Results 1 to 10 of about 109,486 (229)
Human lactoferrin but not lysozyme neutralizes HSV-1 and inhibits HSV-1 replication and cell-to-cell spread [PDF]
Virology Journal, 2009 The frequent oral shedding of herpes simplex virus type 1 (HSV-1) in the absence of clinical disease suggests that symptomatic HSV-1 recurrences may be inhibited by the mucosal environment.
Välimaa Hannamari +3 more
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Viruses, 2023 (1) Background: Epigallocatechin gallate (EGCG) has been recognized as a flavonoid showing antiviral activity against various types of DNA and RNA viruses.
Malgorzata Krzyzowska +8 more
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Viruses, 2021 In the face of new emerging respiratory viruses, such as SARS-CoV2, vaccines and drug therapies are not immediately available to curb the spread of infection.
Ling Jin, Wendy Black, Teresa Sawyer
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BMJ Open, 2023 Objectives To assess the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in patients infected with HIV in Nigeria.Design Cross-sectional design from January to June 2019.Setting Federal Teaching Hospital, Ebonyi State, Nigeria.Participants A ...
Euslar Nnenna Onu +10 more
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Detection of herpes simplex virus in oral tongue squamous cell carcinoma
Frontiers in Pharmacology, 2023 Introduction: Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer of the oral cavity. Contradictory results have been observed on the involvement of herpes simplex virus 1 (HSV-1) in oral squamous cell carcinomas.
Tiina Koivikko +20 more
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Intracerebral recombinant HSV-1 vector does not reactivate latent HSV-1 [PDF]
Gene Therapy, 1997 Herpes simplex virus type-1 (HSV-1) has been used for gene delivery in the nervous system for the treatment of brain tumors and other neurological diseases. In most protocols, recombinant viruses containing the gene of interest are directly injected into the brain.
J Guo, Q Wang, William Jia
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HSV-1 Cytoplasmic Envelopment and Egress [PDF]
International Journal of Molecular Sciences, 2020 Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA replication, capsid assembly, and genome packaging take place in the infected cell nucleus, which mature nucleocapsids exit by envelopment at the inner nuclear membrane then de ...
Imran Ahmad, Duncan W. Wilson
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Hsp90 Inhibitors Prevent HSV-1 Replication by Directly Targeting UL42-Hsp90 Complex
Frontiers in Microbiology, 2022 Herpes simplex virus type I (HSV-1) is a member of the Alphaherpesvirinae family, which could initiate labial herpes caused by the reactivation of HSV-1 primary infection, and secondary infection even causes herpes encephalitis.
Shurong Qin +29 more
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“Non-Essential” Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review
Viruses, 2020 Viruses encode for structural proteins that participate in virion formation and include capsid and envelope proteins. In addition, viruses encode for an array of non-structural accessory proteins important for replication, spread, and immune evasion in ...
Christos Dogrammatzis +2 more
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Vaccines, 2020 Infections with herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are a global health burden. Besides painful oral or genital lesions in otherwise healthy subjects, both viruses can cause devastating morbidity and mortality in immune-compromised and
Christiane Silke Heilingloh +9 more
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