Results 41 to 50 of about 39,699 (235)
HSP60 inhibits DF-1 apoptosis through its mitochondrial signal peptide
Poultry ScienceHSP60 is implicated in many biological functions and plays a key role in maintaining oxidative stress and preserving mitochondrial integrity. Our previous study showed that HSP60 inhibits apoptosis. In this study, we further investigated the mechanism of
Shengliang Cao +5 more
doaj +1 more source
Chlamydophila abortus Pelvic Inflammatory Disease
Emerging Infectious Diseases, 2003 We report the first documented case of an extragestational infection with Chlamydophila abortus in humans. The pathogen was identified in a patient with severe pelvic inflammatory disease (PID) by sequence analysis of the ompA gene.
Gernot Walder +6 more
doaj +1 more source
Alterations in the mitochondrial proteome of neuroblastoma cells 2 in response to complex 1 inhibition [PDF]
, 2011 Increasing evidence points to mitochondrial dysfunction in Parkinson's disease (PD) associated with complex I dysfunction, but the exact pathways which lead to cell death have not been resolved.
Billett, EE +3 more
core +1 more source
Sari Pediatri, 2019 Latar belakang. Heat shock protein 60 (Hsp60) ditemukan pada individu dengan Diabetes Mellitus (DM) tipe-1 dan merupakan mimikri molecular Hsp65 pada mycobacterium.
Aman Bhakti Pulungan +2 more
doaj +1 more source
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer. [PDF]
PLoS ONE, 2014 Heat shock protein 60 (HSP60) is a chaperonin with essential functions for cell physiology and survival, and its expression correlates with prognosis in a number of malignancies. The aim of this study is to determine the relationship of HSP60 status with
Xiao-shan Li +3 more
doaj +1 more source
Hsp60 Regulation of Tumor Cell Apoptosis [PDF]
Journal of Biological Chemistry, 2008 Molecular chaperones may promote cell survival, but how this process is regulated, especially in cancer, is not well understood. Using high throughput proteomics screening, we identified the cell cycle regulator and apoptosis inhibitor survivin as a novel protein associated with the molecular chaperone Hsp60.
Ghosh, Jagadish C. +3 more
openaire +3 more sources
cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]
, 2008 mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA +5 more
core +1 more source
Long-Term Stress Adaptation as a Highly-Conserved Key Factor in Yeast Aging. [PDF]
Aging CellThis study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Kong Y +7 more
europepmc +2 more sources
Biogenesis of mitochondrial c-type cytochromes [PDF]
, 1990 Cytochromesc andc 1 are essential components of the mitochondrial respiratory chain. In both cytochromes the heme group is covalently linked to the polypeptide chain via thioether bridges. The location of the two cytochromes is in the intermembrane space;
Gonzales, Daniel H., Neupert, Walter
core +2 more sources
Hsp60 and Hsp10 as antitumour molecular agents [PDF]
Cancer Biology & Therapy, 2007 The molecular chaperones Hsp60 and Hsp10 are, according to recent reports, involved in cancer development and progression. We, for instance, have found that their expression varies with distinctive patterns in different malignancies: they are overexpressed in colorectal, exocervical and prostate carcinogenesis, and colorectal cancer progression, but ...
CAPPELLO, Francesco +5 more
openaire +2 more sources