Results 11 to 20 of about 78,152 (242)
Vaccines, 2020 The modified vaccinia virus Ankara (MVA), a severely attenuated strain of vaccinia virus, is a promising vector platform for viral-vectored vaccine development because of its attributes of efficient transgene expression and safety profile, among others ...
Vajini N. Atukorale +2 more
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Viruses, 2023 Adolescents and young people are particularly vulnerable to contracting STIs, including HSV-2; furthermore, vaginal shedding of HSV-2 during pregnancy can cause vertical transmission and neonatal herpes.
Julio Cesar Muñiz-Salgado +6 more
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Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine [PDF]
, 2022 ABSTRACTThe skin at the site of HSV-2 reactivation is enriched for HSV-2-specific T cells. To evaluate whether an immunotherapeutic vaccine could elicit skin-based memory T cells, we studied skin biopsies and HSV-2-reactive CD4+T cells from peripheral blood mononuclear cells (PBMCs) by T cell receptor β (TRB) sequencing before and after vaccination ...
Ford, Emily S. +18 more
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Recurrent Benign Lymphocytic Meningitis Due to HSV-2: A Case Report
Dr. Sulaiman Al Habib Medical Journal, 2023 Recurrent benign lymphocytic meningitis (RBLM) is an uncommon form of aseptic meningitis characterized by the recurrence of meningeal symptoms followed by spontaneous recovery.
Sirine Ahmad, Mohammed Alsaeed
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Human Vaccines & Immunotherapeutics, 2020 A vaccine to prevent genital herpes is an unmet public health need. We previously reported that a trivalent vaccine containing herpes simplex virus type 2 (HSV-2) glycoproteins C, D, and E (gC2, gD2, gE2) produced in baculovirus and administered with CpG/
Kevin Egan +4 more
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HSV-2: in pursuit of a vaccine [PDF]
Journal of Clinical Investigation, 2011 Herpes simplex virus type 2 (HSV-2) is one of the most prevalent sexually transmitted infections worldwide. In addition to recurrent genital ulcers, HSV-2 causes neonatal herpes, and it is associated with a 3-fold increased risk for HIV acquisition. Although many HSV-2 vaccines have been studied in animal models, few have reached clinical trials, and ...
Christine, Johnston +2 more
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Kurdistan Journal of Applied Research, 2018 Among many viral causes of miscarriage, maternal infections caused by herpes simplex virus type -1 (HSV-1) and Herpes simplex virus type-2 (HSV-2) infections are important causes.
Zainab A. Hamid +2 more
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Viruses, 2020 Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based “typing” assays.
Amanda M. Casto +6 more
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Seroprevalence of herpes simplex virus type 1 and type 2 among the migrant workers in Qatar
Virology Journal, 2023 Background Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual workers (CMWs) in Qatar who ...
Gheyath K. Nasrallah +47 more
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Disseminated HSV-2 presenting with relapsing encephalomyelitis [PDF]
Neurology Clinical Practice, 2016 A previously healthy 39-year-old woman presented with 3 weeks of progressive leg numbness. Examination showed mild bilateral iliopsoas weakness and patchy leg numbness. She was admitted, and spinal MRI revealed T2 enhancing thoracic lesions, nonenhancing cervical cord lesions (figure, A), and subtle pial and cauda equina enhancement (figure, B).
Clotilde, Hainline +6 more
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