Results 21 to 30 of about 26,329 (222)

Hsp60 Inhibitors and Modulators

, 2019
In this chapter, we focus on the 60 KDa Heat Shock Protein (Hsp60) and discuss some of its biological, molecular and pathological features. The structural and mechanistic aspect of the Hsp60 folding cycle will be also presented. We further illustrate how
Antonio Palumbo Piccionello, Marzullo, Paola, Buscemi, Silvestre, Paola Marzullo, Silvestre Buscemi, Andrea Pace, Pace, Andrea, Palumbo Piccionello, Antonio   +7 more
core   +3 more sources

Hsp60 in inflammation and autoimmunity

The canonical functions of the chaperone system (CS) are directed to maintaining protein homeostasis and preventing/counteracting the deleterious effects of stress.
Cappello, Francesco, Vitale, Alessandra Maria, Macario, Alberto J. L., Conway de Macario, Everly, Marino Gammazza, Antonella   +4 more
core   +2 more sources

Hsp60 chaperonopathies and chaperonotherapy: targets and agents. [PDF]

Expert Opinion on Therapeutic Targets, 2014
Introduction: Hsp60 (Cpn60) assembles into a tetradecamer that interacts with the co-chaperonin Hsp10 (Cpn10) to assist client polypeptides to fold, but it also has other roles, including participation in pathogenic mechanisms.
Antonio Palumbo Piccionello, Claudia Campanella, CAPPELLO, Francesco, MARINO GAMMAZZA, Antonella, Macario, AJ, Francesco Cappello, PALUMBO PICCIONELLO, Antonio, Everly Conway de Macario, Antonella Marino Gammazza, CAMPANELLA, Claudia, Andrea Pace, Alberto JL Macario, PACE, Andrea, Conway de Macario, E   +13 more
core   +5 more sources

Correction to “Environmental Enrofloxacin Exposure as a Modifiable Driver of Mitochondria‐Mediated Intestinal Aging and Barrier Dysfunction” [PDF]

Aging Cell
Aging Cell, Volume 25, Issue 7, July 2026.
europepmc   +2 more sources

Wide Distribution and Specific Resistance Pattern to Third-Generation Cephalosporins of Enterobacter cloacae Complex Members in Humans and in the Environment in Guadeloupe (French West Indies)

Frontiers in Microbiology, 2021
Species belonging to Enterobacter cloacae complex have been isolated in numerous environments and samples of various origins. They are also involved in opportunistic infections in plants, animals, and humans.
Matthieu Pot, Yann Reynaud, David Couvin, Célia Ducat, Séverine Ferdinand, François Gravey, Gaëlle Gruel, François Guérin, François Guérin, Edith Malpote, Sébastien Breurec, Sébastien Breurec, Sébastien Breurec, Antoine Talarmin, Stéphanie Guyomard-Rabenirina   +14 more
doaj   +1 more source

HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

Molecular Metabolism, 2021
Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60.
Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders   +10 more
doaj   +1 more source

Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C

mBio, 2022
The maintenance of viral protein homeostasis depends on the machinery of the infected host cells, giving us an insight into the interplay between host and virus.
Jianli Tang, Sahibzada Waheed Abdullah, Pinghua Li, Jin'en Wu, Chenchen Pei, Suyu Mu, Yunlu Wang, Shiqi Sun, Huichen Guo   +8 more
doaj   +1 more source

Draft genome sequence of Enterobacter chengduensis ECC445, isolated from fresh water in the West Indies

BMC Genomic Data, 2023
Objectives The Enterobacter cloacae complex is considered an important opportunistic pathogen. It comprises many members that remain difficult to delineate by phenotypic approaches.
Matthieu Pot, Célia Ducat, Yann Reynaud, David Couvin, Séverine Ferdinand, Sébastien Breurec, Antoine Talarmin, Stéphanie Guyomard-Rabenirina   +7 more
doaj   +1 more source

Heat shock protein 60 expression and localisation in different tissues and testis development of male cattle (cattle-yak and yak)

Folia Morphologica, 2021
BACKGROUND: Heat shock protein 60 (Hsp60) play important roles in protecting testicular development and production of sperms. This study was conducted to investigate Hsp60 gene expression and localisation in testicular development to ascertain its ...
S. Zou, P. Liu, S. Yu, Y. Cui, J. He, S. Y. Afedo, H. Zhang, R. Niayale, K. Zhao   +8 more
doaj   +1 more source

Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis. [PDF]

PLoS ONE, 2013
Spondyloarthritis (SpA) comprises a heterogeneous group of inflammatory diseases, with strong association to human leukocyte antigen (HLA)-B27. A triggering bacterial infection has been considered as the cause of SpA, and bacterial heat shock protein ...
Astrid Hjelholt, Thomas Carlsen, Bent Deleuran, Anne Grethe Jurik, Berit Schiøttz-Christensen, Gunna Christiansen, Svend Birkelund   +6 more
doaj   +1 more source