Widespread Circulation of Tick-Borne Viruses in Virginia—Evidence of Exposure to Heartland, Bourbon, and Powassan Viruses in Wildlife and Livestock [PDF]
Emerging tick-borne viruses such as Powassan virus (POWV), Bourbon virus (BRBV), and Heartland virus (HRTV), whilst rare, can cause severe health problems in humans.
Ahmed Garba +3 more
doaj +3 more sources
Immune Modulation and Immune-Mediated Pathogenesis of Emerging Tickborne Banyangviruses
In the last decade, the emergence of several, novel tickborne viruses have caused significant disease in humans. Of interest are the tickborne banyangviruses: Severe fever with thrombocytopenia syndrome virus (SFTSV), Heartland virus (HRTV), and Guertu ...
Hideki Ebihara
exaly +4 more sources
Heartland Virus in Lone Star Ticks, Alabama, USA [PDF]
We detected Heartland virus (HRTV) in lone star nymphs collected in 2018 in northern Alabama, USA. Real-time reverse transcription PCR selective for the small segment of the HRTV genome and confirmatory sequencing of positive samples showed high identity
Brent C. Newman +7 more
doaj +3 more sources
Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease
Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj +2 more sources
Heartland virus: a novel and emerging tick-borne encephalitis
Heartland virus (HRTV) is a Bunyaviridae, phlebovirus that it has recently emerged as the causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States and China.
Salim Mattar V., Marco González T.
doaj +5 more sources
Vertebrate Host Susceptibility to Heartland Virus [PDF]
Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed high
Angela M. Bosco-Lauth +8 more
doaj +2 more sources
Heartland Virus Epidemiology, Vector Association, and Disease Potential
First identified in two Missouri farmers exhibiting low white-blood-cell and platelet counts in 2009, Heartland virus (HRTV) is genetically closely related to severe fever with thrombocytopenia syndrome virus (SFTSV), a tick-borne phlebovirus producing ...
Aaron C. Brault +4 more
doaj +2 more sources
Influence of N-Glycosylation on Virus–Host Interactions in Halorubrum lacusprofundi [PDF]
N-glycosylation is a post-translational modification of proteins that occurs across all three domains of life. In Archaea, N-glycosylation is crucial for cell stability and motility, but importantly also has significant implications for virus–host ...
L. Johanna Gebhard +4 more
doaj +2 more sources
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target [PDF]
Summary: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Wenjie Wang +11 more
doaj +2 more sources
Identification and characterization of three monoclonal antibodies targeting the SFTSV glycoprotein and displaying a broad spectrum recognition of SFTSV-related viruses. [PDF]
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne viral pathogen that causes severe fever with thrombocytopenia syndrome (SFTS).
Xiaoli Wu +13 more
doaj +2 more sources

