IFN-γ Primes Keratinocytes for HSV-1–Induced Inflammasome Activation [PDF]
, 2015 Gerhard E. Strittmatter +8 more
openalex +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs
Cancer Science, EarlyView.Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi +2 more
wiley +1 more source
HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes
, 2023 Elena Weiß +10 more
openalex +1 more source
Image‐Based Spatio‐Temporal Interpolation for Split Rendering
Computer Graphics Forum, EarlyView.Abstract Low‐powered devices – such as small form factor head‐mounted displays (HMDs) – struggle to deliver a smooth and high‐quality viewing experience, due to their limited power and rendering capabilities. Cloud rendering attempts to solve the quality issue, but leads to prohibitive latency and bandwidth requirements, hindering use with HMDs over ...
M. Steiner +4 more
wiley +1 more source
Herpes Simplex Virus (HSV)-2 Candidate Vaccine Virus Deleted in Glycoprotein D (ΔgD-2) Elicits High-Titer Immunoglobulin (Ig)G2 Antibodies With Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Activity, Protects Mice From Skin and Vaginal Challenge With Clinical Isolates of HSV-1 and HSV-2, and Prevents the Establishment of Latency [PDF]
, 2016 Betsy C. Herold +6 more
openalex +1 more source
Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling
Cell Proliferation, EarlyView.This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava +9 more
wiley +1 more source
Cryptococcid Sweet Syndrome in the Setting of Hydralazine‐Induced ANCA Vasculitis: A Case Report
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Acute febrile neutrophilic dermatosis, also known as Sweet syndrome, is an inflammatory skin condition characterized by the rapid onset of painful, erythematous plaques or nodules with neutrophilic infiltrate on histology. Rarely, acellular bodies surrounded by vacuolated spaces have been noted within the neutrophilic infiltrate, mimicking ...
Jenna Vroman +4 more
wiley +1 more source