating numerous processes including apoptosis, receptor signalling, differentiation, motility and angiogenesis. Aberrations in Hox gene expression have been reported in abnormal development and malignancy, indicating that altered expression of Hox
Saraswati Sukumar, Nilay Shah
exaly   +3 more sources

Hox Gene Duplication in Fish

Seminars in Cell and Developmental Biology, 1999
The study of Hox gene clusters continues to serve as a paradigm for those interested in vertebrate genome evolution. Recent exciting discoveries about Hox gene composition in fishes challenges conventional views about vertebrate Hox gene evolution, and has initiated lively debates concerning the evolutionary events making the divergence of the major ...
Edmund J Stellwag
exaly   +3 more sources