Results 31 to 40 of about 26,329 (222)

Клінічне дослідження ефективності гідрогелевих пов’язок із лідокаїном у зменшенні запалення епізіотомної рани, післяпологового стресу та болю

Український журнал Здоров'я жінки, 2023
Епізіотомія, подібно до інших хірургічних втручань, активує запальні процеси в організмі, залучаючи прозапальні маркери, такі як інтерлейкіни, цитокіни і простагландини.
M.B. Liashko, D.O. Govsieiev
doaj   +1 more source

HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation

Scientific Reports, 2021
Ectopic expression of HSP60 in vascular cells is known to activate auto-immune response that is critical to atherogenic initiation. However, the pathogenic relevance of the aberrant HSP60 upregulation in intracellular signaling pathways associated with ...
Kavita Shirsath, Apeksha Joshi, Aliasgar Vohra, Ranjitsinh Devkar   +3 more
doaj   +1 more source

Heat Shock Protein 60 in Cardiovascular Physiology and Diseases

Frontiers in Molecular Biosciences, 2020
Heat shock protein 60 (HSP60) is a highly conserved protein abundantly expressed in both prokaryotic and eukaryotic cells. In mammals, HSP60 has been primarily considered to reside in the mitochondria, where HSP60 and HSP10 form a complex and facilitate ...
Yaoyun Duan, Huayuan Tang, Kali Mitchell-silbaugh, Xi Fang, Zhen Han, Kunfu Ouyang   +5 more
doaj   +1 more source

Hyperglycaemia and oxidative stress upregulate HSP60 & HSP70 expression in HeLa cells [PDF]

, 2013
Heat Shock Proteins 60 & 70 (HSP60 & HSP70) are intracellular protein that has been shown to be present at elevated levels in systemic circulation in Type 2 Diabetes mellitus (T2DM) patients.
Ryan D Martinus, Hall, Luke, Luke Hall, Martinus, Ryan Dennis   +3 more
core   +1 more source

Djhsp60 Is Required for Planarian Regeneration and Homeostasis

Biomolecules, 2022
HSP60, a well-known mitochondrial chaperone, is essential for mitochondrial homeostasis. HSP60 deficiency causes dysfunction of the mitochondria and is lethal to animal survival.
Kexue Ma, Rui Li, Gege Song, Fangying Guo, Meng Wu, Qiong Lu, Xinwei Li, Guangwen Chen   +7 more
doaj   +1 more source

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space [PDF]

, 1992
Cytochrome b2 reaches the intermembrane space of mitochondria by transport into the matrix followed by export across the inner membrane. While in the matrix, the protein interacts with hsp60, which arrests its folding prior to export.
Ostermann, Joachim, Hartl, Franz-Ulrich, Rassow, Joachim, Neupert, Walter, Horwich, Arthur, Horwich, Arthur L., Koll, Hans, Guiard, Bernard   +7 more
core   +1 more source

Adipocytes from New Zealand Obese Mice Exhibit Aberrant Proinflammatory Reactivity to the Stress Signal Heat Shock Protein 60

Journal of Diabetes Research, 2014
Adipocytes release immune mediators that contribute to diabetes-associated inflammatory processes. As the stress protein heat shock protein 60 (Hsp60) induces proinflammatory adipocyte activities, we hypothesized that adipocytes of diabetes-predisposed ...
Tina Märker, Jennifer Kriebel, Ulrike Wohlrab, Volker Burkart, Christiane Habich   +4 more
doaj   +1 more source

N1-A4 recognizes HSP60.

, 2022
(A) Huh7 cell lysates were immunoprecipitated with N1-A4 or goat anti-HSP60 antibodies (α-HSP60), and the immunoprecipitates were detected with α-HSP60 in Western blot analysis. Red arrowhead indicates HSP60. (B) HSP60-Myc/His vector was overexpressed in
Hyun Min Lee (3609296), Min Kyu Kim (479520), Hong Seo Choi (12850975), Chun Jeih Ryu (12850978)   +3 more
core   +1 more source

Epitopes of microbial and human heat shock protein 60 and their recognition in myalgic encephalomyelitis. [PDF]

PLoS ONE, 2013
Myalgic encephalomyelitis (ME, also called Chronic Fatigue Syndrome), a common disease with chronic fatigability, cognitive dysfunction and myalgia of unknown etiology, often starts with an infection.
Amal Elfaitouri, Björn Herrmann, Agnes Bölin-Wiener, Yilin Wang, Carl-Gerhard Gottfries, Olof Zachrisson, Rϋdiger Pipkorn, Lars Rönnblom, Jonas Blomberg   +8 more
doaj   +1 more source

Disease-associated mutations in the HSPD1 gene encoding the large subunit of the mitochondrial HSP60/HSP10 chaperonin complex

Frontiers in Molecular Biosciences, 2016
Heat shock protein 60 (HSP60) forms together with heat shock protein 10 (HSP10) double-barrel chaperonin complexes that are essential for folding to the native state of proteins in the mitochondrial matrix space.
Peter Bross, Paula Fernandez-Guerra
doaj   +1 more source