Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV [PDF]
Viruses, 2022 Heartland bandavirus (HRTV) is an emerging tick-borne virus that is distributed in the United States and that causes febrile illness with thrombocytopenia and leukocytopenia.
Hikaru Fujii +18 more
doaj +6 more sources
Characterization of an archaeal virus-host system reveals massive genomic rearrangements in a laboratory strain [PDF]
Frontiers in Microbiology, 2023 Halophilic archaea (haloarchaea) are known to exhibit multiple chromosomes, with one main chromosome and one or several smaller secondary chromosomes or megaplasmids.
Coraline Mercier +5 more
doaj +6 more sources
Glucosylceramide is essential for Heartland and Dabie bandavirus glycoprotein-induced membrane fusion [PDF]
PLoS Pathogens, 2023 Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV).
Tian Xia +10 more
doaj +3 more sources
Heartland Virus in Lone Star Ticks, Alabama, USA [PDF]
Emerging Infectious Diseases, 2020 We detected Heartland virus (HRTV) in lone star nymphs collected in 2018 in northern Alabama, USA. Real-time reverse transcription PCR selective for the small segment of the HRTV genome and confirmatory sequencing of positive samples showed high identity
Brent C. Newman +7 more
doaj +3 more sources
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target [PDF]
Cell Reports, 2020 Summary: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Wenjie Wang +11 more
doaj +3 more sources
Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States [PDF]
Emerging Infectious Diseases, 2023 Heartland virus (HRTV) disease is an emerging tickborne illness in the midwestern and southern United States. We describe a reported fatal case of HRTV infection in the Maryland and Virginia region, states not widely recognized to have human HRTV ...
Sichen Liu +14 more
doaj +2 more sources
Differential Antagonism of Human Innate Immune Responses by Tick-Borne
mSphere, 2017 In recent years, several newly discovered tick-borne viruses causing a wide spectrum of diseases in humans have been ascribed to the Phlebovirus genus of the Bunyaviridae family.
Veronica V. Rezelj +5 more
doaj +5 more sources
The Lone Star tick, Amblyomma americanum, salivary factors exacerbate the clinical outcome of Heartland virus disease in a small animal model [PDF]
Scientific Reports, 2023 Heartland virus was first isolated in 2009 from two patients in Missouri and is transmitted by the Lone Star tick, Amblyomma americanum. To understand disease transmission and pathogenesis, it is necessary to develop an animal model which utilizes the ...
Erin S. Reynolds +3 more
doaj +2 more sources
A bibliometric and visualized analysis of heartland virus [PDF]
Frontiers in MicrobiologyBackgroundHeartland virus (HRTV) is an emerging tick-borne bunyavirus first detected in 2009. The purpose of this study was to utilize bibliometric analysis to assess the research trends, key foci, and progress of HRTV.
Huiying Zhang +3 more
doaj +2 more sources
Pathogenesis and virulence of Heartland virus [PDF]
VirulenceHeartland virus (HRTV), an emerging tick-borne pathogenic bunyavirus, has been a concern since 2012, with an increasing incidence, expanding geographical distribution, and high pathogenicity in the United States.
Kuan Feng +6 more
doaj +2 more sources