Results 61 to 70 of about 8,236,393 (357)

Identification of the hub genes associated with prostate cancer tumorigenesis

Frontiers in Oncology, 2023
Introduction Prostate cancer (PCa) is one of the most common malignant tumors of the male urogenital system; however, the underlying mechanisms remain largely unclear. This study integrated two cohort profile datasets to elucidate the potential hub genes
Honghui Zhu, Qingbin Lin, Xiao-Min Gao, Xi-Xi Huang   +3 more
semanticscholar   +1 more source

List of the real hub genes identified from the PPI network of the extracted 210 CRC related hub genes.

, 2021
List of the real hub genes identified from the PPI network of the extracted 210 CRC related hub genes.
Shufang Liang (781312), Muhammad Usman (1504405), Samina Ejaz (11378800), Yasir Hameed (8939681)   +3 more
core   +1 more source

Identification of 13 Key Genes Correlated With Progression and Prognosis in Hepatocellular Carcinoma by Weighted Gene Co-expression Network Analysis

Frontiers in Genetics, 2020
Hepatocellular carcinoma (HCC) remains hard to diagnose early and cure due to a lack of accurate biomarkers and effective treatments. Hence, it is necessary to explore the tumorigenesis and tumor progression of HCC to discover new biomarkers for clinical
Yang Gu, Jun Li, Deliang Guo, Baiyang Chen, Pengpeng Liu, Yusha Xiao, Kang Yang, Zhisu Liu, Quanyan Liu   +8 more
doaj   +1 more source

Identification of the prognostic biomarkers and their correlations with immune infiltration in colorectal cancer through bioinformatics analysis and in vitro experiments

Heliyon, 2023
Colorectal cancer (CRC) is the third most diagnosed malignancy and the second leading cause of cancer death. The objective was to identify novel hub genes that were helpful for prognosis and targeted therapy in CRC. GSE23878, GSE24514, GSE41657, GSE81582
Min Guo, Xiaxi Li, Jiong Li, Baolong Li
doaj   +1 more source

Uncovering hub genes in sepsis through bioinformatics analysis

Medicine, 2023
In-depth studies on the mechanisms of pathogenesis of sepsis and diagnostic biomarkers in the early stages may be the key to developing individualized and effective treatment strategies.
Zhao Liu, Er-Yue Qiu, Bihui Yang, Yi-Qian Zeng   +3 more
semanticscholar   +1 more source

Hub genes GWAS association.

, 2022
Genetic association of hub genes with the lung related traits and lung cancer from Phenoscanner database. (DOCX)
Ramu Elango (704627), Dalal Sameer Alshaer (13905757), Kawthar Saad Alghamdi (12877940), Babajan Banaganapalli (704628), Bayan Mallah (13905751), Nuha Alrayes (3474665), Noor A. Shaik (5147717), Walaa F. Albaqami (13905754)   +7 more
core   +1 more source

Nuclear pore complexes as hubs for gene regulation [PDF]

Nucleus, 2018
Nuclear pore complexes (NPCs), the channels connecting the nucleus with the cytoplasm, are the largest protein structures of the nuclear envelope. In addition to their role in regulating nucleocytoplasmic transport, increasing evidence shows that these multiprotein structures play central roles in the regulation of gene activity.
openaire   +2 more sources

LongGeneDB: a data hub for long genes [PDF]

, 2020
ABSTRACT The human genome contains more than 4000 genes that are longer than 100 kb. These long genes require more time and resources to make a transcript than shorter genes do. Long genes have also been linked to various human diseases.
Sohyun Moon, Yura Kim, Mariam Naghavi, Jerry Yingtao Zhao   +3 more
openaire   +1 more source

Gene Expression Microarray Data Identify Hub Genes Involved in Osteoarthritis

Frontiers in Genetics, 2022
The present study was performed to explore the underlying molecular mechanisms and screen hub genes of osteoarthritis (OA) via bioinformatics analysis. In total, twenty-five OA synovial tissue samples and 25 normal synovial tissue samples were derived from three datasets, namely, GSE55457, GSE55235, and GSE1919, and were used to identify the ...
Jian Zhou, Dazhi Zou, Rongjun Wan, Rongjun Wan, Jie Liu, Qiong Zhou, Zhen Zhou, Wanchun Wang, Cheng Tao, Tang Liu   +9 more
openaire   +3 more sources

Identification of novel potential biomarkers in infantile hemangioma via weighted gene co-expression network analysis

BMC Pediatrics, 2022
Background Infantile hemangioma (IH) is the most common benign tumor in children and is characterized by endothelial cells proliferation and angiogenesis. Some hub genes may play a critical role in angiogenesis. This study aimed to identify the hub genes
Bin Xie, Xiongming Zhou, Jiaxuan Qiu
doaj   +1 more source