Results 101 to 110 of about 21,325,054 (309)
PLoS ONE, 2014 Herpes simplex virus (HSV) types 1 and 2 are the most common opportunistic infections in HIV/AIDS. In these immunocompromised individuals, HSV-1 reactivates and replicates in oral epithelium, leading to oral disorders such as ulcers, gingivitis, and ...
Irna Sufiawati, Sharof M Tugizov
doaj +1 more source
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Biotechnology and Bioengineering, EarlyView.Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
HSV-2 shedding before and after immunisation.
, 2019 HSV-2 shedding rates were assessed over 45-day swabbing periods before immunisation, after immunisation and after booster immunisation. (A) The number of days with HSV-2 detected was normalized per year. Shown are mean values with 95% CI.
Julie L. Dutton (8138424) +11 more
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Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]
, 2007 BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre +16 more
core +1 more source
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier +7 more
wiley +1 more source
Journal of General Virology, 1981 DBA/2 and C57BL/6 mice were infected intraperitoneally with two different strains of herpes simplex virus type 1, HSV-1 ANG and HSV-1 WAL. Unlike HSV-1 WAL, HSV-1 ANG was apathogenic by this mode of infection. Furthermore, infection with HSV-1 ANG protected mice of both inbred strains against infections with lethal doses of pathogenic HSV-1 WAL.
C H, Schröeder, H, Engler, H, Kirchner
openaire +2 more sources
Production of an HSV-1-based oncolytic vector expressing murine SOCS3
, 2023 reservedIl cancro è tra le prime cause di morte a livello globale. La maggior parte delle terapie attualmente disponibili nei tumori solidi non resecabili chirurgicamente ha una ridotta efficacia e non garantisce una sopravvivenza a lungo termine dalla ...
CARNIEL, ALBERTO SAVERIO
core
An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
, 2011 Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Heather M. Coleman +13 more
core +1 more source
Initial TK-deficient HSV-1 infection in the lip alters contralateral lip challenge immune dynamics
, 2022 Primary infection with herpes simplex type 1 (HSV-1) occurring around the mouth and nose switches rapidly to lifelong latent infection in sensitive trigeminal ganglia (TG) neurons.
Legrand, Roger +8 more
core +1 more source