Results 31 to 40 of about 874 (115)

Comparative Analysis of Bisexual and Parthenogenetic Populations in Haemaphysalis Longicornis [PDF]

open access: yesMicroorganisms
Haemaphysalis longicornis, a three-host tick with a wide host range, is widely distributed in different countries and regions. It stands out among ticks due to its unique feature of having both parthenogenetic and bisexual populations.
Chaoyue Zhao   +5 more
doaj   +2 more sources

Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019

open access: yesEmerging Infectious Diseases, 2022
Report of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018–2019 in 26 sites near where seropositive deer were captured and the residence of the human case ...
Yamila Romer   +8 more
doaj   +1 more source

Humoral immunity to phlebovirus infection

open access: yesAnnals of the New York Academy of Sciences, Volume 1530, Issue 1, Page 23-31, December 2023., 2023
Phleboviruses are global zoonotic pathogens that can cause severe disease when transmitted to humans. Here we discuss how studying antibody responses during natural infection and the identification of neutralizing epitopes on the mature polyproteins Gn and Gc are informing the development of phlebovirus vaccines.
Katie J. Doores
wiley   +1 more source

ISG20: an enigmatic antiviral RNase targeting multiple viruses

open access: yesFEBS Open Bio, Volume 12, Issue 6, Page 1096-1111, June 2022., 2022
ISG20 is a broad antiviral inhibitor and a potent RNase in vitro. However, a precise understanding of its mechanism of action is lacking. In this review, we discuss the latest developments on this fascinating innate defense factor. Interferon‐stimulated gene 20 kDa protein (ISG20) is a relatively understudied antiviral protein capable of inhibiting a ...
Séverine Deymier   +3 more
wiley   +1 more source

Enzymatic Assays to Explore Viral mRNA Capping Machinery

open access: yesChemBioChem, Volume 22, Issue 23, Page 3236-3253, December 2, 2021., 2021
To escape recognition by the host innate immune system, viruses often incorporate 5′ caps into their mRNAs. The differences in mRNA capping make this process an interesting therapeutic target. Here, we review methods to explore the enzymes involved in cap biosynthesis. Such methods allow inhibitor selection, facilitating antiviral drug discovery, which
Renata Kasprzyk, Jacek Jemielity
wiley   +1 more source

A method for minimizing the zone of low water flow velocity in a bottom center drain circular aquaculture tank

open access: yesJournal of the World Aquaculture Society, Volume 52, Issue 6, Page 1221-1233, December 2021., 2021
Abstract Bottom center drain circular tanks in which water is injected tangentially to the tank wall are widely used in aquaculture. However, a torus‐shaped region about the center drain can develop into an irrotational zone that generates low velocities and poor mixing.
Myong‐Guk Sin   +4 more
wiley   +1 more source

The viral susceptibility of the Haloferax species [PDF]

open access: yes, 2022
Viruses can infect members of all three domains of life. However, little is known about viruses infecting archaea and the mechanisms that determine their host interactions are poorly understood.
Lequime, Sébastian   +4 more
core   +5 more sources

Ancient saltern metagenomics: tracking changes in microbes and their viruses from the underground to the surface

open access: yesEnvironmental Microbiology, Volume 23, Issue 7, Page 3477-3498, July 2021., 2021
Summary Microbial communities in hypersaline underground waters derive from ancient organisms trapped within the evaporitic salt crystals and are part of the poorly known subterranean biosphere. Here, we characterized the viral and prokaryotic assemblages present in the hypersaline springs that dissolve Triassic‐Keuper evaporite rocks and feed the ...
Mª Dolores Ramos‐Barbero   +9 more
wiley   +1 more source

Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease

open access: yesZoonotic Diseases, 2023
Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj   +1 more source

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