Results 191 to 200 of about 42,636 (233)

Impact of somatic XIST deletions on ongoing XIST expression and inactive X silencing and heterochromatin. [PDF]

Hum Mol Genet
Bhangu KS, Yang C, Illing HJ, Brown CJ.
europepmc   +1 more source

Acute NIPBL depletion reveals in vivo dynamics of loop extrusion and its role in transcription activation. [PDF]

Nat Genet
Popay TM, Pant A, Munting F, Tastemel M, Black ME, Haghani N, Dixon JR.   +6 more
europepmc   +1 more source

Telomere Maintenance and Oncogenesis. [PDF]

Int J Mol Sci
Torres-Montaner A.
europepmc   +1 more source

hTERT gene amplification in hepatocellular carcinoma

hTERT gene amplification in hepatocellular carcinoma
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Cordyceptin induces apoptosis through repressing hTERT expression and inducing extranuclear export of hTERT

Journal of Bioscience and Bioengineering, 2015
Cordycepin is an adenosine analog originally extracted from Cordyceps militaris that possesses many pharmacological effects including immune activation and antioxidant and antitumor effects. However, the underlying relationship between apoptosis and telomerase activity in response to cordycepin exposure has not been investigated.
Kyung-Jun, Jang, Gi-Sun, Kwon, Jin-Woo, Jeong, Cheol-Hong, Kim, Hyun-Min, Yoon, Gi-Young, Kim, Jung-Hyun, Shim, Sung-Kwon, Moon, Wun-Jae, Kim, Yung Hyun, Choi   +9 more
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Acute Exercise Regulates hTERT Gene Expression and Alternative Splicing in the hTERT-BAC Transgenic Mouse Model

Medicine & Science in Sports & Exercise, 2022
ABSTRACT Introduction Aerobic exercise maintains telomere length through increased human telomerase reverse transcriptase (hTERT) expression and telomerase enzyme activity. The impact of acute exercise on hTERT alternative splicing (AS) is unknown. Purpose This study aimed
Aaron L, Slusher, Jeongjin Jj, Kim, Mark, Ribick, Andrew T, Ludlow   +3 more
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hTERT genetic variation in depression

Journal of Affective Disorders, 2016
Telomeres are protective DNA-protein complexes forming the chromosome ends. TL differs between tissues. Shorter telomere length (TL) in blood leukocytes (LTL) has been associated with major depression, and with previous exposure to childhood adversity. TL studies on non-invasively sampled salivary DNA are less common.
Ya Bin, Wei, Lina, Martinsson, Jia Jia, Liu, Yvonne, Forsell, Martin, Schalling, Lena, Backlund, Catharina, Lavebratt   +6 more
openaire   +2 more sources