Results 41 to 50 of about 24,253,245 (291)
Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission [PDF]
, 2013 Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-
Afonso, PV +7 more
core +7 more sources
Journal of Clinical Pathology, 2000 Human T lymphotropic virus type 1 (HTLV-1) causes disabling and fatal diseases, yet there is no vaccine, no satisfactory treatment, and no means of assessing the risk of disease or prognosis in infected people. Recent research on the molecular virology and immunology of HTLV-1 shows the importance of the host's immune response in reducing the risk of ...
openaire +2 more sources
Regulation of HTLV-1 transformation [PDF]
Bioscience Reports, 2022 AbstractHuman T-cell leukemia virus type 1 (HTLV-1) is the only identified oncogenic human retrovirus. HTLV-1 infects approximately 5–10 million people worldwide and is the infectious cause of adult T-cell leukemia/lymphoma (ATL) and several chronic inflammatory diseases, including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP ...
Kyle J. Ernzen, Amanda R. Panfil
openaire +2 more sources
Effect of HTLV-1 Infection on the Clinical Course of Patients with Rheumatoid Arthritis
Viruses, 2022 Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The effects of HTLV-1 on health are not fully elucidated.
Kunihiko Umekita
doaj +1 more source
Prevalence and risk factors for Human T-Lymphotropic Virus Type 1 (HTLV-1) among maintenance hemodialysis patients [PDF]
, 2017 BACKGROUND: Infection with the human T-cell lymphotropic virus type 1 (HTLV-1), although asymptomatic in most cases, can lead to potentially grave consequences, such as adult T-cell leukemia-lymphoma and HTLV-1-associated myelopathy / tropical spastic ...
Angiolina Kraychete +7 more
core +1 more source
The roles of acquired and innate immunity in human T-cell leukemia virus type 1-mediated diseases
Frontiers in Microbiology, 2012 Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis in small subsets of HTLV-1-carriers.
Mari eKannagi +4 more
doaj +1 more source
Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]
, 2016 Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra +10 more
core +2 more sources
Mother-to-Child HTLV-1 Transmission: Unmet Research Needs
Frontiers in Microbiology, 2019 Mother-to-child transmission (MTCT) of Human T-cell lymphotropic virus type 1 (HTLV-1) causes lifelong infection. At least 5–10 million individuals worldwide are currently living with HTLV-1.
Carolina Rosadas, G. Taylor
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The balance of proinflammatory and anti-inflammatory cytokines is important for tissue homeostasis. It is well known that excessive production of proinflammatory cytokines promotes tumor development.
Y. Higuchi +6 more
semanticscholar +1 more source
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication [PDF]
The Journal of Immunology, 2017 Abstract Human T lymphotropic virus type 1 (HTLV-1) belongs to the deltaretrovirus family and has been linked to multiple diseases. However, the innate host defense against HTLV-1 is unclear. In this study, we report that the expression of Ku70, a known DNA sensor against DNA viruses, could be induced by HTLV-1 infection in HeLa, PMA ...
Jie Wang +9 more
openaire +2 more sources