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Anti-HSV-1 agents: an update. [PDF]
Front PharmacolHerpes simplex virus type I (HSV-1) is a member of the α-herpesvirus subfamily and is capable of causing herpes simplex keratitis, herpes labialis, and herpes simplex encephalitis. HSV-1 is well known for its lytic infections at the primary sites and for establishing latency in the sensory neuronal ganglia, with occasional recurrent infections. To date,
Lv W +5 more
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Identifying the Multifactorial Triggers of Monthly Recurrent HSV-1 Reactivation: A Case Report. [PDF]
Int Med Case Rep JFetriani U, Nur'aeny N.
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Viruses, 2023 (1) Background: Epigallocatechin gallate (EGCG) has been recognized as a flavonoid showing antiviral activity against various types of DNA and RNA viruses.
Malgorzata Krzyzowska +8 more
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Viruses, 2021 In the face of new emerging respiratory viruses, such as SARS-CoV2, vaccines and drug therapies are not immediately available to curb the spread of infection.
Ling Jin, Wendy Black, Teresa Sawyer
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BMJ Open, 2023 Objectives To assess the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in patients infected with HIV in Nigeria.Design Cross-sectional design from January to June 2019.Setting Federal Teaching Hospital, Ebonyi State, Nigeria.Participants A ...
Euslar Nnenna Onu +10 more
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Hsp90 Inhibitors Prevent HSV-1 Replication by Directly Targeting UL42-Hsp90 Complex
Frontiers in Microbiology, 2022 Herpes simplex virus type I (HSV-1) is a member of the Alphaherpesvirinae family, which could initiate labial herpes caused by the reactivation of HSV-1 primary infection, and secondary infection even causes herpes encephalitis.
Shurong Qin +29 more
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“Non-Essential” Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review
Viruses, 2020 Viruses encode for structural proteins that participate in virion formation and include capsid and envelope proteins. In addition, viruses encode for an array of non-structural accessory proteins important for replication, spread, and immune evasion in ...
Christos Dogrammatzis +2 more
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Detection of herpes simplex virus in oral tongue squamous cell carcinoma
Frontiers in Pharmacology, 2023 Introduction: Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer of the oral cavity. Contradictory results have been observed on the involvement of herpes simplex virus 1 (HSV-1) in oral squamous cell carcinomas.
Tiina Koivikko +20 more
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Intracerebral recombinant HSV-1 vector does not reactivate latent HSV-1 [PDF]
Gene Therapy, 1997 Herpes simplex virus type-1 (HSV-1) has been used for gene delivery in the nervous system for the treatment of brain tumors and other neurological diseases. In most protocols, recombinant viruses containing the gene of interest are directly injected into the brain.
Q, Wang, J, Guo, W, Jia
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Vaccines, 2020 Infections with herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are a global health burden. Besides painful oral or genital lesions in otherwise healthy subjects, both viruses can cause devastating morbidity and mortality in immune-compromised and
Christiane Silke Heilingloh +9 more
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