Results 51 to 60 of about 135,319 (315)

Analysis of hub genes in different subnetworks.

, 2022
(A) Hub genes in Common-P. (B) Hub genes in HMI-MMI-SP. (C) Hub genes in MMI-MHCI-SP. (D) Hub genes in HMI-MHCI-SP. (E) Hub genes in HMI-SP. (F) Hub genes in MMI-SP. (G) Hub genes in MHCI-SP.
Yao Jiang (1469614), Jia-Xuan Zhang (14279440), Rong Liu (202610)   +2 more
core   +1 more source

Genes-miRNAs interaction network.

, 2022
Hexagons represent hub genes; circle nodes represent miRNAs associated with hub genes.
Yun Chen (279569), Ying Zhao (16546), Chenyun Miao (10668003), Xiaojie Fang (8319717), Qin Zhang (58638), Ruye Wang (3986681)   +5 more
core   +1 more source

Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis

Analytical Cellular Pathology, 2022
Background. To investigate the relationship between primary ovarian insufficiency and autophagy, we detected and got the expression profile of human granulosa cell line SVOG, which was with or without LPS induced. The expression profile was analyzed with
Siji Lv, Jiani Sun, Jing Sun
doaj   +1 more source

Genes-TFs interaction network.

, 2022
Hexagons represent hub genes; circle nodes represent TFs associated with hub genes.
Yun Chen (279569), Ying Zhao (16546), Chenyun Miao (10668003), Xiaojie Fang (8319717), Qin Zhang (58638), Ruye Wang (3986681)   +5 more
core   +1 more source

Co-expression Network Analysis Reveals Novel Genes Underlying Alzheimer’s Disease Pathogenesis

Frontiers in Aging Neuroscience, 2020
Background: The pathogenesis of Alzheimer’s disease (AD) remains to be elucidated. This study aimed to identify the hub genes in AD pathogenesis and determine their functions and pathways.Methods: A co-expression network for an AD gene dataset with 401 ...
Rui-ting Hu, Qian Yu, Shao-dan Zhou, Yi-xin Yin, Rui-guang Hu, Hai-peng Lu, Bang-li Hu   +6 more
doaj   +1 more source

Analysis of multiple databases identifies crucial genes correlated with prognosis of hepatocellular carcinoma

Scientific Reports, 2022
Despite advancements made in the therapeutic strategies on hepatocellular carcinoma (HCC), the survival rate of HCC patient is not satisfactory enough. Therefore, there is an urgent need for the valuable prognostic biomarkers in HCC therapy.
Zhifeng Lin, Xuqiong Huang, Xiaohui Ji, Nana Tian, Yu Gan, Li Ke   +5 more
doaj   +1 more source

Integrative single-cell RNA sequencing and metabolomics decipher the imbalanced lipid-metabolism in maladaptive immune responses during sepsis

Frontiers in Immunology, 2023
BackgroundTo identify differentially expressed lipid metabolism-related genes (DE-LMRGs) responsible for immune dysfunction in sepsis.MethodsThe lipid metabolism-related hub genes were screened using machine learning algorithms, and the immune cell ...
Han She, Han She, Lei Tan, Lei Tan, Yi Wang, Yi Wang, Yuanlin Du, Yuanqun Zhou, Jun Zhang, Yunxia Du, Yunxia Du, Ningke Guo, Zhengbin Wu, Qinghui Li, Daiqin Bao, Qingxiang Mao, Yi Hu, Liangming Liu, Tao Li   +18 more
doaj   +1 more source

Exploration of the hub genes and miRNAs in lung adenocarcinoma

Oncology Letters, 2019
In order to investigate the oncogenic mechanisms of lung adenocarcinoma (LUAD), hub genes can be identified by constructing co-expression networks, and the potential linkages between hub genes, transcription factors (TFs) and microRNAs (miRNAs/miRs) can be visualized and identified.
Zhai, Yuanyuan, Chen, Yingli, Li, Qianzhong, Zhang, Luqiang   +3 more
openaire   +3 more sources

Enhanced construction of gene regulatory networks using hub gene information [PDF]

BMC Bioinformatics, 2017
Gene regulatory networks reveal how genes work together to carry out their biological functions. Reconstructions of gene networks from gene expression data greatly facilitate our understanding of underlying biological mechanisms and provide new opportunities for biomarker and drug discoveries.
Donghyeon Yu, Johan Lim, Xinlei Wang 0001, Faming Liang, Guanghua Xiao   +4 more
openaire   +2 more sources

Hub genes and their key effects on prognosis of Burkitt lymphoma

World Journal of Clinical Oncology, 2023
Burkitt lymphoma (BL) is an exceptionally aggressive malignant neoplasm that arises from either the germinal center or post-germinal center B cells. Patients with BL often present with rapid tumor growth and require high-intensity multi-drug therapy combined with adequate intrathecal chemotherapy prophylaxis, however, a standard treatment program for ...
Xu, Yan-Feng, Wang, Guan-Yun, Zhang, Ming-Yu, Yang, Ji-Gang   +3 more
openaire   +2 more sources