Results 71 to 80 of about 74,429 (262)

The hsp70 new functions as a regulator of reproduction both female and male in Ophraella communa

Frontiers in Molecular Biosciences, 2022
Heat shock proteins (Hsps) function as molecular chaperones that enable organisms to withstand stress and maintain normal life activities. In this study, we identified heat shock protein 70 (encoded by hsp70), which exhibits a higher expression in the ...
Yan Zhang, Weihua Ma, Chao Ma, Qinglu Zhang, Zhenya Tian, Zhenya Tian, Zhenqi Tian, Hongsong Chen, Hongsong Chen, Jianying Guo, Fanghao Wan, Zhongshi Zhou, Zhongshi Zhou   +12 more
doaj   +1 more source

Hsp70 in cancer: back to the future [PDF]

Oncogene, 2014
Mechanistic studies from cell culture and animal models have revealed critical roles for the heat shock protein Hsp70 in cancer initiation and progression. Surprisingly, many effects of Hsp70 on cancer have not been related to its chaperone activity, but rather to its role(s) in regulating cell signaling.
Sherman, Michael Y., Gabai, Vladimir L.
openaire   +2 more sources

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Primer informe de Leishmania naiffi en Zamora Chinchipe (Ecuador) utilizando el gen que codifica la proteína HSP70

Cedamaz, 2021
En Ecuador se encuentran informadas algunas de las especies de Leishmania pertenecientes al subgénero Viannia (V), causante de enfermedades como leishmaniasis cutánea, cutánea difusa no curativa y mucocutánea. El objetivo de este trabajo fue diagnosticar
Luis Alberto Morocho-Yaguana, Gina Stefany Jaramillo-Balcázar, Franklin Román-Cárdenas, Loidy Zamora-Gutiérrez   +3 more
doaj  

Regulation of survival gene hsp70 [PDF]

Cell Stress and Chaperones, 2012
Rapid expression of the survival gene, inducible heat shock protein 70 (hsp70), is critical for mounting cytoprotection against severe cellular stress, like elevated temperature. Hsp70 protein chaperones the refolding of heat-denatured peptides to minimize proteolytic degradation as a part of an eukaryotically conserved phenomenon referred to as the ...
Jordan Thomas, Silver, Earl G, Noble
openaire   +2 more sources

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Transcriptome analysis revealed the molecular mechanism by which Chrysanthemum naktongense roots respond to low-concentration lanthanum treatment

Ornamental Plant Research
Chrysanthemum naktongense (C. naktongense) is widely distributed in northern China, and has high biomass and strong resistance. Lanthanum is a nonessential heavy metal element in plants, and it affects C.
Yaohui Gao, Ruiqing Zhang, Ning Xu, Ying Song, Shiao Chen, Miao He   +5 more
doaj   +1 more source

Benzo[a]pyrene-induced changes in carboxylesterase, acetylcholinesterase and heat shock protein 70 of Lymantria dispar (Lepidoptera: Lymantriidae) from unpolluted and polluted forests [PDF]

Archives of Biological Sciences, 2019
Plant vegetation accumulates polycyclic aromatic hydrocarbons (PAHs) among which benzo[a]pyrene (B[a]P) is recognized as being very toxic, including cancerogenic. Lymantria dispar L. larvae are sensitive to changes in the environment, providing potential
Grčić Anja, Ilijin Larisa, Mrdaković Marija, Vlahović Milena, Filipović Aleksandra, Đurašević Siniša, Perić-Mataruga Vesna   +6 more
doaj   +1 more source

Identification of marker proteins in preterm and term birth: Relationship of rankl and HSP70 in the cord blood

Medicine Science, 2022
The goal of this research was to investigate at the expression profiles of heat shock protein 70 (HSP70) and receptor activator of nuclear factor-kappa B ligand (RANKL) in term and preterm infants.
Baris Uzunok, Selcuk Gurel
doaj   +1 more source