Results 151 to 160 of about 58,138 (243)

A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels, Suzanne Fischer, David Creytens, Sándor Dedeyne, Felix De Vuyst, Cláudio Pinheiro, Fleur Cordier, Sarah‐Lee Bekaert, Nadine Van Roy, Kaat Durinck, Jarne Pauwels, Kris Gevaert, Pieter Mestdagh, Jo Vandesompele, Pekka Rappu, Jyrki Heino, An Hendrix, Gabrielle H. van Ramshorst, Gwen Sys, Olivier De Wever   +19 more
wiley   +1 more source

Functionalized Quantum Dot-Based Portable Sensor for Dual Detection of Stress Biomarkers in Blood Serum and Saliva. [PDF]

J Biophotonics
Kishore A, Varughese AM, Roth B, Zeilinger C.   +3 more
europepmc   +1 more source

Soil Microbiota and Rhizosphere Dynamics: Ecological Mechanisms Driving Crop Stress Adaptation in Climate‐Smart Agriculture

Food and Energy Security, Volume 15, Issue 4, July/August 2026.
ABSTRACT Climate change‐mediated abiotic stresses limit crop performance, and plant responses are increasingly recognized as emergent properties of the coupling between soil, plants, and microbiomes rather than inherent plant characteristics. This review synthesizes mechanistic evidence from 2020 to 2025 on how rhizosphere microbiota contribute to crop
Alaba Adewole Adebayo, Funso Raphael Kutu, Dennis Ndolo, Ma del Carmen Orozco‐Mosqueda, Gustavo Santoyo, Olubukola Oluranti Babalola   +5 more
wiley   +1 more source

Ligand-driven modulation of chaperone-cochaperone networks shapes proteostasis outcomes. [PDF]

Protein Sci
Magni A, Bonollo G, Trèves G, Frigerio F, Cinquini F, Pavoni S, Oliveira ASF, Mulholland AJ, Serapian SA, Colombo G.   +9 more
europepmc   +1 more source

Pyruvate Kinase M2 Mediates Apigenin‐Induced Energy Crisis and Apoptosis in Colon Cancer Cells

Food Frontiers, Volume 7, Issue 4, July 2026.
Apigenin, a dietary flavonoid with low toxicity, induces profound bioenergetic collapse in colon cancer cells by downregulating PKM2. This metabolic crisis, characterized by suppressed glycolysis and mitochondrial dysfunction, ultimately triggers robust apoptosis.
Ke Zhang, Xingtao Zhou, Xujie Wang, Mingyong Xie   +3 more
wiley   +1 more source

RPAP3: Structural evolution, chaperone networks, and disease implications of a transcriptional Co-chaperone. [PDF]

J Biol Chem
Antonio LM, Ramos CHI.
europepmc   +1 more source

Food and Medicinal Homologous Substances in Sleep Disorders Improvement: Current Advances and Future Perspectives

Food Frontiers, Volume 7, Issue 4, July 2026.
The schematic diagram illustrating the improvement mechanisms of six typical FMH substances and their main active ingredients in different sleep disorders. ABSTRACT Sleep integrates many brain and peripheral processes, profoundly influencing well‐being.
Wenjing Wen, Qili Li, Chenghao Lv, Jing Wen, Yihan Zhang, Yuhang Yi, Tao Li, Fang Wang, Yibo Luo, Si Qin   +9 more
wiley   +1 more source

Insights into the function and structure of the R2TP (RUVBL1-RUVBL2-RPAP3-PIH1D1)chaperone complex. [PDF]

Cell Stress Chaperones
Mohamed M, Wu R, Houry WA.
europepmc   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Galleria mellonella infected with Bacillus thuringiensis involves Hsp90

Open Life Sciences, 2013
Wojda Iwona, Kowalski Patryk
doaj   +1 more source