The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
<i>Trichinella spiralis</i> HSP70 Mediates Mice Immune Responses via TLR2/MyD88/ERK Signaling Pathway. [PDF]
Feng J +7 more
europepmc +1 more source
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang +8 more
wiley +1 more source
Small bites for big problems: stepwise aggregate degradation by autophagy. [PDF]
Hipp MS, Mauthe M.
europepmc +1 more source
Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review
Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam +4 more
wiley +1 more source
Stress-induced nucleolar rejuvenation via chaperone-mediated segregation in a filamentous fungus. [PDF]
Rogers AM +3 more
europepmc +1 more source
The Role of Thermal Immunomodulation in Postoperative Wound Repair with a Focus on Hepatic Surgery. [PDF]
Pietrzyk B +4 more
europepmc +1 more source
Intestinal gene expression in heat-stressed broilers selected for high water efficiency. [PDF]
Lassiter K +10 more
europepmc +1 more source
Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats. [PDF]
Cai G +12 more
europepmc +1 more source

