Results 141 to 150 of about 132,845 (313)
Potential role of heat shock protein 90 (Hsp90) in HIV uncoating [PDF]
, 2011 Pheroze Joshi, Cheryl A. Stoddart
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Role of Heat-Shock Proteins in Cellular Function and in the Biology of Fungi
Biotechnology Research International, 2015 Stress (biotic or abiotic) is an unfavourable condition for an organism including fungus. To overcome stress, organism expresses heat-shock proteins (Hsps) or chaperons to perform biological function.
Shraddha Tiwari, R. Thakur, J. Shankar
semanticscholar +1 more source
Proteostasis of organelles in aging and disease
The FEBS Journal, EarlyView.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
Evolvability of Chaperonin Substrate Proteins [PDF]
, 2009 Molecular chaperones ensure that their substrate proteins reach the functional native state, and prevent their aggregation. Recently, an additional function was proposed for molecular chaperones: they serve as buffers (_capacitors_) for evolution by ...
Emanuele Raineri +3 more
core +1 more source
Rethinking the role of HIF in hepatocellular carcinoma
The FEBS Journal, EarlyView.Tumor hypoxia is a hallmark of cancer driving disease, in part through activation of hypoxia‐inducible factors (HIFs). While HIF‐1α is classically understood as a hypoxia‐responsive transcription factor, its role under normoxic conditions in cells is less clear.
Niall S. Kenneth +2 more
wiley +1 more source
Hsp90 Interacts With Tm-22 and Is Essential for Tm-22-Mediated Resistance to Tobacco mosaic virus
Frontiers in Plant Science, 2018 The tomato resistance gene Tm-22 encodes a coiled coil-nucleotide binding site-leucine rich repeat type resistance protein and confers effective immune response against tobamoviruses by detecting the presence of viral movement proteins (MPs).
Lichao Qian +6 more
doaj +1 more source
Histopathology, EarlyView.PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert +5 more
wiley +1 more source
Simulation Study of the Stability of Heat Shock Protein 90 (HSP90) and Co-chaperone p23 Complex
, 2021 Lisa Matsukura, Naoyuki Miyashita
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