Results 21 to 30 of about 5,790,030 (310)
Identification of hub genes related to prognosis in glioma [PDF]
Bioscience Reports, 2020 Abstract Glioma, a common malignant tumor of the central nervous system, has high invasiveness. The objective of the present study was to identify genes playing an important role in the development of glioma and to reveal their potential research value.
Delong Zhang +5 more
openaire +2 more sources
Scientific Reports, 2023 Hepatocellular carcinoma (HCC) is the most common lethal malignancy of the liver worldwide. Thus, it is important to dig the key genes for uncovering the molecular mechanisms and to improve diagnostic and therapeutic options for HCC.
M. Hasan, Md. Maniruzzaman, Jungpil Shin
semanticscholar +1 more source
Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation [PDF]
PeerJ, 2022 Background The mechanism of immunoglobulin A nephropathy (IgAN) is still unknown. A bioinformatics analysis is a powerful method to identify the biomarkers and possible therapeutic targets of a certain disease from related datasets.
Wu Jianping +5 more
doaj +2 more sources
Endocrine Disrupting Chemicals Influence Hub Genes Associated with Aggressive Prostate Cancer
International Journal of Molecular Sciences, 2023 Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men in the world. Its prevention has been limited because of an incomplete understanding of how environmental exposures to chemicals contribute to the molecular pathogenesis of ...
Diaaidden Alwadi +4 more
semanticscholar +1 more source
BMC Medical Genomics, 2023 Background Dendritic cells (DCs) are most potent antigen-processing cells and play key roles in host defense against Mycobacterium tuberculosis (MTB) infection.
Xiao Wu +9 more
doaj +1 more source
Identification of hub genes involved in cisplatin resistance in head and neck cancer
Journal of Genetic Engineering and Biotechnology, 2023 Cisplatin resistance is one of the major contributors to the poor survival rate among head and neck cancer (HNC) patients. Focusing on the protein–protein interaction rather than a single protein could provide a better understanding of drug resistance ...
R. K. Chaudhary +4 more
semanticscholar +1 more source
Identification and validation of ferroptosis-related hub genes in obstructive sleep apnea syndrome
Frontiers in Neurology, 2023 Background By 2020, the prevalence of Obstructive Sleep Apnea Syndrome (OSAS) in the US has reached 26. 6–43.2% in men and 8.7–27.8% in women. OSAS promotes hypertension, diabetes, and tumor growth through unknown means. Chronic intermittent hypoxia (CIH)
Peijun Liu +5 more
semanticscholar +1 more source
Diagnostic models and predictive drugs associated with cuproptosis hub genes in Alzheimer's disease
Frontiers in Neurology, 2023 Alzheimer's disease (AD) is a chronic neurodegenerative disease, and its underlying genes and treatments are unclear. Abnormalities in copper metabolism can prevent the clearance of β-amyloid peptides and promote the progression of AD pathogenesis ...
Erdong Zhang +5 more
semanticscholar +1 more source
Frontiers in Genetics, 2021 Background: The clinical efficacy of osteoporosis therapy is unsatisfactory. However, there is currently no gold standard for the treatment of osteoporosis.
Genfa Du +6 more
doaj +1 more source
International Immunopharmacology, 2023 Ferroptosis is involved in ischemia and reperfusion injury (IRI) of transplanted kidney. Understanding the molecular mechanisms of ferroptosis is essential to elucidate the pathogenesis of IRI.
Qi-wu Tang +3 more
semanticscholar +1 more source