Results 31 to 40 of about 8,236,393 (357)

Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue

open access: yesFrontiers in Cellular Neuroscience, 2023
Human induced pluripotent stem cells (hiPSCs) have been used extensively in vitro to model early events in neurodevelopment. Because of a number of shortcomings, previous work has established a potential to use these cells in vivo after transplantation ...
Célia Raïs   +11 more
doaj   +1 more source

Bioinformatics and pathway enrichment analysis identified hub genes and potential biomarker for gastric cancer prognosis

open access: yesFrontiers in Oncology, 2023
Introduction Gastric cancer is one of the most common cancers in the world. This study aimed to identify genes, biomarkers, and metabolic pathways affecting gastric cancer using bioinformatic analysis and meta-analysis.
E. Darang   +3 more
semanticscholar   +1 more source

Genes-TFs interaction network.

open access: yes, 2022
Hexagons represent hub genes; circle nodes represent TFs associated with hub genes.
Yun Chen (279569)   +5 more
core   +1 more source

TGF-Beta Induced Key Genes of Osteogenic and Adipogenic Differentiation in Human Mesenchymal Stem Cells and MiRNA–mRNA Regulatory Networks

open access: yesFrontiers in Genetics, 2021
Background: The clinical efficacy of osteoporosis therapy is unsatisfactory. However, there is currently no gold standard for the treatment of osteoporosis.
Genfa Du   +6 more
doaj   +1 more source

Identification of hub genes involved in cisplatin resistance in head and neck cancer

open access: yesJournal of Genetic Engineering and Biotechnology, 2023
Cisplatin resistance is one of the major contributors to the poor survival rate among head and neck cancer (HNC) patients. Focusing on the protein–protein interaction rather than a single protein could provide a better understanding of drug resistance ...
R. Chaudhary   +4 more
semanticscholar   +1 more source

Seven key hub genes identified by gene co-expression network in cutaneous squamous cell carcinoma

open access: yesBMC Cancer, 2021
Background Cutaneous squamous cell carcinoma (cSCC) often follows actinic keratosis (AK) and is the second most common skin cancer worldwide. To reduce metastasis risk, it is important to diagnose and treat cSCC early.
Huizhen Chen, Jiankang Yang, Wenjuan Wu
doaj   +1 more source

Identification and verification of hub genes associated with ferroptosis in ischemia and reperfusion injury during renal transplantation.

open access: yesInternational Immunopharmacology, 2023
Ferroptosis is involved in ischemia and reperfusion injury (IRI) of transplanted kidney. Understanding the molecular mechanisms of ferroptosis is essential to elucidate the pathogenesis of IRI.
Qi-wu Tang   +3 more
semanticscholar   +1 more source

Analysis of hub genes in different subnetworks.

open access: yes, 2022
(A) Hub genes in Common-P. (B) Hub genes in HMI-MMI-SP. (C) Hub genes in MMI-MHCI-SP. (D) Hub genes in HMI-MHCI-SP. (E) Hub genes in HMI-SP. (F) Hub genes in MMI-SP. (G) Hub genes in MHCI-SP.
Yao Jiang (1469614)   +2 more
core   +1 more source

Bioinformatic analysis of potential hub genes in gastric adenocarcinoma [PDF]

open access: yesScience Progress, 2021
Gastric adenocarcinoma is the most common histologic type of gastric cancer; however, the pathogenic mechanisms remain unclear. To improve mechanistic understanding and identify new treatment targets or diagnostic biomarkers, we used bioinformatic tools to predict the hub genes related to the process of gastric adenocarcinoma development from public ...
Hao Liu   +5 more
openaire   +2 more sources

Identification of Ten Core Hub Genes as Potential Biomarkers and Treatment Target for Hepatoblastoma

open access: yesFrontiers in Oncology, 2021
BackgroundThis study aimed to systematically investigate gene signatures for hepatoblastoma (HB) and identify potential biomarkers for its diagnosis and treatment.Materials and MethodsGSE131329 and GSE81928 were obtained from the Gene Expression Omnibus (
Rui Sun   +5 more
doaj   +1 more source

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