Results 31 to 40 of about 111,857 (291)

The Hsp70-Hsp90 Chaperone Cascade in Protein Folding.

Trends in Cell Biology, 2019
Conserved families of molecular chaperones assist protein folding in the cell. Here we review the conceptual advances on three major folding routes: (i) spontaneous, chaperone-independent folding; (ii) folding assisted by repetitive Hsp70 cycles; and ...
Tania Morán Luengo, M. Mayer, S. Rüdiger   +2 more
semanticscholar   +1 more source

Association of nocturnal intermittent hypoxia with heat shock protein 70 in patients with obstructive sleep apnea: a pilot study

Russian Open Medical Journal, 2020
Introduction — Nocturnal intermittent hypoxia in obstructive sleep apnea (OSA) causes cellular stress and consequent change in inducible heat shock protein 70 (HSP70) level.
Irina M. Madaeva, Nadezhda A. Kurashova, Natalya V. Semenova, Lubov I. Kolesnikova, Sergei I. Kolesnikov   +4 more
doaj   +1 more source

DNA methylation patterns respond to thermal stress in the viviparous cockroach Diploptera punctata

Epigenetics, 2021
It is increasingly recognized that epigenetic mechanisms play a key role in acclimatization and adaptation to thermal stress in invertebrates. DNA methylation and its response to temperature variation has been poorly studied in insects.
Mariana Villalba de la Peña, Veysi Piskobulu, Christopher Murgatroyd, Reinmar Hager   +3 more
doaj   +1 more source

Chromosomal Localization of Five Murine HSP70 Gene Family Members: Hsp70.1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78

Genomics, 1993
The 70,000-D heat shock protein (HSP70) gene family includes both heat-inducible and constitutively expressed genes. We have mapped five murine HSP70 genes to specific sites on three separate chromosomes. Southern blot analysis of Chinese hamster x mouse somatic cell DNAs was used to assign the gene for the 78,000-D glucose-regulated protein (Grp78) to
C R, Hunt, D L, Gasser, D D, Chaplin, J C, Pierce, C A, Kozak   +4 more
openaire   +2 more sources

Hsp90 and Hsp70 chaperones: Collaborators in protein remodeling

Journal of Biological Chemistry, 2018
Heat shock proteins 90 (Hsp90) and 70 (Hsp70) are two families of highly conserved ATP-dependent molecular chaperones that fold and remodel proteins. Both are important components of the cellular machinery involved in protein homeostasis and participate ...
Olivier Genest, S. Wickner, Shannon M. Doyle   +2 more
semanticscholar   +1 more source

Hsp70 gene association with nuclear speckles is Hsp70 promoter specific [PDF]

Journal of Cell Biology, 2010
Many mammalian genes localize near nuclear speckles, nuclear bodies enriched in ribonucleic acid–processing factors. In this paper, we dissect cis-elements required for nuclear speckle association of the heat shock protein 70 (Hsp70) locus. We show that speckle association is a general property of Hsp70 bacterial artificial chromosome transgenes ...
Hu, Yan, Plutz, Matt, Belmont, Andrew S.
openaire   +2 more sources

Heat shock proteins in the assessment of the course and prognosis of heart failure with preserved ejection fraction

Российский кардиологический журнал
Aim. To analyze the relationship between the concentrations of circulating heat shock proteins (HSP): HSP27, HSP70 and cardiovascular HSP (cvHSP) with the course of heart failure with preserved ejection fraction (HFpEF) and the outcomes of acute ...
Yu. S. Timofeev, T. Yu. Vedenikin, A. R. Afaunova, R. A. Zamyatin, V. A. Metelskaya, O. N. Dzhioeva, A. A. Ivanova, E. A. Neshkova, M. S. Pokrovskaya, O. M. Drapkina   +9 more
doaj   +1 more source

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

Frontiers in Neuroscience, 2017
The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaques) and
Rachel E. Lackie, A. Maciejewski, Valeriy G Ostapchenko, J. Marques-Lopes, W. Choy, M. Duennwald, V. Prado, M. Prado   +7 more
semanticscholar   +1 more source

Examination the Expression Pattern of HSP70 Heat Shock Protein in Chicken PGCs and Developing Genital Ridge

Scientific Papers Animal Science and Biotechnologies, 2023
Chicken Primordial Germ cells (PGCs) are emerging pioneers in the field of applied embryology and stem cell technology. Now-a-days transgenic chickens are promising models to study human disease pathophysiology and drug designing.
Mahek Anand, Roland Tóth, Alayu Kidane, Alexandra Nagy, Bence Lázár, Eszter Patakiné Várkonyi, Krisztina Liptói, Elen Gócza   +7 more
doaj  

RNAi knockdown of heat shock proteins affects thermotolerance of Ephestia kuehniella (Lepidoptera: Pyralidae) [PDF]

Journal of Crop Protection
The Mediterranean flour moth, Ephestia kueheniella is one of the most severe pests in stores worldwide. Like many other stored product pests, chemical pesticides are often used to control this insect.
Ali Reza Bandani, Saeed Farahani
doaj   +1 more source