Results 61 to 70 of about 2,288,692 (305)

Genes-miRNAs interaction network.

, 2022
Hexagons represent hub genes; circle nodes represent miRNAs associated with hub genes.
Yun Chen (279569), Ying Zhao (16546), Chenyun Miao (10668003), Xiaojie Fang (8319717), Qin Zhang (58638), Ruye Wang (3986681)   +5 more
core   +1 more source

Identification of potential ferroptosis-associated biomarkers in rheumatoid arthritis

Frontiers in Immunology, 2023
BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by inflammation and gradual joint degeneration, resulting in function disability.
Xu He, Xu He, Juqi Zhang, Juqi Zhang, Juqi Zhang, Mingli Gong, Yanlun Gu, Yanlun Gu, Yanlun Gu, Bingqi Dong, Xiaocong Pang, Xiaocong Pang, Chenglong Zhang, Yimin Cui, Yimin Cui, Yimin Cui   +15 more
doaj   +1 more source

The parenting hub of the hypothalamus is a focus of imprinted gene action

PLOS Genetics, 2023
Imprinted genes are subject to germline epigenetic modification resulting in parental-specific allelic silencing. Although genomic imprinting is thought to be important for maternal behaviour, this idea is based on serendipitous findings from a small number of imprinted genes. Here, we undertook an unbiased systems biology approach, taking advantage of
Matthew J. Higgs, Anna E. Webberley, Alasdair J. Allan, Moaz Talat, Rosalind M. John, Anthony R. Isles   +5 more
openaire   +3 more sources

Airport Dominance and Airline Pricing Power: An Investigation of Hub Premiums in the Chinese Domestic Market [PDF]

, 2013
Concerns on market power conferred by airport dominance and the debates of hub premiums have attracted longstanding attention from governments and academics alike.
Chen, Ruowei
core   +6 more sources

Evaluation of genes and molecular pathway related pathogenesis of endometriosis: A bioinformatics approach

Informatics in Medicine Unlocked, 2023
Objective: Although recent studies have focused on the role of genes in the pathogenesis of endometriosis, the investigation of genes and molecular pathways involved in the pathogenesis of endometriosis with a bioinformatics approach has not been ...
Mahin Khalilzadeh Seivani, Noushin Modabber, Marzieh Shadpirouz, Bahareh Shateri Amiri, Parvane Bahoorzahi, Sahar Bahraminia   +5 more
doaj   +1 more source

Discovering New Hub Genes of Dilated Cardiomyopathy

ESC Heart Failure
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified.
Jun-Yan Zhu, Yu Han, Jing-Yu Yang, De-Ping Wang, Li-Juan Gao, Teng Sun, Yan-Lin Feng, Zhong-Mei He, Bin Zhou, Ji-Min Cao   +9 more
openaire   +3 more sources

Identification and Validation of Hub Genes in the Stenosis of Arteriovenous Fistula

Journal of Personalized Medicine, 2023
Arteriovenous fistula (AVF) is the most widely used hemodialysis vascular access in China. However, stenosis of the AVF limits its use. The mechanism of AVF stenosis is currently unknown. Therefore, the purpose of our study was to explore the mechanisms of AVF stenosis. In this study, we identified the differentially expressed genes (DEGs) based on the
Yu Li, Yue Chen, Wenhao Cui, Jukun Wang, Xin Chen, Chao Zhang, Linzhong Zhu, Chunjing Bian, Tao Luo   +8 more
openaire   +2 more sources

Identification of hub genes predicting the development of prostate cancer from benign prostate hyperplasia and analyzing their clinical value in prostate cancer by bioinformatic analysis

Discover Oncology, 2022
Prostate cancer (PCa) and benign prostate hyperplasia (BPH) are commonly encountered diseases in males. Studies showed that genetic factors are responsible for the occurrences of both diseases.
Xi Chen, Junjie Ma, Chengdang Xu, Licheng Wang, Yicong Yao, Xinan Wang, Tong Zi, Cuidong Bian, Denglong Wu, Gang Wu   +9 more
doaj   +1 more source

Identifying hub genes of calcific aortic valve disease and revealing the immune infiltration landscape based on multiple WGCNA and single-cell sequence analysis

Frontiers in Immunology, 2022
BackgroundCalcific aortic valve disease (CAVD) is a progressive fibrocalcific disease that can be treated only through valve replacement. This study aimed to determine the role of hub genes and immune cell infiltration in CAVD progression.MethodsIn this ...
Kan Wang, Qiang Zheng, Xing Liu, BingChuan Geng, NianGuo Dong, JiaWei Shi   +5 more
doaj   +1 more source

Hub gene target of glioblastoma: LOX, SERPINH1 and TGFBI

Medicine, 2022
Glioblastoma (GBM) is a malignant tumor. The long-term prognosis of the patients is poor. Therefore, it is of important clinical value to further explore the pathogenesis and look for molecular markers for early diagnosis and targeted treatment.
Shuyuan Zhang, Weiwei Zhang, Bin Wu, Liang Xia, Liwen Li, Kai Jin, Yangfan Zou, Caixing Sun   +7 more
openaire   +2 more sources