Results 91 to 100 of about 5,790,030 (310)

Hub genes, a diagnostic model, and immune infiltration based on ferroptosis-linked genes in schizophrenia

IBRO Neuroscience Reports
Background Schizophrenia (SCZ) is a prevalent and serious mental disorder, and the exact pathophysiology of this condition is not fully understood. In previous studies, it has been proven that ferroprotein levels are high in SCZ.
Kun Lian, Yongmei Li, Wei Yang, Jing Ye, Hongbing Liu, Tianlan Wang, Guangya Yang, Yuqi Cheng, Xiufeng Xu   +8 more
semanticscholar   +1 more source

Integrated Analysis of Hub Genes and miRNAs in Dilated Cardiomyopathy [PDF]

BioMed Research International, 2020
Purpose. The aim of this study is to identify hub genes and miRNAs by the miRNA‐mRNA interaction network in dilated cardiomyopathy (DCM) disease. Methods. The differentially expressed miRNAs (DEMis) and mRNAs (DEMs) were selected using data of DCM patients downloaded from the GEO database (GSE112556 and GSE3585). Gene Ontology (GO) pathway analysis and
Kai Huang, Shuyan Wen, Jiechun Huang, Fangrui Wang, Liewen Pang, Yiqing Wang, Xiaotian Sun   +6 more
openaire   +2 more sources

Evaluation of genes and molecular pathway related pathogenesis of endometriosis: A bioinformatics approach

Informatics in Medicine Unlocked, 2023
Objective: Although recent studies have focused on the role of genes in the pathogenesis of endometriosis, the investigation of genes and molecular pathways involved in the pathogenesis of endometriosis with a bioinformatics approach has not been ...
Mahin Khalilzadeh Seivani, Noushin Modabber, Marzieh Shadpirouz, Bahareh Shateri Amiri, Parvane Bahoorzahi, Sahar Bahraminia   +5 more
doaj   +1 more source

Identification of key hub genes in knee osteoarthritis through integrated bioinformatics analysis

Scientific Reports
Knee osteoarthritis (KOA) is a common chronic joint disease globally. Synovial inflammation plays a pivotal role in its pathogenesis, preceding cartilage damage.
Lilei Xu, Jiaqi Ma, Chuanlong Zhou, Zhe Shen, Kean Zhu, Xuewen Wu, Yang Chen, Ting Chen, Xianming Lin   +8 more
semanticscholar   +1 more source

Integrated Bioinformatics-Based Analysis of Hub Genes and the Mechanism of Immune Infiltration Associated With Acute Myocardial Infarction

Frontiers in Cardiovascular Medicine, 2022
Background Acute myocardial infarction (AMI) is a fatal disease that causes high morbidity and mortality. It has been reported that AMI is associated with immune cell infiltration.
Yanze Wu, Ting Jiang, Jinghai Hua, Zhiping Xiong, Hui Chen, Lei Li, Jing-Wen Peng, Wenjun Xiong   +7 more
semanticscholar   +1 more source

Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics

Frontiers in Cell and Developmental Biology, 2022
An improved understanding of the molecular mechanism of colorectal adenocarcinoma is necessary to predict the prognosis and develop new target gene therapy strategies. This study aims to identify hub genes associated with colorectal adenocarcinoma and further analyze their prognostic significance. In this study, The Cancer Genome Atlas (TCGA) COAD-READ
Yang Liu, Lanlan Chen, Xiangbo Meng, Shujun Ye, Lianjun Ma   +4 more
openaire   +3 more sources

The Identification and Validation of Hub Genes Associated with Acute Myocardial Infarction Using Weighted Gene Co-Expression Network Analysis

Journal of Cardiovascular Development and Disease, 2022
Acute myocardial infarction (AMI), one of the most severe and fatal cardiovascular diseases, remains the main cause of mortality and morbidity worldwide.
Junqiang Xue, Lu Chen, Hao Cheng, Xiaoyue Song, Yuekai Shi, Linnan Li, Rende Xu, Q. Qin, Jianying Ma, Junbo Ge   +9 more
semanticscholar   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Identification of Hub Genes Associated With Immune Infiltration and Predict Prognosis in Hepatocellular Carcinoma via Bioinformatics Approaches

Frontiers in Genetics, 2021
AimsIn the cancer-related research field, there is currently a major need for a greater number of valuable biomarkers to predict the prognosis of hepatocellular carcinoma (HCC).
Huaping Chen, Junrong Wu, Liuyi Lu, Zuojian Hu, Xi Li, Li Huang, Xiaolian Zhang, Mingxing Chen, Xue Qin, Li Xie   +9 more
doaj   +1 more source

Identification of Novel Hub Genes Associated with Psoriasis Using Integrated Bioinformatics Analysis

International Journal of Molecular Sciences, 2022
Psoriasis is a chronic, prolonged, and recurrent inflammatory skin disease and the current therapeutics can only alleviate the symptoms rather than cure it completely.
Qi Yue, Z. Li, Qi Zhang, Quan-xin Jin, Xinyuan Zhang, Guihua Jin   +5 more
semanticscholar   +1 more source