Results 11 to 20 of about 108,942 (214)

Role of heat shock in building up proteins HSP70 , HSP90, increasing anthocyanins content in callus of strawberry Fragaria ananassa Duch. [PDF]

Mesopotamia Journal of Agriculture
This study was conducted in the genetic applications laboratories of University of Mosul, College of Education for Pure Sciences. Heat shock proteins HSPs were constructed for increase of withstand long-term physical shocks, and production of resistant ...
Waad Al-Hamdani
doaj   +1 more source

The Cell-Cycle Regulatory Protein p21CIP1/WAF1 Is Required for Cytolethal Distending Toxin (Cdt)-Induced Apoptosis. [PDF]

, 2020
The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) induces lymphocytes to undergo cell-cycle arrest and apoptosis; toxicity is dependent upon the active Cdt subunit, CdtB.
Boesze-Battaglia, Kathleen, Shenker, Bruce J, Walker, Lisa M, Weiss, Robert H, Zekavat, Ali   +4 more
core   +2 more sources

Universal primers for amplifying the complete coding sequence of cytoplasmic heat shock protein 90 (HSP90) in Lepidoptera

European Journal of Entomology, 2011
Using sequence alignment, a conserved domain in the 3' untranslated region (UTR) of the cytoplasmic heat shock protein 90 (HSP90) of Lepidoptera was found. This region is highly variable in other insect groups.
Peng Jun XU, Tong LI, Jin Hua XIAO, Robert W. MURPHY, Huang DA WEI   +4 more
doaj   +1 more source

Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus [PDF]

, 2004
The tumor suppressor protein p53 is known to be transported to the nucleus along microtubular tracks by cytoplasmic dynein. However, the connection between p53 and the dynein motor protein complex has not been established.
Galigniana, Mario Daniel, Harrell, Jennifer M., Ljungman, Mats, O´Hagen, Heather M., Pratt, William B.   +4 more
core   +1 more source

Effects of ultraviolet-C and microwave irradiation on the expression of heat shock protein genes in the maize weevil (Coleoptera: Curculionidae)

European Journal of Entomology, 2016
The maize weevil, Sitophilus zeamais (Motschulsky), is a major pest of stored grain kernels. Irradiation is an established technique for controlling insects in stored grain and is a major stress factor affecting these insects.
Jatuporn TUNGJITWITAYAKUL, Nujira TATUN, Boongeua VAJARASATHIRA, Sho SAKURAI   +3 more
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MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis

Cancer Biology & Medicine, 2022
Objective: In various cancers, migration and invasion inhibitory protein (MIIP) is expressed at low level and is involved in cancer pathogenesis. Herein, we sought to explore the function of MIIP in clear cell renal cell carcinoma (ccRCC). Methods: CCK-8,
Fengqi Yan, Qinhao Wang, Mingyuan Xia, Yi Ru, Wei Hu, Guang Yan, Xin Xiong, Mei Zhang, Jiancai Wang, Qi Li, Bo Zhang, He Wang, Wei Lin, Guojun Wu, Xia Li   +14 more
doaj   +1 more source

Tah1 helix-swap dimerization prevents mixed Hsp90 co-chaperone complexes [PDF]

, 2015
Specific co-chaperone adaptors facilitate the recruitment of client proteins to the Hsp90 system. Tah1 binds the C-terminal conserved MEEVD motif of Hsp90, thus linking an eclectic set of client proteins to the R2TP complex for their assembly and ...
Ali, Back, Battye, Boulon, Chartron, Chrisostomos Prodromou, Eckert, Emsley, Forget, Gonzales, Hořejší, Itsuki, Izumi, Jiménez, Kakihara, Krissinel, Kurokawa, Laurence H. Pearl, Liou, Liu, Mohinder Pal, Morgan, Murshudov, Nagradova, Nyarko, Pal, Pearl, Polier, Prodromou, Prodromou, Rhodri M. L. Morgan, Roe, S. Mark Roe, Samarsky, Siligardi, Takai, Te, Tobaben, Tung, Vaughan, Worrall, Zhang, Zhao   +42 more
core   +1 more source

Heat Shock Protein 90 (Hsp90) Expression and Breast Cancer

Pharmaceuticals, 2012
Hsp90 is an abundant protein in mammalian cells. It forms several discrete complexes, each containing distinct groups of co-chaperones that assist protein folding and refolding during stress, protein transport and degradation. It interacts with a variety
Christos A. Papadimitriou, Konstantinos Koutsoukos, Evangelos Bournakis, Flora Zagouri   +3 more
doaj   +1 more source

In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study

Molecules, 2020
A series of benzo[g]benzothiazolo[2,3-b]quinazoline-7,12-quinones were prepared from 2-acylnaphthohydroquinones and 2-aminobenzothiazoles and were evaluated for their in vitro antiproliferative activity.
Jaime A. Valderrama, David Ríos, Giulio G. Muccioli, Pedro Buc Calderon, Julio Benites   +4 more
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Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer

Journal of Extracellular Vesicles, 2020
Evidence has been accumulating to indicate that extracellular vesicles (EVs), including exosomes, released by cancer cells can foster tumour progression.
Kisho Ono, Chiharu Sogawa, Hotaka Kawai, Manh Tien Tran, Eman A. Taha, Yanyin Lu, May Wathone Oo, Yuka Okusha, Hirohiko Okamura, Soichiro Ibaragi, Masaharu Takigawa, Ken-Ichi Kozaki, Hitoshi Nagatsuka, Akira Sasaki, Kuniaki Okamoto, Stuart K. Calderwood, Takanori Eguchi   +16 more
doaj   +1 more source