Widespread Circulation of Tick-Borne Viruses in Virginia—Evidence of Exposure to Heartland, Bourbon, and Powassan Viruses in Wildlife and Livestock [PDF]
MicroorganismsEmerging tick-borne viruses such as Powassan virus (POWV), Bourbon virus (BRBV), and Heartland virus (HRTV), whilst rare, can cause severe health problems in humans.
Ahmed Garba +3 more
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Influence of N-Glycosylation on Virus–Host Interactions in Halorubrum lacusprofundi [PDF]
Viruses, 2023 N-glycosylation is a post-translational modification of proteins that occurs across all three domains of life. In Archaea, N-glycosylation is crucial for cell stability and motility, but importantly also has significant implications for virus–host ...
L. Johanna Gebhard +4 more
doaj +3 more sources
Differential Antagonism of Human Innate Immune Responses by Tick-Borne
mSphere, 2017 In recent years, several newly discovered tick-borne viruses causing a wide spectrum of diseases in humans have been ascribed to the Phlebovirus genus of the Bunyaviridae family.
Veronica V. Rezelj +5 more
doaj +6 more sources
Current insights into human pathogenic phenuiviruses and the host immune system [PDF]
VirulencePhenuiviruses are a class of segmented negative-sense single-stranded RNA viruses, typically consisting of three RNA segments that encode four distinct proteins. The emergence of pathogenic phenuivirus strains, such as Rift Valley fever phlebovirus (RVFV)
Chuan-Min Zhou +3 more
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Generation of Multiple Arbovirus-like Particles Using a Rapid Recombinant Vaccinia Virus Expression Platform [PDF]
Pathogens, 2022 As demonstrated by the 2015 Zika virus outbreak in the Americas, emerging and re-emerging arboviruses are public health threats that warrant research investment for the development of effective prophylactics and therapeutics.
Yuxiang Wang +3 more
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Heartland Virus in Lone Star Ticks, Alabama, USA [PDF]
Emerging Infectious Diseases, 2020 We detected Heartland virus (HRTV) in lone star nymphs collected in 2018 in northern Alabama, USA. Real-time reverse transcription PCR selective for the small segment of the HRTV genome and confirmatory sequencing of positive samples showed high identity
Brent C. Newman +7 more
doaj +3 more sources
The Neutralizing Monoclonal Antibodies against SFTS Group Bandaviruses Suggest New Targets of Specific or Broad-Spectrum Antivirals. [PDF]
Am J Trop Med Hyg, 2023 Severe fever with thrombocytopenia syndrome virus (SFTSV), Heartland virus (HRTV) and Guertu virus (GTV) belong to the severe fever with thrombocytopenia syndrome/Heartland group of genus Bandavirus in the family Phenuiviridae of order Bunyavirales ...
Fu L +8 more
europepmc +2 more sources
Modeling Heartland virus disease in mice and therapeutic intervention with 4'-fluorouridine. [PDF]
J VirolHeartland virus (HRTV) is an emerging tick-borne bandavirus that causes a febrile illness of varying severity in humans, with cases reported in eastern and midwestern regions of the United States.
Westover JB +17 more
europepmc +2 more sources
Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease
Zoonotic Diseases, 2023 Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj +2 more sources
Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA. [PDF]
Ticks Tick Borne Dis, 2023 Heartland and Bourbon viruses are pathogenic tick-borne viruses putatively transmitted by Amblyomma americanum, an abundant tick species in Missouri. To assess the prevalence of these viruses in ticks, we collected 2778 ticks from eight sampling sites at
Aziati ID +9 more
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