Results 91 to 100 of about 100,698 (279)
Experimental Biology and MedicineNeurological pain (NP) is always accompanied by symptoms of depression, which seriously affects physical and mental health. In this study, we identified the common hub genes (Co-hub genes) and related immune cells of NP and major depressive disorder (MDD)
Jinjing Hu +17 more
doaj +1 more source
BMC Medical Genomics, 2021 Co-expression network may contribute to better understanding molecular interaction patterns underlying cellular processes. To explore microRNAs (miRNAs) expression patterns correlated with AF, we performed weighted gene co-expression network analysis ...
Qiang Qu +6 more
doaj +1 more source
Large-scale inference and graph theoretical analysis of gene-regulatory networks in B. stubtilis
, 2006 We present the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B. subtilis from experimentally obtained, yet mathematically underdetermined microchip array data.
Albert +42 more
core +1 more source
Hub genes of stroke identified by weighted gene co-expression network analysis [PDF]
, 2019 Abstract Background Microarray-based gene expression profiling has been widely used in biomedical research. Weighted gene co-expression network analysis (WGCNA) can link microarray data directly to clinical traits and to identify rules for predicting pathological stage and prognosis of disease, it has been found useful in many biological ...
Junhong Li +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Frontiers in Genetics, 2021 AimsIn the cancer-related research field, there is currently a major need for a greater number of valuable biomarkers to predict the prognosis of hepatocellular carcinoma (HCC).
Huaping Chen +9 more
doaj +1 more source
Gene's hubs in retinal diseases: A retinal disease network [PDF]
Heliyon, 2018 Retinal diseases associated with the dysfunction or death of photoreceptors are a major cause of blindness around the world, improvements in genetics tools, like next generation sequencing (NGS) allows the discovery of genes and genetic changes that lead to many of those retinal diseases.
J.M. Lázaro-Guevara +7 more
openaire +3 more sources
Comprehensive Analysis of Hub Genes In Prostate Cancer [PDF]
, 2021 Abstract Abstract：The present study aims to explore the involvement of hub genes in prostate cancer (PCa). Three series were used in this study: GSE46602, GSE5377, and GSE8511 from GPL570 platform in the Gene Expression Omnibus and the other resources from The Cancer Genome Atlas and UCSC Xena. A total of 47 differentially expressed genes (DEGs)
Zhi Yang, JUN MI
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition [PDF]
, 2018 Joubert syndrome (JBTS) is a genetically heterogeneous autosomal recessive neurodevelopmental ciliopathy. We investigated further the underlying genetic etiology of Joubert syndrome by studying two unrelated families in whom JBTS was not associated ...
Alhashem, Amal +18 more
core +1 more source