Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV [PDF]
Heartland bandavirus (HRTV) is an emerging tick-borne virus that is distributed in the United States and that causes febrile illness with thrombocytopenia and leukocytopenia.
Hikaru Fujii+18 more
doaj +7 more sources
Characterization of an archaeal virus-host system reveals massive genomic rearrangements in a laboratory strain [PDF]
Halophilic archaea (haloarchaea) are known to exhibit multiple chromosomes, with one main chromosome and one or several smaller secondary chromosomes or megaplasmids.
Coraline Mercier+5 more
doaj +6 more sources
Glucosylceramide is essential for Heartland and Dabie bandavirus glycoprotein-induced membrane fusion [PDF]
Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV).
Tian Xia+10 more
doaj +4 more sources
The Lone Star tick, Amblyomma americanum, salivary factors exacerbate the clinical outcome of Heartland virus disease in a small animal model [PDF]
Heartland virus was first isolated in 2009 from two patients in Missouri and is transmitted by the Lone Star tick, Amblyomma americanum. To understand disease transmission and pathogenesis, it is necessary to develop an animal model which utilizes the ...
Erin S. Reynolds+3 more
doaj +3 more sources
Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States [PDF]
Heartland virus (HRTV) disease is an emerging tickborne illness in the midwestern and southern United States. We describe a reported fatal case of HRTV infection in the Maryland and Virginia region, states not widely recognized to have human HRTV ...
Sichen Liu+14 more
doaj +3 more sources
Heartland Virus Disease—An Underreported Emerging Infection [PDF]
First recognized 15 years ago, Heartland virus disease (Heartland) is a tickborne infection contracted from the transmission of Heartland virus (HRTV) through tick bites from the lone star tick (Amblyomma americanum) and potentially other tick species ...
Zygmunt F. Dembek+3 more
doaj +3 more sources
Pathogenesis and virulence of Heartland virus [PDF]
Heartland virus (HRTV), an emerging tick-borne pathogenic bunyavirus, has been a concern since 2012, with an increasing incidence, expanding geographical distribution, and high pathogenicity in the United States.
Kuan Feng+6 more
doaj +3 more sources
Geographical distribution and pathogenesis of ticks and tick-borne viral diseases [PDF]
Ticks are obligatory hematophagous arthropods that harbor and transmit infectious pathogens to humans and animals. Tick species belonging to Amblyomma, Ixodes, Dermacentor, and Hyalomma genera may transmit certain viruses such as Bourbon virus (BRBV ...
Taif Shah+9 more
doaj +3 more sources
A bibliometric and visualized analysis of heartland virus [PDF]
BackgroundHeartland virus (HRTV) is an emerging tick-borne bunyavirus first detected in 2009. The purpose of this study was to utilize bibliometric analysis to assess the research trends, key foci, and progress of HRTV.
Huiying Zhang+3 more
doaj +3 more sources
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019 [PDF]
Report of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018–2019 in 26 sites near where seropositive deer were captured and the residence of the human case ...
Yamila Romer+8 more
doaj +3 more sources