Results 101 to 110 of about 110,857 (299)

Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1

open access: yesDrug Design, Development and Therapy, 2022
Kai Jiang,1,2 Jing Feng,2 Xia Qi,2 Lili Ran,2 Lixin Xie2 1Department of Ophthalmology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, People’s Republic of China; 2Eye Institute of Shandong First Medical University, Eye Hospital
Jiang K, Feng J, Qi X, Ran L, Xie L
doaj  

HIV-associated disruption of tight and adherens junctions of oral epithelial cells facilitates HSV-1 infection and spread.

open access: yesPLoS ONE, 2014
Herpes simplex virus (HSV) types 1 and 2 are the most common opportunistic infections in HIV/AIDS. In these immunocompromised individuals, HSV-1 reactivates and replicates in oral epithelium, leading to oral disorders such as ulcers, gingivitis, and ...
Irna Sufiawati, Sharof M Tugizov
doaj   +1 more source

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

open access: yesPLoS Pathogens, 2014
Interferon-γ inducible factor 16 (IFI16) is a multifunctional nuclear protein involved in transcriptional regulation, induction of interferon-β (IFN-β), and activation of the inflammasome response. It interacts with the sugar-phosphate backbone of dsDNA and modulates viral and cellular transcription through largely undetermined mechanisms.
Karen E Johnson   +5 more
openaire   +4 more sources

Antiherpevirus activity of essential oil and inhibition of lateral diffusion in Vero cells [PDF]

open access: yes, 2007
Background: New prophylactic and therapeutic tools are needed for the treatment of herpes simplex virus infections. Several essential oils have shown to possess antiviral activity in vitro against a wide spectrum of viruses. Aim: The present study was
SADDI M   +6 more
core   +1 more source

Comparative Study of High Voltage Spinel∥Lithium Titanate Lithium‐ion Batteries in Ethylene Carbonate Free Electrolytes

open access: yesBatteries &Supercaps, Volume 8, Issue 3, March 2025.
FEC and sulfone‐based co‐solvents are investigated as EC‐free electrolytes for LNMO∥LTO cells. FEC‐containing electrolytes demonstrate enhanced electrochemical stability by stabilizing the CEI and SEI layers, mitigating transition metal migration. Conversely, sulfone electrolytes form thinner CEIs and thick, sulfur‐rich SEIs, which are less effective ...
Killian Stokes‐Rodriguez   +6 more
wiley   +1 more source

Herpes simplex virus induces the marked up-regulation of the zinc finger transcriptional factor INSM1, which modulates the expression and localization of the immediate early protein ICP0 [PDF]

open access: yes, 2011
Background Herpes simplex viruses (HSVs) rapidly shut off macromolecular synthesis in host cells. In contrast, global microarray analyses have shown that HSV infection markedly up-regulates a number of host cell genes that may play important ...
Maki Kamakura   +4 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

In vitro interaction and colocalization of HSV-1 ORF P with a cellular splicing factor (SC35) using pulldown assay [PDF]

open access: yes, 2005
Herpes simplex virus type-1 (HSV-1) causes a variety of diseases in human. This virus is a neurotropic pathogen of human that establishes latent infection in the sensory ganglia innervating the site of primary infection. A number of genes including ICP34.
Karimi, Ali., Salehi, Rasoul.
core  

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]

open access: yes, 2018
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan   +3 more
core   +2 more sources

Aqueous Supercapacitor with Wide‐Temperature Operability and over 100,000 Cycles Enabled by Water‐in‐Salt Electrolyte

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
This study presents a symmetric supercapacitor with activated carbon electrodes and a “water‐in‐salt” electrolyte (WiSE) based on lithium perchlorate, offering over 100,000 cycles with over 90 % capacity retention. The supercapacitor operates efficiently from −20 to 80 °C, enhancing performance, stability, and all‐season operability.
Zahid Ali Zafar   +5 more
wiley   +1 more source

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