Results 31 to 40 of about 885 (130)

Phleboviruses and the Type I Interferon Response

Viruses, 2016
The genus Phlebovirus of the family Bunyaviridae contains a number of emerging virus species which pose a threat to both human and animal health. Most prominent members include Rift Valley fever virus (RVFV), sandfly fever Naples virus (SFNV), sandfly ...
Jennifer Deborah Wuerth, Friedemann Weber   +1 more
doaj   +2 more sources

Immune Modulation and Immune-Mediated Pathogenesis of Emerging Tickborne Banyangviruses

Vaccines, 2019
In the last decade, the emergence of several, novel tickborne viruses have caused significant disease in humans. Of interest are the tickborne banyangviruses: Severe fever with thrombocytopenia syndrome virus (SFTSV), Heartland virus (HRTV), and Guertu ...
Crystal A. Mendoza, Hideki Ebihara, Satoko Yamaoka   +2 more
doaj   +2 more sources

Novel haloarchaeal viruses from Lake Retba infecting Haloferax and Halorubrum species [PDF]

Environmental Microbiology, 2019
The diversity of archaeal viruses is severely undersampled compared with that of viruses infecting bacteria and eukaryotes, limiting our understanding on their evolution and environmental impacts.
Bamford, Dennis Henry, Forterre, Patrik, Krupovic, Mart, Lucas-Staat, Soizick, Mizuno, Carolina M., Oksanen, Hanna Maarit, Prajapati, Bina, Prangishvili, David, Sime-Ngando, Telesphore   +8 more
core   +3 more sources

First report of Lihan Tick virus (Phlebovirus, Phenuiviridae) in ticks, Colombia

Virology Journal, 2020
Background Tick-borne phenuivirus (TBPVs) comprise human and animal viruses that can cause a variety of clinical syndromes ranging from self-limiting febrile illness to fatal haemorrhagic fevers.
Yesica López, Jorge Miranda, Salim Mattar, Marco Gonzalez, Joel Rovnak   +4 more
doaj   +2 more sources

Comparative Analysis of Bisexual and Parthenogenetic Populations in Haemaphysalis Longicornis [PDF]

Microorganisms
Haemaphysalis longicornis, a three-host tick with a wide host range, is widely distributed in different countries and regions. It stands out among ticks due to its unique feature of having both parthenogenetic and bisexual populations.
Chaoyue Zhao, Guonan Cai, Xing Zhang, Xinyu Liu, Pengfei Wang, Aihua Zheng   +5 more
doaj   +2 more sources

Developing and characterizing monoclonal antibodies of Guertu bandavirus nucleoprotein for developing methods of Guertu bandavirus and severe fever with thrombocytopenia syndrome virus detection. [PDF]

Braz J Microbiol, 2023
Qian J, Fu L, Wu X, Wang Z, Wang H, Zeng Y, Cheng G, Deng F, Shen S.   +8 more
europepmc   +2 more sources

Humoral immunity to phlebovirus infection. [PDF]

Ann N Y Acad Sci, 2023
Phleboviruses are global zoonotic pathogens that can cause severe disease when transmitted to humans. Here we discuss how studying antibody responses during natural infection and the identification of neutralizing epitopes on the mature polyproteins Gn and Gc are informing the development of phlebovirus vaccines.
Doores KJ.
europepmc   +2 more sources

ISG20: an enigmatic antiviral RNase targeting multiple viruses

FEBS Open Bio, Volume 12, Issue 6, Page 1096-1111, June 2022., 2022
ISG20 is a broad antiviral inhibitor and a potent RNase in vitro. However, a precise understanding of its mechanism of action is lacking. In this review, we discuss the latest developments on this fascinating innate defense factor. Interferon‐stimulated gene 20 kDa protein (ISG20) is a relatively understudied antiviral protein capable of inhibiting a ...
Séverine Deymier, Camille Louvat, Francesca Fiorini, Andrea Cimarelli   +3 more
wiley   +1 more source

Enzymatic Assays to Explore Viral mRNA Capping Machinery

ChemBioChem, Volume 22, Issue 23, Page 3236-3253, December 2, 2021., 2021
To escape recognition by the host innate immune system, viruses often incorporate 5′ caps into their mRNAs. The differences in mRNA capping make this process an interesting therapeutic target. Here, we review methods to explore the enzymes involved in cap biosynthesis. Such methods allow inhibitor selection, facilitating antiviral drug discovery, which
Renata Kasprzyk, Jacek Jemielity
wiley   +1 more source

A method for minimizing the zone of low water flow velocity in a bottom center drain circular aquaculture tank

Journal of the World Aquaculture Society, Volume 52, Issue 6, Page 1221-1233, December 2021., 2021
Abstract Bottom center drain circular tanks in which water is injected tangentially to the tank wall are widely used in aquaculture. However, a torus‐shaped region about the center drain can develop into an irrotational zone that generates low velocities and poor mixing.
Myong‐Guk Sin, Chol‐Ho An, Sang‐Jin Cha, Myong‐Jin Kim, Hyon‐Nam Kim   +4 more
wiley   +1 more source