Results 31 to 40 of about 198,026 (297)
Computational methods in cancer gene networking [PDF]
, 2008 In the past few years, many high-throughput techniques have been developed and applied to biological studies. These techniques such as “next generation” genome sequencing, chip-on-chip, microarray and so on can be used to measure gene ...
Edwin Wang
core +2 more sources
ComHub: Community predictions of hubs in gene regulatory networks [PDF]
BMC Bioinformatics, 2019 AbstractSummaryHub transcription factors, regulating many target genes in gene regulatory networks (GRNs), play important roles as disease regulators and potential drug targets. However, while numerous methods have been developed to predict individual regulator-gene interactions from gene expression data, few methods focus on inferring these hubs.
Åkesson, Julia +3 more
openaire +6 more sources
Psoriasis Associated Hub Genes Revealed by Weighted Gene Co-Expression Network Analysis.
Cell journal, 2023 Psoriasis, an immune-mediated disorder, is a multifactorial disease with unidentified cause(s). This study aimed to discover possible biomarkers of this papulosquamous skin disease.The gene chip GSE55201, resulted from an experimental study, including 44 Psoriasis patients and 30 healthy controls was downloaded from GEO and weighted gene co-expression ...
Darvish, Zeinab +4 more
openaire +3 more sources
Frontiers in Genetics, 2020 Hepatocellular carcinoma (HCC) remains hard to diagnose early and cure due to a lack of accurate biomarkers and effective treatments. Hence, it is necessary to explore the tumorigenesis and tumor progression of HCC to discover new biomarkers for clinical
Yang Gu +8 more
doaj +1 more source
SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson. [PDF]
, 2016 Parkinson's disease (PD) is one of the most common neurodegenerative disorders. A theoretical approach of our previous experiments reporting the cytoprotective effects of the Valeriana officinalis compounds extract for PD is suggested.
Andrade, Bruno +7 more
core +4 more sources
Analytical Cellular Pathology, 2022 Background. To investigate the relationship between primary ovarian insufficiency and autophagy, we detected and got the expression profile of human granulosa cell line SVOG, which was with or without LPS induced. The expression profile was analyzed with
Siji Lv, Jiani Sun, Jing Sun
doaj +1 more source
LongGeneDB: a data hub for long genes [PDF]
, 2020 ABSTRACTThe human genome contains more than 4000 genes that are longer than 100 kb. These long genes require more time and resources to make a transcript than shorter genes do. Long genes have also been linked to various human diseases. Specific mechanisms are utilized by long genes to facilitate their transcription and co-transcriptional processes ...
Sohyun Moon +3 more
openaire +1 more source
Hub Genes Associated with the Diagnosis of Diabetic Retinopathy
International Journal of General Medicine, 2021 This study aimed to identify genes that may be effective in diagnosing or treating diabetic retinopathy (DR), the most common complication of diabetes mellitus (DM).Differentially expressed genes (DEGs) were identified between DR and DM in GSE146615 dataset.
Yanhui Tang +6 more
openaire +5 more sources
BMC Pediatrics, 2022 Background Infantile hemangioma (IH) is the most common benign tumor in children and is characterized by endothelial cells proliferation and angiogenesis. Some hub genes may play a critical role in angiogenesis. This study aimed to identify the hub genes
Bin Xie, Xiongming Zhou, Jiaxuan Qiu
doaj +1 more source
Heliyon, 2023 Colorectal cancer (CRC) is the third most diagnosed malignancy and the second leading cause of cancer death. The objective was to identify novel hub genes that were helpful for prognosis and targeted therapy in CRC. GSE23878, GSE24514, GSE41657, GSE81582
Min Guo, Xiaxi Li, Jiong Li, Baolong Li
doaj +1 more source