Results 21 to 30 of about 414 (97)
Enzymatic Assays to Explore Viral mRNA Capping Machinery
ChemBioChem, Volume 22, Issue 23, Page 3236-3253, December 2, 2021., 2021 To escape recognition by the host innate immune system, viruses often incorporate 5′ caps into their mRNAs. The differences in mRNA capping make this process an interesting therapeutic target. Here, we review methods to explore the enzymes involved in cap biosynthesis. Such methods allow inhibitor selection, facilitating antiviral drug discovery, which
Renata Kasprzyk, Jacek Jemielity
wiley +1 more source
Journal of the World Aquaculture Society, Volume 52, Issue 6, Page 1221-1233, December 2021., 2021 Abstract Bottom center drain circular tanks in which water is injected tangentially to the tank wall are widely used in aquaculture. However, a torus‐shaped region about the center drain can develop into an irrotational zone that generates low velocities and poor mixing.
Myong‐Guk Sin +4 more
wiley +1 more source
Environmental Microbiology, Volume 23, Issue 7, Page 3477-3498, July 2021., 2021 Summary Microbial communities in hypersaline underground waters derive from ancient organisms trapped within the evaporitic salt crystals and are part of the poorly known subterranean biosphere. Here, we characterized the viral and prokaryotic assemblages present in the hypersaline springs that dissolve Triassic‐Keuper evaporite rocks and feed the ...
Mª Dolores Ramos‐Barbero +9 more
wiley +1 more source
Heartland Virus in Lone Star Ticks, Alabama, USA
Emerging Infectious Diseases, 2020 We detected Heartland virus (HRTV) in lone star nymphs collected in 2018 in northern Alabama, USA. Real-time reverse transcription PCR selective for the small segment of the HRTV genome and confirmatory sequencing of positive samples showed high identity
Brent C. Newman +7 more
doaj +1 more source
Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease
Zoonotic Diseases, 2023 Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj +1 more source
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target
Cell Reports, 2020 Summary: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Wenjie Wang +11 more
doaj +1 more source
Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014
Emerging Infectious Diseases, 2015 Since its discovery in 2009, the tickborne Heartland virus (HRTV) has caused human illness in Missouri, Oklahoma, and Tennessee USA. To better assess the geographic distribution of HRTV, we used wildlife serology as an indicator.
Kasen K. Riemersma, Nicholas Komar
doaj +1 more source
The genome sequence of Lone Star virus, a highly divergent bunyavirus found in the Amblyomma americanum tick. [PDF]
PLoS ONE, 2013 Viruses in the family Bunyaviridae infect a wide range of plant, insect, and animal hosts. Tick-borne bunyaviruses in the Phlebovirus genus, including Severe Fever with Thrombocytopenia Syndrome virus (SFTSV) in China, Heartland virus (HRTV) in the ...
Andrea Swei +7 more
doaj +1 more source
Heartland Virus Transmission, Suffolk County, New York, USA
Emerging Infectious Diseases, 2021 During 2018, Heartland virus RNA was detected in an Amblyomma americanum tick removed from a resident of Suffolk County, New York, USA. The person showed seroconversion.
Alan P. Dupuis +14 more
doaj +1 more source
Heartland virus: a novel and emerging tick-borne encephalitis
Revista Mvz Cordoba, 2016 Heartland virus (HRTV) is a Bunyaviridae, phlebovirus that it has recently emerged as the causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States and China.
Salim Mattar V., Marco González T.
doaj +1 more source