Results 101 to 110 of about 8,236,393 (357)

The parenting hub of the hypothalamus is a focus of imprinted gene action

PLOS Genetics, 2023
Imprinted genes are subject to germline epigenetic modification resulting in parental-specific allelic silencing. Although genomic imprinting is thought to be important for maternal behaviour, this idea is based on serendipitous findings from a small number of imprinted genes. Here, we undertook an unbiased systems biology approach, taking advantage of
Matthew J. Higgs, Anna E. Webberley, Alasdair J. Allan, Moaz Talat, Rosalind M. John, Anthony R. Isles   +5 more
openaire   +3 more sources

Evaluation of genes and molecular pathway related pathogenesis of endometriosis: A bioinformatics approach

Informatics in Medicine Unlocked, 2023
Objective: Although recent studies have focused on the role of genes in the pathogenesis of endometriosis, the investigation of genes and molecular pathways involved in the pathogenesis of endometriosis with a bioinformatics approach has not been ...
Mahin Khalilzadeh Seivani, Noushin Modabber, Marzieh Shadpirouz, Bahareh Shateri Amiri, Parvane Bahoorzahi, Sahar Bahraminia   +5 more
doaj   +1 more source

Prediction of interactomic hub genes in PBMC cells in type 2 diabetes mellitus, dyslipidemia, and periodontitis

BMC Oral Health
In recent years, the complex interplay between systemic health and oral well-being has emerged as a focal point for researchers and healthcare practitioners.
P. Yadalam, Deepavalli Arumuganainar, V. Ronsivalle, M. Di Blasio, A. Badnjević, M. Marrapodi, G. Cervino, G. Minervini   +7 more
semanticscholar   +1 more source

Identification of hub genes associated with acute kidney injury induced by renal ischemia–reperfusion injury in mice

Frontiers in Physiology, 2022
Background: Acute kidney injury (AKI) is a severe clinical syndrome, and ischemia–reperfusion injury is an important cause of acute kidney injury. The aim of the present study was to investigate the related genes and pathways in the mouse model of acute ...
Sheng-De He, Li-Li He, Fang-Ran Yan, Junda Li, Xiaoting Liao, Mao-Yao Ling, Ren Jing, Ling-Hui Pan   +7 more
semanticscholar   +1 more source

Summary of functions of hub genes.

, 2021
Summary of functions of hub genes.
Chuansen Lu (11473345), Dan Huang (122168), Zhongyan Zhao (11254731), Yike Zhu (11473342)   +3 more
core   +1 more source

Discovering New Hub Genes of Dilated Cardiomyopathy

ESC Heart Failure
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified.
Jun-Yan Zhu, Yu Han, Jing-Yu Yang, De-Ping Wang, Li-Juan Gao, Teng Sun, Yan-Lin Feng, Zhong-Mei He, Bin Zhou, Ji-Min Cao   +9 more
openaire   +3 more sources

Identification and Validation of Hub Genes in the Stenosis of Arteriovenous Fistula

Journal of Personalized Medicine, 2023
Arteriovenous fistula (AVF) is the most widely used hemodialysis vascular access in China. However, stenosis of the AVF limits its use. The mechanism of AVF stenosis is currently unknown. Therefore, the purpose of our study was to explore the mechanisms of AVF stenosis. In this study, we identified the differentially expressed genes (DEGs) based on the
Yu Li, Yue Chen, Wenhao Cui, Jukun Wang, Xin Chen, Chao Zhang, Linzhong Zhu, Chunjing Bian, Tao Luo   +8 more
openaire   +2 more sources

Hub genes, a diagnostic model, and immune infiltration based on ferroptosis-linked genes in schizophrenia

IBRO Neuroscience Reports
Background Schizophrenia (SCZ) is a prevalent and serious mental disorder, and the exact pathophysiology of this condition is not fully understood. In previous studies, it has been proven that ferroprotein levels are high in SCZ.
Kun Lian, Yongmei Li, Wei Yang, Jing Ye, Hongbing Liu, Tian-Lan Wang, Guangya Yang, Yu-Qi Cheng, Xiu-Feng Xu   +8 more
semanticscholar   +1 more source

Functional roles of 15 hub genes.

, 2022
Functional roles of 15 hub genes.
Huanqing Liu (11214000), Jun Lyu (6201101), Tingting Li (10553), Chunsheng Dong (12005639)   +3 more
core   +1 more source

Identifying hub genes of calcific aortic valve disease and revealing the immune infiltration landscape based on multiple WGCNA and single-cell sequence analysis

Frontiers in Immunology, 2022
BackgroundCalcific aortic valve disease (CAVD) is a progressive fibrocalcific disease that can be treated only through valve replacement. This study aimed to determine the role of hub genes and immune cell infiltration in CAVD progression.MethodsIn this ...
Kan Wang, Qiang Zheng, Xing Liu, BingChuan Geng, NianGuo Dong, JiaWei Shi   +5 more
doaj   +1 more source