Vertebrate Host Susceptibility to Heartland Virus [PDF]
Emerging Infectious Diseases, 2016 Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed high
Angela M. Bosco-Lauth +8 more
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The Viral Susceptibility of the Haloferax Species. [PDF]
Viruses, 2022 Viruses can infect members of all three domains of life. However, little is known about viruses infecting archaea and the mechanisms that determine their host interactions are poorly understood.
Aguirre Sourrouille Z +4 more
europepmc +7 more sources
Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus [PDF]
Virus ResearchHeartland virus (HRTV) causes generalized symptoms, severe shock, and multiple organ failure. We previously reported that interferon-α/β receptor knockout (IFNAR-/-) mice infected intraperitoneally with 1 × 107 tissue culture-infective dose (TCID50) of ...
Hikaru Fujii +18 more
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Heartland Virus Epidemiology, Vector Association, and Disease Potential
Viruses, 2018 First identified in two Missouri farmers exhibiting low white-blood-cell and platelet counts in 2009, Heartland virus (HRTV) is genetically closely related to severe fever with thrombocytopenia syndrome virus (SFTSV), a tick-borne phlebovirus producing ...
Aaron C. Brault +4 more
doaj +2 more sources
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target [PDF]
Cell Reports, 2020 Summary: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Wenjie Wang +11 more
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Reverse Genetics System for Heartland Bandavirus: NSs Protein Contributes to Heartland Bandavirus Virulence. [PDF]
J Virol, 2022 Heartland bandavirus (HRTV) is a tick-borne virus identified in the United States in 2009. HRTV causes fever, fatigue, decreased appetite, headache, nausea, diarrhea, and muscle or joint pain in humans.
Taniguchi S +14 more
europepmc +2 more sources
Secondary hemophagocytic lymphohistiocytosis due to Heartland virus. [PDF]
BMJ Case Rep, 2022 An older man from the mid-Southeastern USA presented with acute onset of fever, fatigue, and non-bloody diarrhoea. There was high suspicion for tick-borne illness given exposure history, clinical presentation and laboratory abnormalities.
Ahlers CG +3 more
europepmc +2 more sources
Comparison between available early antiviral treatments in outpatients with SARS-CoV-2 infection: a real-life study. [PDF]
BMC Infect Dis, 2023 Purpose: To investigate the clinical impact of three available antivirals for early COVID-19 treatment in a large real-life cohort. Methods: Between January and October 2022 all outpatients tested positive for SARS-CoV-2 referring to IRCCS S.
Rinaldi M +16 more
europepmc +3 more sources
Dermatological manifestations of tick-borne viral infections found in the United States [PDF]
Virology Journal, 2022 Tick-borne diseases (TBDs) are bacterial, viral, and parasitic diseases transmitted by ticks. Viral TBDs have increased in prevalence over the last decade with many new pathogenic viruses being discovered.
Ammie Rupani +2 more
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Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014
Emerging Infectious Diseases, 2015 Since its discovery in 2009, the tickborne Heartland virus (HRTV) has caused human illness in Missouri, Oklahoma, and Tennessee USA. To better assess the geographic distribution of HRTV, we used wildlife serology as an indicator.
Kasen K. Riemersma, Nicholas Komar
doaj +2 more sources