Results 81 to 90 of about 135,319 (315)

Discovering New Hub Genes of Dilated Cardiomyopathy

open access: yesESC Heart Failure
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified.
Jun-Yan Zhu   +9 more
openaire   +3 more sources

Identification of hub genes associated with spermatogenesis by bioinformatics analysis

open access: yesScientific Reports, 2023
AbstractSpermatogenesis is a complex process related to male infertility. Till now, the critical genes and specific mechanisms have not been elucidated clearly. Our objective was to determine the hub genes that play a crucial role in spermatogenesis by analyzing the differentially expressed genes (DEGs) present in non-obstructive azoospermia (NOA ...
Shuang Liu   +7 more
openaire   +3 more sources

Autoimmune Disease-Related Hub Genes are Potential Biomarkers and Associated with Immune Microenvironment in Endometriosis

open access: yes, 2023
Yin-Ting Yang,1,2,* Xi-Ya Jiang,1,2,* Hong-Liang Xu,3,* Guo Chen,1,2,* Sen-Lin Wang,4 He-Ping Zhang,3 Lin Hong,1,2 Qin-Qin Jin,1,2 Hui Yao,1,2 Wei-Yu Zhang,1,2 Yu-Ting Zhu,1,2 Jie Mei,1,2 Lu Tian,1,2 Jie Ying,1,2 Jing-Jing Hu,5 Shu-Guang ...
Hong L   +15 more
core  

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Significance of hub genes and immune cell infiltration identified by bioinformatics analysis in pelvic organ prolapse [PDF]

open access: yesPeerJ, 2020
Objective Pelvic organ prolapse (POP) refers to the decline of pelvic organ position and dysfunction caused by weak pelvic floor support. The aim of the present study was to screen the hub genes and immune cell infiltration related to POP disease ...
Ying Zhao   +3 more
doaj   +2 more sources

Identifying Immune Cell Infiltration and Hub Genes During the Myocardial Remodeling Process After Myocardial Infarction

open access: yes, 2023
Yuan Tian,1,* Zilin Wang,2,* Feng Liang,3,* Yi Wang1 1Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People’s Republic of China; 2Department of Radiology, Shanghai ...
Liang F, Tian Y, Wang Y, Wang Z
core  

Cancer hub genes of the cancer gene relationship network.

open access: yes, 2021
Type 1: hub genes enriched for only gained links; Type 2: hub genes enriched for only lost links; Type 3: hub genes enriched for both gained and lost links. (A) The number of three different types of cancer hub genes.
Kui Chen (157443)   +4 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics

open access: yesFrontiers in Cell and Developmental Biology, 2022
An improved understanding of the molecular mechanism of colorectal adenocarcinoma is necessary to predict the prognosis and develop new target gene therapy strategies. This study aims to identify hub genes associated with colorectal adenocarcinoma and further analyze their prognostic significance. In this study, The Cancer Genome Atlas (TCGA) COAD-READ
Yang Liu   +4 more
openaire   +3 more sources

Bioinformatics Based Drug Repurposing Approach for Breast and Gynecological Cancers: RECQL4/FAM13C Genes Address Common Hub Genes and Drugs [PDF]

open access: yes
Objective: The prevalence of breast cancer and gynaecological cancers is high, and these cancer types can occur consecutively as secondary cancers. The aim of our study is to determine the genes commonly expressed in these cancers and to identify the ...
Gizem Ayna Duran
core   +1 more source

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