Results 101 to 110 of about 29,786,765 (312)
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Purification and concentration of model viruses using single‐pass tangential flow filtration
Biotechnology Progress, EarlyView.Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano +6 more
wiley +1 more source
HSV-2 parameter values and assumptions.
, 2022 HSV-2 parameter values and assumptions.
Christine Johnston (375038) +4 more
core +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Negative epidemiological association between HSV-1 and HSV-2 infections
Heliyon, 2019 Objectives: Existing evidence on an epidemiological association between herpes simplex virus (HSV) type 1 and type 2 infections remains conflicting and inconclusive.
Gheyath K. Nasrallah +2 more
doaj +1 more source
Clinical Advances in Periodontics, EarlyView.Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal +8 more
wiley +1 more source
An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
, 2011 Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Heather M. Coleman +13 more
core +1 more source
Chemistry – A European Journal, EarlyView.4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi +5 more
wiley +1 more source
PLOS Pathogens, 2018 [This corrects the article DOI: 10.1371/journal.ppat.1004503.].
Karen E Johnson +5 more
openaire +3 more sources
HSV-1 envelope proteins and their roles in entry and membrane fusion.
, 2019 (A) HSV-1 entry into cells requires the coordinated efforts of the receptor-binding glycoprotein gD (RCSB PDB: 2C36), the heterodimer gH/gL (RCSB PDB: 3M1C), and the fusogen gB (RCSB PDB: 5V2S).
Ekaterina E. Heldwein (815959) +1 more
core +1 more source