Results 51 to 60 of about 8,236,393 (357)

Clinical relevance of hub genes.

, 2022
(A) K-M curves of hub genes expression. (B) Box plots of hub genes expression and clinical variables.
Yi Zhao (14034), Helin Feng (452510), Jiazheng Zhao (11902284), Xiaowei Ma (113432), Rongmin Cui (11902287)   +4 more
core   +1 more source

Identification and validation of hub genes and potential drugs involved in osteoarthritis through bioinformatics analysis

Frontiers in Genetics, 2023
Purpose: Osteoarthritis (OA) is a common degenerative disease, which still lacks specific therapeutic drugs. Synovitis is one of the most important pathological process in OA.
Wenbo Xu, Xuyao Wang, Dong-Hui Liu, Xin Lin, Bo Wang, Chun-Yang Xi, Peng-Yu Kong, Jing Yan   +7 more
semanticscholar   +1 more source

Comprehensive analysis and validation of novel immune and vascular remodeling related genes signature associated with drug interactions in pulmonary arterial hypertension

Frontiers in Genetics, 2022
Background: Previous studies revealed that the gene signatures are associated with the modulation and pathogenesis of pulmonary arterial hypertension (PAH).
Jie Wang, Md. Nazim Uddin, Rui Wang, Yue-hong Gong, Yun Wu   +4 more
doaj   +1 more source

Identification of novel immune subtypes and potential hub genes of patients with psoriasis

Journal of Translational Medicine, 2023
Background Psoriasis is a common, chronic and relapsing immune-related inflammatory dermal disease. Patients with psoriasis suffering from the recurrences is mainly caused by immune response disorder.
Ying-Xi Li, Lin Li, Yao Tian, Jing Luo, Jun-Kai Huang, Li-Tao Zhang, Jun-Ling Zhang, Xiao-Xia Li, Li-Zhi Hu   +8 more
semanticscholar   +1 more source

Diagnostic models and predictive drugs associated with cuproptosis hub genes in Alzheimer's disease

Frontiers in Neurology, 2023
Alzheimer's disease (AD) is a chronic neurodegenerative disease, and its underlying genes and treatments are unclear. Abnormalities in copper metabolism can prevent the clearance of β-amyloid peptides and promote the progression of AD pathogenesis ...
Erdong Zhang, Feng-Qiu Dai, Tingting Chen, Shan-Hui Liu, Chao-Lun Xiao, Xiang-Chun Shen   +5 more
semanticscholar   +1 more source

united-manufacturing-hub/united-manufacturing-hub: v0.9.6

, 2022
Tldr ⚠⚠⚠ ⚠⚠⚠ this is a test regarding permissions, please disregard this release for any kind of productive use ⚠⚠⚠ What's Changed build(deps): bump github.com/minio/minio-go/v7 from 7.0.29 to 7.0.34 in /golang by @dependabot in https://github.com ...
kruegeralex, Matteo Danelon, Ferdinand Linnenberg, JonaVo, PLC-Mercenary, Robert Feldmann, Lukas Hennies, ONUR CAN KARAMAN, larswitte, Matthew Judijanto, Pascal Bro, AMINE AMAACH, Derek Tiffany, Arne, Patrick Melichar, chrisproch, felixmhofmann, Jeremy Theocharis   +17 more
core   +1 more source

Network analysis based on TCGA reveals hub genes in colon cancer [PDF]

, 2017
Colorectal cancer (CRC) is the third most widespread cancer in the world. Although many advances have been made in molecular biology, novel approaches are still required to reveal molecular mechanisms for the diagnosis and therapy of colon cancer.
Junjie Chen, Chengzu Wang, Fenzan Wu, Guoping Yuan   +3 more
core   +1 more source

ComHub: Community predictions of hubs in gene regulatory networks [PDF]

BMC Bioinformatics, 2019
Abstract Summary Hub transcription factors, regulating many target genes in gene regulatory networks (GRNs), play important roles as disease regulators and potential drug targets. However, while numerous methods have been developed to predict individual regulator-gene interactions from gene ...
Åkesson, Julia, Lubovac-Pilav, Zelmina, Magnusson, Rasmus, Gustafsson, Mika   +3 more
openaire   +6 more sources

Identification of hub genes and pathways in lung metastatic colorectal cancer

BMC Cancer, 2023
Background Colorectal cancer (CRC) is one of the most prevalent types of malignant tumours. Metastasis is the leading cause of cancer-related mortality, with lung metastases accounting for 32.9% of all metastatic CRCs.
W. Dai, Cai-Yao Guo, Yu Wang, Yumei Li, Ren-Jian Xie, Junhong Wu, Bao Yao, D. Xie, Ling He, Ying-Ying Li, Hao Huang, Yun Wang, Sheng-Lan Liu   +12 more
semanticscholar   +1 more source

ROC curves of 10 hub genes.

, 2023
(A) Diagnostic value of hub genes in the GSE5281 dataset. (B) Diagnostic value of hub genes in the GSE48350 dataset.
Pengyun Ni (16792759), Bingbing Zhao (3589415), Kaiting Pan (16792762)   +2 more
core   +1 more source