Results 181 to 190 of about 2,727,731 (214)
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Hox genes and kidney patterning
Current Opinion in Nephrology and Hypertension, 2003Hox gene activity is essential for proper organization or pattern of the vertebrate body plan and is necessary for organogenesis. Sequence conservation within this family of genes is high yet they are involved in very diverse developmental processes.
Larry T, Patterson, S Steven, Potter
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Hox genes regulation in vertebrates
Developmental Dynamics, 2013Hox genes encode transcription factors defining cellular identities along the major and secondary body axes. Their coordinated expression in both space and time is critical for embryonic patterning. Accordingly, Hox genes transcription is tightly controlled at multiple levels, and involves an intricate combination of local and long‐range cis‐regulatory
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Hox genes, clusters and collinearity
The International Journal of Developmental Biology, 2018This year marks the 40th anniversary of the discovery by Ed Lewis of the property of collinearity in the bithorax gene complex in Drosophila. This landmark work illustrated the need to understand regulatory mechanisms that coordinate expression of homeotic gene clusters.
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Invasion & metastasis, 1995
Knowledge about transcription factors is crucial for understanding the molecular basis of neoplasia. Homeobox-containing genes are a family of transcription factors mostly involved in normal development. Class I human homeobox-containing genes (HOX genes) are organized in four clusters on different chromosomes.
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Knowledge about transcription factors is crucial for understanding the molecular basis of neoplasia. Homeobox-containing genes are a family of transcription factors mostly involved in normal development. Class I human homeobox-containing genes (HOX genes) are organized in four clusters on different chromosomes.
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Modulating Hox Gene Functions During Animal Body Patterning
Nature Reviews Genetics, 2005William McGinnis, Joseph C Pearson
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