Characterization of the New Pentafluorosulfanyl-Substituted Chalcone 246TMP-3SF5 as a Potential New Treatment Option Against Hepatocellular Carcinoma. [PDF]
Viperino A +8 more
europepmc +1 more source
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo +5 more
wiley +1 more source
NN-01-195, a Novel Conjugate of HSP90 and AURKA Inhibitors, Effectively Targets Solid Tumors. [PDF]
Nguyen TT +15 more
europepmc +1 more source
Engineering Photothermal Nanoplatforms for Multimodal Theranostics and Biosensing
ABSTRACT Photothermal platforms bridge materials science and biomedicine, emerging as a transformative frontier in biomedical applications. They offer spatiotemporally precise, noninvasive modalities with cell‐type‐independent efficacy for treating a range of diseases.
Xiao Han +3 more
wiley +1 more source
Galleria mellonella infected with Bacillus thuringiensis involves Hsp90
Wojda Iwona, Kowalski Patryk
doaj +1 more source
Correction: Hsp90 interacts with Tm-22 and is essential for Tm-22-mediated resistance to <i>Tobacco mosaic virus</i>. [PDF]
Qian L +5 more
europepmc +1 more source
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
Proteostasis Dysfunction and Heat Shock Protein Networks in Intervertebral Disc Degeneration: Molecular Mechanisms and Therapeutic Opportunities. [PDF]
Wang Z +5 more
europepmc +1 more source
Identification of Sodium/Myo‐Inositol Transporter 1 as a Major Determinant of Arterial Contractility
The tonicity‐responsive enhancer binding‐protein (TonEBP) and serum glucocorticoid kinase (SGK) sense a rise in extracellular hypertonicity resulting in an increase SMIT1 membrane abundance in vascular smooth muscle cells. SMIT1 associates with Kv7.4/5, Gβγ, and KCNE4, promoting hyperpolarization, reduced voltage‐gated calcium channel (VGCC) opening ...
Elizabeth A. Forrester +6 more
wiley +1 more source

