Results 11 to 20 of about 158,688 (339)

Hsp70 in Redox Homeostasis [PDF]

Cells, 2022
Cellular redox homeostasis is precisely balanced by generation and elimination of reactive oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and DNA to damage cells but can also act as signaling molecules to modulate transcription factors and epigenetic pathways that determine cell survival and death.
Hong Zhang, Weibin Gong, Si Wu, Sarah Perrett   +3 more
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Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes [PDF]

Structure, 2016
Protein misfolding and aggregation are pathological events that place a significant amount of stress on the maintenance of protein homeostasis (proteostasis). For prevention and repair of protein misfolding and aggregation, cells are equipped with robust mechanisms that mainly rely on molecular chaperones.
Thomas Reid, Alderson, Jin Hae, Kim, John Lute, Markley   +2 more
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Rats’ umbilical-cord mesenchymal stem cells ameliorate mast cells and Hsp70 on ovalbumin-induced allergic rhinitis rats [PDF]

Medicinski Glasnik, 2022
Aim Allergic rhinitis (AR) is a heterogeneous condition that has been associated with inflammatory responses and is characterized by clinical typical symptoms of nasal itching, sneezing, watery discharge and congestion.
Lia Restimulia, Syafruddin Ilyas, Delfitri Munir, Agung Putra, Teti Madiadipoera, Farhat Farhat, Rosita Juwita Sembiring, Muhammad Ichwan, Nur Dina Amalina   +8 more
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HSP70 [PDF]

, 2021
Η πρωτεΐνη θερμικού σοκ Hsp70 (HSPA1A: heat shock πρωτεΐνη οικογένειας A (Hsp70) μέλος 1A) είναι η καλύτερα μελετημένη πρωτεΐνη στην οικογένεια A των Hsp70s. Πρόκειται για μια πρωτεΐνη επιβίωσης και πρωτεΐνη αντι-αποπτωτική, που σχετίζεται με πολλές ασθένειες στον άνθρωπο.
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CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis [PDF]

Scientific Reports, 2017
AbstractCLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this function have not yet been clearly elucidated. In this study, using various proteomic tools, we isolated a 70-kDa protein that interacts with
Jang, Jihye, Kim, Mi Ra, Kim, Taek-Keun, Lee, Woo Ran, Kim, Jong Heon, Heo, Kyun, Lee, Sukmook   +6 more
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Association of heat-shock protein 70.1 gene with physiological and physical performance of Bali cattle [PDF]

Veterinary World
Background and Aim: Global warming challenges cattle productivity and welfare since it affects heat stress and scarce feed. The heat-shock protein 70 (HSP70) gene is essential in cytoprotection against stressors, protecting cells from dysregulated gene ...
Ikhsan Suhendro, Ronny Rachman Noor, Jakaria Jakaria, Rudy Priyanto, Wasmen Manalu, Göran Andersson   +5 more
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Hsp70 in mitochondrial biogenesis [PDF]

, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff, A. Tzagoloff, A.J. Caplan, A.J. Caplan, B.D. Gambill, B.S. Glick, C.K. Suzuki, D. Ang, D. M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.P. Atencio, E. Ikeda, E. Kutejová, E.A. Craig, E.A. Craig, F.-U. Hartl, G.S.P. Groot, H.R.B. Pelham, J. Ostermann, J. Rassow, J.F. Dice, J.P. Hendrick, K. Liberek, L. Dyck van, M. Eilers, M. Kiebler, M. Schleyer, M.-J. Gething, M.Y. Cheng, N. Rowley, N. Wang, P. Borst, P. Terpstra, P.-J. Kang, R. A. Stuart, R.A. Stuart, R.A. Stuart, R.B. Deshaies, R.G. Hadikusumo, R.J. Nelson, R.P. Beckman, S. Lindquist, S. Rospert, S.T. Hwang, T. Langer, U.C. Manning-Krieg, W. Neupert, W. Neupert, W. Voos, W.J. Chirico, Z. Xia   +53 more
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Effect of Glutamine on Antioxidant Capacity and Lipid Peroxidation in the Breast Muscle of Heat-stressed Broilers via Antioxidant Genes and HSP70 Pathway

Animals, 2020
This study investigated whether Glutamine (Gln) could be used as an additive to improve antioxidant capacity in the breast muscle of heat-stressed broilers.
Hong Hu, Liang Chen, Sifa Dai, Jiaqi Li, Xi Bai   +4 more
doaj   +1 more source

Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA [PDF]

, 1994
Mitochondrial heat shock protein 70 (mt-Hsp70) has been shown to play an important role in facilitating import into, as well as folding and assembly of nuclear-encoded proteins in the mitochondrial matrix.
Craig, Elisabeth A., Herrmann, Johannes M., Neupert, Walter, Stuart, Rosemary A.   +3 more
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Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum [PDF]

, 2009
Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle.
Annette N. Chiang, Banumathy, Billy W. Day, Botha, Brian P. Mead, Chiu, Corinne Schneider, Craig, David A. Fidock, Donna M. Huryn, Ekland, Fernandez-Saiz, Fewell, Fewell, Fewell, Fidock, Frydman, Hartl, Hunt, Jeffrey L. Brodsky, Jiang, Juan-Carlos Valderramos, Maier, Matambo, Mayer, McClellan, McKerrow, Michael G. Klein, Midorikawa, Nadeau, Noedl, Pavithra, Pecoul, Peter Wipf, Raghavan Balachandran, Raj J. Chovatiya, Ramya, Rodina, Samantha L. Bell, Shonhai, Shonhai, Sidhu, Tang, Tonkin, Wellems, Werner, Wright, Xiaojiang S. Chen, Youker   +48 more
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