Coenzyme Q10 supplementation enhances HSP70 gene expression and preserves mitochondrial function in cryopreserved Peranakan Ettawa goat spermatozoa [PDF]
Veterinary WorldBackground and Aim: Cryopreservation is essential for the long-term preservation and dissemination of superior goat genetics but induces oxidative, osmotic, and thermal stress that compromises sperm quality and fertilizing potential.
Yudit Oktanella +5 more
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Köpeklerde ovaryohisterektomi’nin HSP70 ve anti-HSP70 antikorları üzerine etkisi
Kafkas Universitesi Veteriner Fakultesi Dergisi, 2013 Bu çalışmada köpeklerde kan serumu Heat Shock Protein (HSP) 70 ve anti-HSP 70 antikorlarının düzeyleri üzerine ovaryohisterektominin etkilerinin belirlenmesi amaçlanmıştır. Bu amaçla, 87 adet dişi sokak köpeği materyal olarak kullanıldı.
Murat Yüksel +2 more
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CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis [PDF]
Scientific Reports, 2017 CLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this function have not yet been clearly elucidated. In
Sukmook Lee +6 more
core +6 more sources
Kaliandra honey improves testosterone levels, diameter and epithelial thickness of seminiferous tubule of white rat (Rattus norvegicus) due to malnutrition through stimulation of HSP70 [PDF]
Open Veterinary Journal, 2021 Background: Malnutrition can cause an increase in oxidative stress as it triggers the expression of Heat Shock Protein70 (HSP70), a chaperon molecule that is needed to repair damaged cells within optimal levels.
Nefranindy Rahma +5 more
doaj +1 more source
Hsp70, in Combination with IL-15 and PD-1 Blocker, Interferes with The Induction of Cytotoxic NK Cells in Relapsed Acute Myeloid Leukemia Patients [PDF]
Cell Journal, 2023 Objective: Natural killer (NK) cells are critical immune cells for acute myeloid leukemia (AML) targeting. However,little is known about the relationship between using checkpoint inhibitors and heat shock protein 70 (Hsp70) as NK cellactivators to ...
Javad Firouzi +8 more
doaj +1 more source
Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70. [PDF]
, 2022 Heat Shock Protein 70s (HSP70s) are key molecular chaperones that are overexpressed in many cancers and often associated with metastasis and poor prognosis. It has proven difficult to develop ATP-competitive, drug-like small molecule inhibitors of HSP70s
Reynisson
core +1 more source
Medicine Science, 2023 Cervical and ovarian cancer are two aggressive neoplasms for women, still with high mortality and morbidity. Among the molecules and compounds that have anticancer activity, it was studied the JG-98, a heat shock protein 70 (HSP70) inhibitor.
Nazan Yurtcu +4 more
doaj +1 more source
Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes [PDF]
Structure, 2016 Protein misfolding and aggregation are pathological events that place a significant amount of stress on the maintenance of protein homeostasis (proteostasis). For prevention and repair of protein misfolding and aggregation, cells are equipped with robust mechanisms that mainly rely on molecular chaperones.
Thomas Reid, Alderson +2 more
openaire +2 more sources
Interplay between RNA interference and heat shock response systems in Drosophila melanogaster [PDF]
Open Biology, 2016 The genome expression pattern is strongly modified during the heat shock response (HSR) to form an adaptive state. This may be partly achieved by modulating microRNA levels that control the expression of a great number of genes that are embedded within ...
S. Yu Funikov +9 more
doaj +1 more source
Applied Sciences, 2022 Silver is back in vogue today as this metal is used in the form of nanomaterials in numerous commercial products. We have developed in-gel electrophoretic techniques to measure the activity of the antioxidant enzymes catalase (CAT), superoxide dismutase (
Candida Lorusso +3 more
doaj +1 more source