Results 81 to 90 of about 105,054 (297)

Transcriptome analysis revealed the molecular mechanism by which Chrysanthemum naktongense roots respond to low-concentration lanthanum treatment

open access: yesOrnamental Plant Research
Chrysanthemum naktongense (C. naktongense) is widely distributed in northern China, and has high biomass and strong resistance. Lanthanum is a nonessential heavy metal element in plants, and it affects C.
Yaohui Gao   +5 more
doaj   +1 more source

Primer informe de Leishmania naiffi en Zamora Chinchipe (Ecuador) utilizando el gen que codifica la proteína HSP70

open access: yesCedamaz, 2021
En Ecuador se encuentran informadas algunas de las especies de Leishmania pertenecientes al subgénero Viannia (V), causante de enfermedades como leishmaniasis cutánea, cutánea difusa no curativa y mucocutánea. El objetivo de este trabajo fue diagnosticar
Luis Alberto Morocho-Yaguana   +3 more
doaj  

Hsp70-nucleotide exchange factor (NEF) Fes1 has non-NEF roles in degradation of gluconeogenic enzymes and cell wall integrity

open access: yes, 2019
Fes1 is a conserved armadillo repeat-containing Hsp70 nucleotide exchange factor important for growth at high temperature, proteasomal protein degradation and prion propagation.
Daniel C. Masison (260932)   +1 more
core   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

open access: yesAdvanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu   +12 more
wiley   +1 more source

Benzo[a]pyrene-induced changes in carboxylesterase, acetylcholinesterase and heat shock protein 70 of Lymantria dispar (Lepidoptera: Lymantriidae) from unpolluted and polluted forests [PDF]

open access: yesArchives of Biological Sciences, 2019
Plant vegetation accumulates polycyclic aromatic hydrocarbons (PAHs) among which benzo[a]pyrene (B[a]P) is recognized as being very toxic, including cancerogenic. Lymantria dispar L. larvae are sensitive to changes in the environment, providing potential
Grčić Anja   +6 more
doaj   +1 more source

Cloning and characterisation of heat shock and wound-induced genes in pea (pisum sativum L.) [PDF]

open access: yes, 1997
Plant productivity in many regions of the world is limited primarily as a result of environmental stresses. High temperature and wounding caused by pest and pathogen infection are among the main factors accounting for unpredictable and often severe yield
Dhankher, Om Parkash
core  

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang   +5 more
wiley   +1 more source

A 12-mer Peptide of Tag7 (PGLYRP1) Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death

open access: yesCells, 2020
Investigation of interactions between a pro-inflammatory cytokine tumor necrosis factor (TNFα) and its receptor is required for the development of new treatments for autoimmune diseases associated with the adverse effects of TNFα.
Elena A. Romanova   +8 more
doaj   +1 more source

The proliferation and cytokine release of naïve splenocytes stimulated by rTs-Hsp70-activated DCs.

open access: yes, 2018
(A) The proliferation of naïve CD4+ T cells stimulated by rTs-Hsp70-activated DCs from WT and TLR2/4-/- mice determined by CFSE. The DCs from WT, TLR2-/- or TLR4-/- mice were pre-incubated with rTs-Hsp70 or other controls including PBS, BSA, LPS and ...
Yuli Cheng (116606)   +10 more
core   +1 more source

Pharmacological Targeting of the Hsp70 Chaperone [PDF]

open access: yesCurrent Topics in Medicinal Chemistry, 2009
The molecular chaperone, heat shock protein 70 (Hsp70), acts at multiple steps in a protein's life cycle, including during the processes of folding, trafficking, remodeling and degradation. To accomplish these various tasks, the activity of Hsp70 is shaped by a host of co-chaperones, which bind to the core chaperone and influence its functions. Genetic
Srikanth, Patury   +2 more
openaire   +2 more sources

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