Results 221 to 230 of about 28,110 (249)
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Molecular Cancer Therapeutics, 2015
Abstract Background: There is limited information of the role of hTERT methylation, hTERT expression and their association with type specific HPV infections in patients with invasive cervical cancer Objective: To analyze the possible association between methylation status of the hTERT promoter gene, hTERT expression and ...
Pablo Moreno-Acosta +7 more
openaire +1 more source
Abstract Background: There is limited information of the role of hTERT methylation, hTERT expression and their association with type specific HPV infections in patients with invasive cervical cancer Objective: To analyze the possible association between methylation status of the hTERT promoter gene, hTERT expression and ...
Pablo Moreno-Acosta +7 more
openaire +1 more source
GeroScience
Telomere shortening occurs with aging in immune cells and may be related to immunosenescence. Exercise can upregulate telomerase activity and attenuate telomere shortening in immune cells, but it is unknown if exercise impacts other immune tissues such as the thymus. This study aimed to examine human telomerase reverse transcriptase (hTERT) alternative
Jeongjin J. Kim +4 more
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Telomere shortening occurs with aging in immune cells and may be related to immunosenescence. Exercise can upregulate telomerase activity and attenuate telomere shortening in immune cells, but it is unknown if exercise impacts other immune tissues such as the thymus. This study aimed to examine human telomerase reverse transcriptase (hTERT) alternative
Jeongjin J. Kim +4 more
openaire +2 more sources
KLF4 signalling in carcinogenesis and epigenetic regulation of hTERT
Medical Hypotheses, 2018Gene expression is crucial and tightly regulated to steer the development, differentiation, proliferation and even apoptosis of a cell. Each cell and tissue type shows a unique repertoire of transcription factors. Tissue micro-environmental regulation of epigenetic signature of a gene has been documented in many cases.
Suresh Singh, Yadav +2 more
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[Proliferation and hTERT expression in neuroblastoma].
Der Pathologe, 2004Transcription of the catalytic subunit of telomerase, human Telomerase Reverse Transcriptase (hTERT), and increased tumor cell proliferation are powerful prognostic factors in neuroblastoma. We therefore investigated their relationship in a large group of neuroblastomas.RT-PCR analysis was used to discriminate between the various hTERT transcripts ...
M, Krams, P, Rudolph, D, Harms
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Cancer Research, 2018
Abstract The analysis of expression of the hTERT protein, the methylation status of the hTERT gene as the type of HPV infection, will contribute to deepen the role played by HPV infection in the expression and methylation of hTERT. The study included a group of one hundred fifty-five samples of women with squamous cell carcinomas of the ...
Pablo Moreno-Acosta +8 more
openaire +1 more source
Abstract The analysis of expression of the hTERT protein, the methylation status of the hTERT gene as the type of HPV infection, will contribute to deepen the role played by HPV infection in the expression and methylation of hTERT. The study included a group of one hundred fifty-five samples of women with squamous cell carcinomas of the ...
Pablo Moreno-Acosta +8 more
openaire +1 more source
Yi chuan xue bao = Acta genetica Sinica, 2003
The mechanism of telomerase activation is still not clear till now. In order to understand the expressional mode of telomerase and the mechanism of telomerase activation in laryngeal carcinogenesis, we cloned a fragment of hTERT cDNA and prepared a monoclonal antibody against hTERT. We performed immuno-histochemical staining in laryngeal cancer tissues
Guang-Bin, Qiu +6 more
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The mechanism of telomerase activation is still not clear till now. In order to understand the expressional mode of telomerase and the mechanism of telomerase activation in laryngeal carcinogenesis, we cloned a fragment of hTERT cDNA and prepared a monoclonal antibody against hTERT. We performed immuno-histochemical staining in laryngeal cancer tissues
Guang-Bin, Qiu +6 more
openaire +1 more source
Alternative splicing is a developmental switch for hTERT expression
Molecular Cell, 2021Michael Shen +2 more
exaly