Results 11 to 20 of about 8,236,393 (357)

Bioinformatics analysis of hub genes as osteoarthritis prognostic biomarkers

Scientific Reports, 2023
Osteoarthritis (OA) is a progressive cartilage degradation disease, concomitant with synovitis, osteophyte formation, and subchondral bone sclerosis.
Jun-Feng Zeng, Xin Jiang, Mo Jiang, Yue Cao, Yi Jiang   +4 more
semanticscholar   +4 more sources

Identification of Immune-Related Hub Genes in Parkinson’s Disease

Frontiers in Genetics, 2022
Background: Parkinson’s disease (PD) is a common, age-related, and progressive neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an essential role in the pathogenic process of PD.
Lin Chen, Yong Wang, Juan Huang, Binbin Hu, Wei Huang   +4 more
semanticscholar   +4 more sources

Identification of the Hub Genes in Alzheimer’s Disease [PDF]

Computational and Mathematical Methods in Medicine, 2021
Purpose. Alzheimer’s disease (AD) is considered to be the most common neurodegenerative disease and also one of the major fatal diseases affecting the elderly, thus bringing a huge burden to society. Therefore, identifying AD-related hub genes is extremely important for developing novel strategies against AD. Materials and Methods.
Huiwen Gui, Qi Gong, Jun Jiang, Mei Liu, Huanyin Li   +4 more
openaire   +2 more sources

Meta-Data Analysis to Explore the Hub of the Hub-Genes That Influence SARS-CoV-2 Infections Highlighting Their Pathogenetic Processes and Drugs Repurposing [PDF]

, 2022
The pandemic of SARS-CoV-2 infections is a severe threat to human life and the world economic condition. Although vaccination has reduced the outspread, but still the situation is not under control because of the instability of RNA sequence patterns of ...
Gow, Jeff, Khorshed Alam, Alam, Khorshed, Md. Bayazid Hossen, Gow, Jeffrey, Md. Kaderi Kibria, Md. Selim Reza, Reza, Md. Selim, Jeff Gow, Mahumud, Rashidul Alam, Kibria, Md. Kaderi, Md. Parvez Mosharaf, Rashidul Alam Mahumud, Md. Nurul Haque Mollah, Md. Ariful Islam, Mosharaf, Md. Parvez, Hossen, Md. Bayazid, Islam, Md. Ariful, Mollah, Md. Nurul Haque   +18 more
core   +1 more source

Prediction and analysis of osteoarthritis hub genes with bioinformatics

Annals of Translational Medicine, 2023
Osteoarthritis (OA) is the most common type of arthritis. OA can cause joint pain, stiffness, and loss of function. The pathogenesis of OA is not completely clear. Moreover, there is no effective treatment, and clinical management is limited to symptomatic relief or joint surgery.
Zhong, Junqing, Xiang, Ding, Ma, Xinlong
openaire   +2 more sources

Identification and validation of hub genes for diabetic retinopathy

PeerJ, 2021
Background Diabetic retinopathy (DR) is characterized by a gradually progressive alteration in the retinal microvasculature that leads to middle-aged adult acquired persistent blindness. Limited research has been conducted on DR pathogenesis at the gene level.
Peng, Li, Ma, Wei, Xie, Qing, Chen, Baihua   +3 more
openaire   +3 more sources

Hub Genes Associated with the Diagnosis of Diabetic Retinopathy

International Journal of General Medicine, 2021
This study aimed to identify genes that may be effective in diagnosing or treating diabetic retinopathy (DR), the most common complication of diabetes mellitus (DM).Differentially expressed genes (DEGs) were identified between DR and DM in GSE146615 dataset.
Yanhui Tang, Qi Tang, Haicheng Wei, Pinzhang Hu, Donghua Zou, Rixiong Liang, Yu Ling   +6 more
openaire   +5 more sources

Identification of hub genes related to prognosis in glioma [PDF]

Bioscience Reports, 2020
Abstract Glioma, a common malignant tumor of the central nervous system, has high invasiveness. The objective of the present study was to identify genes playing an important role in the development of glioma and to reveal their potential research value.
Delong Zhang, Jinxia Zhao, Chengzheng Han, Xiaocen Liu, Jun Liu, Hui Yang   +5 more
openaire   +2 more sources

Identification of potential hub genes of gastric cancer

Medicine, 2022
Abstract Background Gastric cancer (GC) is a malignant tumor originated from gastric mucosa epithelium. It is the third leading cause of cancer mortality in China. The early symptoms are not obvious. When it is discovered, it has developed to the advanced stage, and the prognosis is poor.
Xu-Dong Zhou, Ya-Wei Qu, Li Wang, Fu-Hua Jia, Peng Chen, Yin-Pu Wang, Hai-Feng Liu   +6 more
openaire   +2 more sources

Screening of potential hub genes in pulmonary thromboembolism

Experimental and Therapeutic Medicine, 2021
Pulmonary thromboembolism (PTE) is a fatal clinical syndrome that usually occurs in elderly individuals. The present study aimed to identify functional and key genes involved in the early diagnosis of PTE using bioinformatics analysis. The GSE84738 dataset was retrieved from the Gene Expression Omnibus database.
Lu, Yan, Dai, Jun, Liu, Qiyang, Cai, Pan, Zheng, Jianghua   +4 more
openaire   +3 more sources