Results 21 to 30 of about 8,236,393 (357)
Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation [PDF]
PeerJ, 2022 Background The mechanism of immunoglobulin A nephropathy (IgAN) is still unknown. A bioinformatics analysis is a powerful method to identify the biomarkers and possible therapeutic targets of a certain disease from related datasets.
Wu Jianping +5 more
doaj +2 more sources
Applied Sciences, 2023 Breast cancer (BC) is the most incident cancer type among women. BC is also ranked as the second leading cause of death among all cancer types. Therefore, early detection and prediction of BC are significant for prognosis and in determining the suitable ...
M. Elbashir +3 more
semanticscholar +1 more source
Clinical Values of the Identified Hub Genes in Systemic Lupus Erythematosus
Frontiers in Immunology, 2022 ObjectiveThis study was conducted to identify the biomarkers and mechanisms associated with systemic lupus erythematosus(SLE) at a transcriptome level.MethodsMicroarray datasets were downloaded, and differentially expressed genes (DEGs) were identified ...
Lu Xiao, Feng Zhan, Shudian Lin
doaj +1 more source
WGCNA Analysis Identifies the Hub Genes Related to Heat Stress in Seedling of Rice (Oryza sativa L.)
Genes, 2022 Frequent high temperature weather affects the growth and development of rice, resulting in the decline of seed–setting rate, deterioration of rice quality and reduction of yield.
Yu-Bo Wang +7 more
semanticscholar +1 more source
BMC Medical Genomics, 2023 Background Dendritic cells (DCs) are most potent antigen-processing cells and play key roles in host defense against Mycobacterium tuberculosis (MTB) infection.
Xiao Wu +9 more
doaj +1 more source
Frontiers in Immunology, 2023 Background Drug-induced acute kidney damage (DI-AKI) is a clinical phenomenon of rapid loss of kidney function over a brief period of time as a consequence of the using of medicines.
Yi-Di Deng +11 more
semanticscholar +1 more source
Identification of Hub Genes With Differential Correlations in Sepsis
Frontiers in Genetics, 2022 As a multifaceted syndrome, sepsis leads to high risk of death worldwide. It is difficult to be intervened due to insufficient biomarkers and potential targets. The reason is that regulatory mechanisms during sepsis are poorly understood. In this study, expression profiles of sepsis from GSE134347 were integrated to construct gene interaction network ...
Lulu Sheng +3 more
openaire +3 more sources
Identification of hub genes associated with spermatogenesis by bioinformatics analysis
Scientific Reports, 2023 Spermatogenesis is a complex process related to male infertility. Till now, the critical genes and specific mechanisms have not been elucidated clearly. Our objective was to determine the hub genes that play a crucial role in spermatogenesis by analyzing
Shuang Liu +7 more
semanticscholar +1 more source
Endocrine Disrupting Chemicals Influence Hub Genes Associated with Aggressive Prostate Cancer
International Journal of Molecular Sciences, 2023 Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men in the world. Its prevention has been limited because of an incomplete understanding of how environmental exposures to chemicals contribute to the molecular pathogenesis of ...
Diaaidden Alwadi +4 more
semanticscholar +1 more source
Genes-miRNAs interaction network.
, 2022 Hexagons represent hub genes; circle nodes represent miRNAs associated with hub genes.
Yun Chen (279569) +5 more
core +1 more source