Results 21 to 30 of about 909 (130)
Secondary hemophagocytic lymphohistiocytosis due to Heartland virus [PDF]
Carolyn G Ahlers +2 more
exaly +2 more sources
Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA. [PDF]
Heartland and Bourbon viruses are pathogenic tick-borne viruses putatively transmitted by Amblyomma americanum, an abundant tick species in Missouri. To assess the prevalence of these viruses in ticks, we collected 2778 ticks from eight sampling sites at
Aziati ID +9 more
europepmc +3 more sources
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Report of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018–2019 in 26 sites near where seropositive deer were captured and the residence of the human case ...
Yamila Romer +8 more
doaj +1 more source
Humoral immunity to phlebovirus infection
Phleboviruses are global zoonotic pathogens that can cause severe disease when transmitted to humans. Here we discuss how studying antibody responses during natural infection and the identification of neutralizing epitopes on the mature polyproteins Gn and Gc are informing the development of phlebovirus vaccines.
Katie J. Doores
wiley +1 more source
ISG20: an enigmatic antiviral RNase targeting multiple viruses
ISG20 is a broad antiviral inhibitor and a potent RNase in vitro. However, a precise understanding of its mechanism of action is lacking. In this review, we discuss the latest developments on this fascinating innate defense factor. Interferon‐stimulated gene 20 kDa protein (ISG20) is a relatively understudied antiviral protein capable of inhibiting a ...
Séverine Deymier +3 more
wiley +1 more source
The viral susceptibility of the Haloferax species [PDF]
Viruses can infect members of all three domains of life. However, little is known about viruses infecting archaea and the mechanisms that determine their host interactions are poorly understood.
Lequime, Sébastian +4 more
core +5 more sources
Enzymatic Assays to Explore Viral mRNA Capping Machinery
To escape recognition by the host innate immune system, viruses often incorporate 5′ caps into their mRNAs. The differences in mRNA capping make this process an interesting therapeutic target. Here, we review methods to explore the enzymes involved in cap biosynthesis. Such methods allow inhibitor selection, facilitating antiviral drug discovery, which
Renata Kasprzyk, Jacek Jemielity
wiley +1 more source
Abstract Bottom center drain circular tanks in which water is injected tangentially to the tank wall are widely used in aquaculture. However, a torus‐shaped region about the center drain can develop into an irrotational zone that generates low velocities and poor mixing.
Myong‐Guk Sin +4 more
wiley +1 more source
Summary Microbial communities in hypersaline underground waters derive from ancient organisms trapped within the evaporitic salt crystals and are part of the poorly known subterranean biosphere. Here, we characterized the viral and prokaryotic assemblages present in the hypersaline springs that dissolve Triassic‐Keuper evaporite rocks and feed the ...
Mª Dolores Ramos‐Barbero +9 more
wiley +1 more source
Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease
Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj +1 more source

