Widespread Circulation of Tick-Borne Viruses in Virginia—Evidence of Exposure to Heartland, Bourbon, and Powassan Viruses in Wildlife and Livestock [PDF]
MicroorganismsEmerging tick-borne viruses such as Powassan virus (POWV), Bourbon virus (BRBV), and Heartland virus (HRTV), whilst rare, can cause severe health problems in humans.
Ahmed Garba +3 more
doaj +2 more sources
Influence of N-Glycosylation on Virus–Host Interactions in Halorubrum lacusprofundi [PDF]
Viruses, 2023 N-glycosylation is a post-translational modification of proteins that occurs across all three domains of life. In Archaea, N-glycosylation is crucial for cell stability and motility, but importantly also has significant implications for virus–host ...
L. Johanna Gebhard +4 more
doaj +2 more sources
Immune Modulation and Immune-Mediated Pathogenesis of Emerging Tickborne Banyangviruses
Vaccines, 2019 In the last decade, the emergence of several, novel tickborne viruses have caused significant disease in humans. Of interest are the tickborne banyangviruses: Severe fever with thrombocytopenia syndrome virus (SFTSV), Heartland virus (HRTV), and Guertu ...
Hideki Ebihara, Ebihara Hideki
exaly +3 more sources
Dermatological manifestations of tick-borne viral infections found in the United States [PDF]
Virology Journal, 2022 Tick-borne diseases (TBDs) are bacterial, viral, and parasitic diseases transmitted by ticks. Viral TBDs have increased in prevalence over the last decade with many new pathogenic viruses being discovered.
Ammie Rupani +2 more
doaj +2 more sources
Current insights into human pathogenic phenuiviruses and the host immune system [PDF]
VirulencePhenuiviruses are a class of segmented negative-sense single-stranded RNA viruses, typically consisting of three RNA segments that encode four distinct proteins. The emergence of pathogenic phenuivirus strains, such as Rift Valley fever phlebovirus (RVFV)
Chuan-Min Zhou +3 more
doaj +2 more sources
Comparative Analysis of Bisexual and Parthenogenetic Populations in Haemaphysalis Longicornis [PDF]
MicroorganismsHaemaphysalis longicornis, a three-host tick with a wide host range, is widely distributed in different countries and regions. It stands out among ticks due to its unique feature of having both parthenogenetic and bisexual populations.
Chaoyue Zhao +5 more
doaj +2 more sources
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Emerging Infectious Diseases, 2022 Report of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018–2019 in 26 sites near where seropositive deer were captured and the residence of the human case ...
Yamila Romer +8 more
doaj +1 more source
Secondary hemophagocytic lymphohistiocytosis due to Heartland virus [PDF]
BMJ Case Reports, 2022 Susanna Naggie +2 more
exaly +2 more sources
Humoral immunity to phlebovirus infection
Annals of the New York Academy of Sciences, Volume 1530, Issue 1, Page 23-31, December 2023., 2023 Phleboviruses are global zoonotic pathogens that can cause severe disease when transmitted to humans. Here we discuss how studying antibody responses during natural infection and the identification of neutralizing epitopes on the mature polyproteins Gn and Gc are informing the development of phlebovirus vaccines.
Katie J. Doores
wiley +1 more source
ISG20: an enigmatic antiviral RNase targeting multiple viruses
FEBS Open Bio, Volume 12, Issue 6, Page 1096-1111, June 2022., 2022 ISG20 is a broad antiviral inhibitor and a potent RNase in vitro. However, a precise understanding of its mechanism of action is lacking. In this review, we discuss the latest developments on this fascinating innate defense factor. Interferon‐stimulated gene 20 kDa protein (ISG20) is a relatively understudied antiviral protein capable of inhibiting a ...
Séverine Deymier +3 more
wiley +1 more source