Results 61 to 70 of about 3,381,955 (240)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Molecular mechanisms of heat shock proteins in distinct diseases [PDF]

, 2023
Heat shock proteins (HSPs) modulate the molecular mechanics of cells and cellular systems. Properly folded proteins are required for cellular processes and organisms use molecular mechanics to keep substrate proteins in their native state.
Abay, Cansu, Tutar, Merve, Niyazov, Laziz, Yürekli, Nazlıcan, Okat, Zehra, Tutar, Yusuf, Gök Yurttaş, Asiye, Açıkalın Coşkun, Kübra, Uçar Çifçi, Kezban, Al, Mervenur, Sağır, Fatma   +10 more
core  

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Role of heat shock proteins in atrial fibrillation: From molecular mechanisms to diagnostic and therapeutic opportunities [PDF]

, 2022
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB).
Shao, Q., Han, X., Liu, D., Tse, G., Liu, T., Zhang, Z.   +5 more
core   +1 more source

The heat shock protein 90 of Toxoplasma gondii is essential for invasion of host cells and tachyzoite growth

Parasite, 2017
Toxoplasma gondii is an obligate intracellular apicomplexan parasite that infects almost all warm-blooded vertebrates. Heat shock proteins (HSP) regulate key signal transduction events in many organisms, and heat shock protein 90 (Hsp90) plays an ...
Sun Hongchao, Zhuo Xunhui, Zhao Xianfeng, Yang Yi, Chen Xueqiu, Yao Chaoqun, Du Aifang   +6 more
doaj   +1 more source

Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages

Journal of Inflammation, 2005
Background Viruses remain one of the inducers of the stress response in the infected cells. Heat shock response induced by vaccinia virus (VV) infection was studied in vitro in human blood monocyte derived macrophages (MDMs) as blood cells usually ...
Dziedzic Jakub, Slezak Kinga, Guzik Krzysztof, Kowalczyk Aleksandra, Rokita Hanna   +4 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Proteomic analysis of the heat shock and acclimation responses of Cyanobacteria [PDF]

, 2005
The cyanobacterium Synechocystis sp. PCC 6803 is a model experimental organism for proteomic research because its entire genomic sequence is available and cyanobacteria have high adaptive potential towards a variety of environmental stresses.
Hall, John James
core  

Differential roles of HSP70 and HSP90 in Senecavirus A infection: IRES-dependent translational regulation and viral replication mechanisms

Virulence
As opportunistic intracellular pathogens, viruses rely on numerous sequential interactions between host and viral factors for their replication. Given the significance of molecular chaperones (heat shock protein 70 and heat shock protein 90) in mediating
Chen Li, Yingru Ma, Chang Liu, Shaojian Xu, Jianli Shi, Jun Li   +5 more
doaj   +1 more source

In silico genomic and proteomic analyses of three heat shock proteins (HSP70, HSP90-α, and HSP90-β) in even-toed ungulates

Electronic Journal of Biotechnology, 2021
Background: Heat shock proteins (HSPs) play important roles in the responses to different environmental stresses. In this study, the genomic and proteomic characteristics of three HSPs (HSP70, HSP90-α and HSP90-β) in five even-toed ungulates (sheep ...
Sayed Haidar Abbas Raza, Abdallah A. Hassanin, Aya I.M. Dhshan, Sameh A. Abdelnour, Rajwali Khan, Chugang Mei, Linsen Zan   +6 more
doaj   +1 more source