Results 11 to 20 of about 5,790,030 (310)
Identification of the Hub Genes in Alzheimer’s Disease [PDF]
Computational and Mathematical Methods in Medicine, 2021 Purpose. Alzheimer’s disease (AD) is considered to be the most common neurodegenerative disease and also one of the major fatal diseases affecting the elderly, thus bringing a huge burden to society. Therefore, identifying AD-related hub genes is extremely important for developing novel strategies against AD. Materials and Methods.
Huiwen Gui +4 more
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Prediction and analysis of osteoarthritis hub genes with bioinformatics
Annals of Translational Medicine, 2023 Osteoarthritis (OA) is the most common type of arthritis. OA can cause joint pain, stiffness, and loss of function. The pathogenesis of OA is not completely clear. Moreover, there is no effective treatment, and clinical management is limited to symptomatic relief or joint surgery.
Zhong, Junqing, Xiang, Ding, Ma, Xinlong
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Identification and validation of hub genes for diabetic retinopathy
PeerJ, 2021 Background Diabetic retinopathy (DR) is characterized by a gradually progressive alteration in the retinal microvasculature that leads to middle-aged adult acquired persistent blindness. Limited research has been conducted on DR pathogenesis at the gene level.
Peng, Li +3 more
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Hub Genes Associated with the Diagnosis of Diabetic Retinopathy
International Journal of General Medicine, 2021 This study aimed to identify genes that may be effective in diagnosing or treating diabetic retinopathy (DR), the most common complication of diabetes mellitus (DM).Differentially expressed genes (DEGs) were identified between DR and DM in GSE146615 dataset.
Yanhui Tang +6 more
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Frontiers in Neuroscience, 2023 Objective Neuropathic pain as a complex chronic disease that occurs after neurological injury, however the underlying mechanisms are not clarified in detail, hence therapeutic options are limited.
Jianfeng Zeng +3 more
semanticscholar +1 more source
Scientific Reports, 2023 Alzheimer’s disease (AD) is the leading cause of dementia in aged population. Oxidative stress and neuroinflammation play important roles in the pathogenesis of AD.
Shengjie Li +3 more
semanticscholar +1 more source
Identification of potential hub genes of gastric cancer
Medicine, 2022 Abstract Background Gastric cancer (GC) is a malignant tumor originated from gastric mucosa epithelium. It is the third leading cause of cancer mortality in China. The early symptoms are not obvious. When it is discovered, it has developed to the advanced stage, and the prognosis is poor.
Xu-Dong Zhou +6 more
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Identification and Validation of Hub Genes in Hidradenitis Suppurativa. [PDF]
Clin Cosmet Investig DermatolHidradenitis suppurativa (HS) is a severe, chronic inflammatory disease characterized by inflammatory nodules, progressive sinus tracts, and fistulas. Currently, its pathogenesis remain incompletely understood, and while diverse treatments are available, these have suboptimal efficacy.
Zhai YN +8 more
europepmc +4 more sources
Applied Sciences, 2023 Breast cancer (BC) is the most incident cancer type among women. BC is also ranked as the second leading cause of death among all cancer types. Therefore, early detection and prediction of BC are significant for prognosis and in determining the suitable ...
M. Elbashir +3 more
semanticscholar +1 more source
Screening of potential hub genes in pulmonary thromboembolism
Experimental and Therapeutic Medicine, 2021 Pulmonary thromboembolism (PTE) is a fatal clinical syndrome that usually occurs in elderly individuals. The present study aimed to identify functional and key genes involved in the early diagnosis of PTE using bioinformatics analysis. The GSE84738 dataset was retrieved from the Gene Expression Omnibus database.
Lu, Yan +4 more
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