Results 161 to 170 of about 132,845 (313)

Discovery of novel heat shock protein (Hsp90) inhibitors based on luminespib with potent antitumor activity

open access: green, 2020
Juyoung Jung   +12 more
openalex   +1 more source

A novel function for the 90 kDa heat-shock protein (Hsp90): facilitating nuclear export of 60 S ribosomal subunits [PDF]

open access: bronze, 2002
Harald Schlatter   +4 more
openalex   +1 more source

Polymorphisms of Bovine HSP90 and Their Implications in Beef Cattle Productivity [PDF]

open access: yes, 2018
Production of beef cattle represents a $60 billion industry in the United States (USDA, 2015). The American beef cattle industry loses an estimated $370 million annually due to heat stress (St-Pierre, 2003).
Smith, Glynn G
core   +2 more sources

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė   +10 more
wiley   +1 more source

Limonoids from Guarea guidonia and Cedrela odorata: Heat Shock Protein 90 (Hsp90) Modulator Properties of Chisomicine D [PDF]

open access: hybrid, 2021
Maria Laura Bellone   +7 more
openalex   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

open access: yesExperimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths   +3 more
wiley   +1 more source

HSP90 interacts with VP37 to facilitate the cell-to-cell movement of broad bean wilt virus 2

open access: yesmBio
The systemic spread of viruses in plants requires successful viral cell-to-cell movement through plasmodesmata (PD). Viral movement proteins (MPs) interact with cellular proteins to modify and utilize host transport routes. Broad bean wilt virus 2 (BBWV2)
Myung-Hwi Kim   +7 more
doaj   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins   +4 more
wiley   +1 more source

Proteostasis collapse is a driver of cell aging and death. [PDF]

open access: yes, 2019
What molecular processes drive cell aging and death? Here, we model how proteostasis-i.e., the folding, chaperoning, and maintenance of protein function-collapses with age from slowed translation and cumulative oxidative damage.
de Graff, Adam MR   +2 more
core  

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