Coenzyme Q10 supplementation enhances HSP70 gene expression and preserves mitochondrial function in cryopreserved Peranakan Ettawa goat spermatozoa [PDF]
Veterinary WorldBackground and Aim: Cryopreservation is essential for the long-term preservation and dissemination of superior goat genetics but induces oxidative, osmotic, and thermal stress that compromises sperm quality and fertilizing potential.
Yudit Oktanella +5 more
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Changes of cellular stress response related hsp70 and abcb1 transcript and Hsp70 protein levels in Siberian freshwater amphipods upon exposure to cadmium chloride in the lethal concentration range [PDF]
PeerJ, 2020 The induction of cellular stress response systems, heat shock protein hsp70/Hsp70 and multixenobiotic transporter abcb1, by cadmium chloride (CdCl2) was explored in amphipod species with different stress adaptation strategies from the Lake Baikal area ...
Marina V. Protopopova +2 more
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Frontiers in Bioscience-Landmark, 2023 Background: The mortality rate of colorectal cancer (CRC) ranks second worldwide. Previous research had indicated that licochalcone A (LA) was a flavonoid in licorice with diverse anticancer effects.
Tianpeng Li +11 more
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The relationship between HSP70 and level of leptin and luteinizing hormones in female rats exposed to chronic and acute heat stress [PDF]
Iraqi Journal of Veterinary Sciences, 2020 The current search experiments designed to study the effect of chronic and acute heat stress on the relationship between HSP70, leptin and luteinizing hormones level in female rats.
Hiyam N. Matty, Ashwaq A. Hassan
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The Effects of Heat Shock Proteins on Delivery of HIV-1 Nef Antigen in Mammalian Cells
Vaccine Research, 2020 Introduction: Vaccine design is mainly considered as a therapeutic strategy to elicit HIV-specific immunity. DNA vaccines encoding an antigen and also an adjuvant can induce an effective adaptive immunity. Due to having numerous roles in viral infection,
Alireza Milani +3 more
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HSP70 promotes MLKL polymerization and necroptosis
Molecular & Cellular Oncology, 2020 Mixed lineage kinase domain-like protein (MLKL) is the proposed executioner of necroptosis. Our recent findings identify a novel inhibitor necroptosis-blocking compound 1 (NBC1) which specifically conjugates to two cysteines of heat shock protein 70 ...
Andrea N. Johnston, Zhigao Wang
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The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions? [PDF]
Cell Stress and Chaperones, 2009 Although heat shock (stress) proteins are typically regarded as being exclusively intracellular molecules, it is now apparent that they can be released from cells in the absence of cellular necrosis. We and others have reported the presence of Hsp60 (HSPD1) and Hsp70 (HSPA1A) in the circulation of normal individuals and our finding that increases in ...
A Graham, Pockley +2 more
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STUDIES ON BIOCHEMICAL RESPONSES OF TABLE SIZED LABEO ROHITA (HAMILTON, 1822) TO THE THERMAL EXPOSURE AT CRITICAL MAXIMUM TEMPERATURE (CTMAX) [PDF]
Exploratory Animal and Medical Research, 2019 Water temperature of aquatic bodies is gradually getting warmer and may pose threat for survival, health and production of fish in future. The critical temperature maximum (CTmax) is the tool to estimate the upper limit of thermal tolerance of fish but
Prasun Roychowdhury +2 more
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HSP70 and HSP90 in neurodegenerative diseases [PDF]
Neuroscience Letters, 2020 Molecular chaperones have a role to stabilize proteins or assist them in reaching their native fold. Heat shock proteins (HSPs) are a family of molecular chaperons that protect proteins from cellular stress during the assembly of protein complexes and also prevent the proteins from aggregation and disassembly.
Abha Gupta +2 more
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Genomics, 1993 The 70,000-D heat shock protein (HSP70) gene family includes both heat-inducible and constitutively expressed genes. We have mapped five murine HSP70 genes to specific sites on three separate chromosomes. Southern blot analysis of Chinese hamster x mouse somatic cell DNAs was used to assign the gene for the 78,000-D glucose-regulated protein (Grp78) to
C R, Hunt +4 more
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