Results 1 to 10 of about 24,253,174 (229)

HTLV-1: Regulating the Balance Between Proviral Latency and Reactivation [PDF]

Frontiers in Microbiology, 2018
HTLV-1 plus-strand transcription begins with the production of doubly-spliced tax/rex transcripts, the levels of which are usually undetectable in freshly isolated peripheral blood mononuclear cells (PBMCs) from HTLV-1-infected individuals.
Anurag Kulkarni, Charles R. M. Bangham
core   +10 more sources

High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. [PDF]

PLoS Neglected Tropical Diseases, 2013
BackgroundHuman T-cell lymphotropic virus type 1 (HTLV-1) infection can increase the risk of developing skin disorders. This study evaluated the correlation between HTLV-1 proviral load and CD4(+) and CD8(+) T cells count among HTLV-1 infected ...
Renata Okajima, Augusto C P Oliveira, Jerusa Smid, Jorge Casseb, Jose Antonio Sanches   +4 more
doaj   +9 more sources

Epidemiological Aspects and World Distribution of HTLV-1 Infection

Frontiers in Microbiology, 2012
The human T-cell leukemia virus type 1 (HTLV-1), identified as the first human oncogenic retrovirus 30 years ago, is not an ubiquitous virus. HTLV-1 is present throughout the world, with clusters of high endemicity located often nearby areas where the ...
Antoine eGessain, Antoine eGessain, Antoine eGessain, Antoine eGessain, Olivier eCassar, Olivier eCassar   +5 more
doaj   +2 more sources

Dolutegravir use is related to lower HTLV-1 proviral load in people co-infected by HIV-1 [PDF]

Communications Medicine
Background Infection by human T-cell lymphotropic virus type 1 (HTLV-1) affects millions of people worldwide and causes severe diseases. To date, no specific treatment is available for HTLV infection. The purpose of this study was to determine the impact
Tatiana Fernandez, María B. Arriaga, Rafaela Mayoral, Eduardo M. Netto, Carlos Brites   +4 more
doaj   +2 more sources

HTLV-1 Infection and Rheumatic Diseases

Frontiers in Microbiology, 2020
Some major research and clinical questions about human T-cell leukemia virus type 1 (HTLV-1) infection and rheumatic diseases remain: (1) Does HTLV-1 infection cause rheumatic diseases?
Kunihiko Umekita, Akihiko Okayama
doaj   +2 more sources

Geographic distribution, clinical epidemiology and genetic diversity of the human oncogenic retrovirus HTLV-1 in Africa, the world’s largest endemic area

Frontiers in Immunology, 2023
The African continent is considered the largest high endemic area for the oncogenic retrovirus HTLV-1 with an estimated two to five million infected individuals.
A. Gessain, Jill-Léa Ramassamy, Philippe V. Afonso, O. Cassar   +3 more
semanticscholar   +1 more source

HIV-1 and HTLV-1 Transmission Modes: Mechanisms and Importance for Virus Spread

Viruses, 2022
So far, only two retroviruses, human immunodeficiency virus (HIV) (type 1 and 2) and human T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans. Both viruses mainly infect CD4+ T lymphocytes.
S. Kalinichenko, D. Komkov, D. Mazurov
semanticscholar   +1 more source

HTLV-1 and Co-infections

Frontiers in Medicine, 2022
Human T lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes lifelong T-cell infection in humans, impacting the host immune response. This virus causes a range of clinical manifestations, from inflammatory conditions, including neuronal damage (
Carolina Rosadas, G. Taylor
semanticscholar   +1 more source

The tax-inducible actin-bundling protein fascin is crucial for release and cell-to-cell transmission of human T-cell leukemia virus type 1 (HTLV-1) [PDF]

, 2016
The delta-retrovirus Human T-cell leukemia virus type 1 (HTLV-1) preferentially infects CD4(+) T-cells via cell-to-cell transmission. Viruses are transmitted by polarized budding and by transfer of viral biofilms at the virological synapse (VS ...
Gettemans, Jan, Gross, Christine, Kalmer, Martina, Millen, Sebastian, Thoma-Kress, Andrea K, Wiesmann, Veit, Wittenberg, Thomas   +6 more
core   +15 more sources

PREVALENCE OF HIV-1/HTLV-1 CO-INFECTION AND BEHAVIORAL RISK AMONG PEOPLE LIVING WITH HIV IN BELO HORIZONTE, BRAZIL

Revista de Salud Pública, 2023
Objective: To analyze the prevalence of HIV-1 and HTLV-1 co-infection and risk behavioral for sexually transmitted infections (STIs) and the quality of life among people living with HIV-1 (PL-HIV-1).
Poliane Cristina Vertêlo, Alexandre Braga Miranda, Ludimila Labanca, Ana Lúcia Borges-Starling, Cláudio Daniel Cerdeira, Carlos Felipe Nogueira, Denise Utsch Gonçalves   +6 more
doaj   +1 more source