Results 71 to 80 of about 8,236,393 (357)

GWAS and WGCNA uncover hub genes controlling salt tolerance in maize (Zea mays L.) seedlings

open access: yesTheoretical and Applied Genetics, 2021
Two hub genesGRMZM2G075104andGRMZM2G333183involved in salt tolerance were identified by GWAS and WGCNA. Furthermore, they were verified to affect salt tolerance by candidate gene association analysis.
Lang-Lang Ma   +11 more
semanticscholar   +1 more source

united-manufacturing-hub/united-manufacturing-hub: v0.9.16

open access: yes, 2023
<h2>What's Changed</h2> <ul> <li>fix: changed links from docker to GHCR by @Vermuden in https://github.com/united-manufacturing-hub/united-manufacturing-hub/pull/1532</li> <li>build(deps): bump golang.org/x/crypto from
kruegeralex   +20 more
core   +2 more sources

Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis

open access: yesAnalytical Cellular Pathology, 2022
Background. To investigate the relationship between primary ovarian insufficiency and autophagy, we detected and got the expression profile of human granulosa cell line SVOG, which was with or without LPS induced. The expression profile was analyzed with
Siji Lv, Jiani Sun, Jing Sun
doaj   +1 more source

Hub Genes, Diagnostic Model, and Predicted Drugs Related to Iron Metabolism in Alzheimer's Disease

open access: yesFrontiers in Aging Neuroscience, 2022
Alzheimer's disease (AD), the most common neurodegenerative disease, remains unclear in terms of its underlying causative genes and effective therapeutic approaches. Meanwhile, abnormalities in iron metabolism have been demonstrated in patients and mouse
Xuefeng Gu   +8 more
semanticscholar   +1 more source

Weighted Gene Co-Expression Network Analysis Combined with Machine Learning Validation to Identify Key Modules and Hub Genes Associated with SARS-CoV-2 Infection

open access: yesJournal of Clinical Medicine, 2021
The coronavirus disease-2019 (COVID-19) pandemic has caused an enormous loss of lives. Various clinical trials of vaccines and drugs are being conducted worldwide; nevertheless, as of today, no effective drug exists for COVID-19.
H. Karami   +14 more
semanticscholar   +1 more source

Integrated analysis of hub genes and miRNA- transcription factor-hub gene interaction network in necrotizing enterocolitis

open access: yes, 2023
Abstract Background The aim of this study was to identify hub genes, related transcription factors (TFs) and miRNAs from the miRNA–TF–gene interaction network in necrotizing enterocolitis (NEC). Methods Three expression data sets from GEO database that compared NEC with surgical negative controls were used to calculate differentially ...
Yuqian Su   +6 more
openaire   +1 more source

Enhanced construction of gene regulatory networks using hub gene information [PDF]

open access: yesBMC Bioinformatics, 2017
Gene regulatory networks reveal how genes work together to carry out their biological functions. Reconstructions of gene networks from gene expression data greatly facilitate our understanding of underlying biological mechanisms and provide new opportunities for biomarker and drug discoveries.
Donghyeon Yu   +4 more
openaire   +2 more sources

Hub genes and their key effects on prognosis of Burkitt lymphoma

open access: yesWorld Journal of Clinical Oncology, 2023
Burkitt lymphoma (BL) is an exceptionally aggressive malignant neoplasm that arises from either the germinal center or post-germinal center B cells. Patients with BL often present with rapid tumor growth and require high-intensity multi-drug therapy combined with adequate intrathecal chemotherapy prophylaxis, however, a standard treatment program for ...
Xu, Yan-Feng   +3 more
openaire   +2 more sources

Co-expression Network Analysis Reveals Novel Genes Underlying Alzheimer’s Disease Pathogenesis

open access: yesFrontiers in Aging Neuroscience, 2020
Background: The pathogenesis of Alzheimer’s disease (AD) remains to be elucidated. This study aimed to identify the hub genes in AD pathogenesis and determine their functions and pathways.Methods: A co-expression network for an AD gene dataset with 401 ...
Rui-ting Hu   +6 more
doaj   +1 more source

Identification of hub genes for early detection of bone metastasis in breast cancer

open access: yesFrontiers in Endocrinology, 2022
Background Globally, among all women, the most frequently detected and diagnosed and the most lethal type of cancer is breast cancer (BC). In particular, bone is one of the most frequent distant metastases 24in breast cancer patients and bone metastasis ...
Zi-Tong Zhao   +6 more
semanticscholar   +1 more source

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