Results 111 to 120 of about 29,786,765 (312)

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed   +5 more
wiley   +1 more source

Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1

open access: yesDrug Design, Development and Therapy, 2022
Kai Jiang,1,2 Jing Feng,2 Xia Qi,2 Lili Ran,2 Lixin Xie2 1Department of Ophthalmology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, People’s Republic of China; 2Eye Institute of Shandong First Medical University, Eye Hospital
Jiang K, Feng J, Qi X, Ran L, Xie L
doaj  

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

open access: yesFrontiers in Microbiology, 2019
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis   +5 more
doaj   +1 more source

Aqueous Supercapacitor with Wide‐Temperature Operability and over 100,000 Cycles Enabled by Water‐in‐Salt Electrolyte

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
This study presents a symmetric supercapacitor with activated carbon electrodes and a “water‐in‐salt” electrolyte (WiSE) based on lithium perchlorate, offering over 100,000 cycles with over 90 % capacity retention. The supercapacitor operates efficiently from −20 to 80 °C, enhancing performance, stability, and all‐season operability.
Zahid Ali Zafar   +5 more
wiley   +1 more source

Amentoflavone Inhibits HSV-1 and ACV-Resistant Strain Infection by Suppressing Viral Early Infection

open access: yesViruses, 2019
Infection of Herpes simplex virus 1 (HSV-1) induces severe clinical disorders, such as herpes simplex encephalitis and keratitis. Acyclovir (ACV) is the current therapeutic drug against viral infection and ACV-resistant strains have gradually emerged ...
Feng Li   +10 more
doaj   +1 more source

Drying‐Driven Microstructural Reorganization as a Key Origin of Rate Limitation in Multi‐Walled Carbon Nanotube‐Based Thick Electrodes for Lithium‐Ion Batteries

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study shows drying‐driven microstructural reorganization as a key origin of rate limitations in multi‐walled carbon nanotubes (MWCNT)‐based thick electrodes. By decoupling transport properties, the work reveals that rapid evaporation can amplify thickness‐dependent CNT agglomeration, generating coupled electronic and ionic bottlenecks. Importantly,
So Min Gong   +8 more
wiley   +1 more source

Production of an HSV-1-based oncolytic vector expressing murine SOCS3

open access: yes, 2023
reservedIl cancro è tra le prime cause di morte a livello globale. La maggior parte delle terapie attualmente disponibili nei tumori solidi non resecabili chirurgicamente ha una ridotta efficacia e non garantisce una sopravvivenza a lungo termine dalla ...
CARNIEL, ALBERTO SAVERIO
core  

Cenobamate use in super‐refractory status epilepticus: A report of three cases

open access: yesEpileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi   +11 more
wiley   +1 more source

Protection of Mice by an Apathogenic Strain of HSV-1 Against Lethal Infection by a Pathogenic Strain of HSV-1

open access: yesJournal of General Virology, 1981
DBA/2 and C57BL/6 mice were infected intraperitoneally with two different strains of herpes simplex virus type 1, HSV-1 ANG and HSV-1 WAL. Unlike HSV-1 WAL, HSV-1 ANG was apathogenic by this mode of infection. Furthermore, infection with HSV-1 ANG protected mice of both inbred strains against infections with lethal doses of pathogenic HSV-1 WAL.
C H, Schröeder, H, Engler, H, Kirchner
openaire   +2 more sources

HSV-1 spread in the whiskers area, trigeminal ganglia, brain stem and ED1+ phagocytic cells activation.

open access: yes, 2016
Transversal/coronal sections from the whiskers area (A, B, G and H) and brain stem (E–F), longitudinal/sagittal sections from the trigeminal ganglia (C, D, I and J) from HSV-1 infected BN and SHR strains at 4dpi; stained for HSV-1 marker (green) (A–J ...
Ana Garcia-Diaz (2806306)   +20 more
core   +1 more source

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