Results 71 to 80 of about 24,253,245 (291)

Role of HIV RNA structure in recombination and speciation: romping in purine A, keeps HTLV away

, 2013
Extreme enrichment of the human immunodeficiency virus (HIV-1) RNA genome for the purine A parallels the mild purine-loading of the RNAs of most organisms.
Forsdyke, Donald R.
core   +1 more source

Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1

Wellcome Open Research, 2017
Background: The human leukaemia virus HTLV-1 expresses essential accessory genes that manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, tax and hbz, also promote proliferation of the infected cell, and both genes are ...
Martin R Billman, D. Rueda, C. Bangham
semanticscholar   +1 more source

The Global Burden of Leukemia, 1990–2021: A Systematic Analysis of Prevalence, DALYs, and Risk Factors From the Global Burden of Disease Study

Med Research, EarlyView.
Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu, Haini Zhang, Shuang Luo, Xiangmei Zhang, Mei Tan, Jinmei Chen, Pei Huang, Yan Chen, Zuochen Du   +8 more
wiley   +1 more source

Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease

Retrovirology, 2005
Background Human T-lymphotropic virus type 1 (HTLV-1) proviral load is related to the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and has also been shown to be elevated in the peripheral blood in HTLV-1-infected ...
Olindo Stéphane, Lagathu Gisèle, Dantin Fabienne, Lézin Agnès, Yakova Maria, Jean-Baptiste Georges, Arfi Serge, Césaire Raymond   +7 more
doaj   +1 more source

Effect of pulsed methylprednisolone on pain, in patients with HTLV-1-associated myelopathy [PDF]

, 2016
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immune mediated myelopathy caused by the human T-lymphotropic virus type 1 (HTLV-1). The efficacy of treatments used for patients with HAM/TSP is uncertain.
Adonis, A, Buell, KG, Demontis, MA, Dhasmana, D, Haddow, J, Martin, F, Puri, A, Short, CL, Taylor, GP   +8 more
core   +1 more source

HTLV-1, the Other Pathogenic Yet Neglected Human Retrovirus: From Transmission to Therapeutic Treatment

Viruses, 2017
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the virology scene, not only because they were the first human retroviruses ...
Nicolas Futsch, R. Mahieux, H. Dutartre
semanticscholar   +1 more source

Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis

Journal of Neurovirology, 2020
Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Satoshi Nozuma, R. Kubota, S. Jacobson
semanticscholar   +1 more source

HTLV-1 pathogenesis mediated by HTLV-1 bZIP factor

Uirusu, 2012
HTLV-1 is a retrovirus associated with human diseases, such as ATL or HAM/TSP. More than thirty years have passed since HTLV-1 was discovered, but the precise mechanism of HTLV-1 pathogenesis still remains elusive. HTLV-1 bZIP factor (HBZ) was reported ten years ago as a viral gene encoded in the minus strand of HTLV-1.
openaire   +3 more sources

T‐Cell Signaling Pathways, Including Exhaustion, Predominate in Unhealthy Visceral and Subcutaneous Adipose Tissues

Obesity, EarlyView.
ABSTRACT Objective Obesity is an imperfect correlate of metabolic health. Visceral adipose tissue (VAT) characteristics are considered determinants of poor health and subcutaneous adipose tissue (SAT) considered protective. There is a gap in knowledge regarding shared vs.
Sobha Puppala, Alyssa R. Hamann, Christina M. Stevens, Alistaire Ruggiero, Laura A. Cox, Kylie Kavanagh   +5 more
wiley   +1 more source

Cytokine Networks Dysregulation during HTLV-1 Infection and Associated Diseases

Viruses, 2018
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and of a malignant lymphoproliferation, called the adult T-cell leukemia ...
Nicolas Futsch, Gabriela Prates, R. Mahieux, J. Casseb, H. Dutartre   +4 more
semanticscholar   +1 more source