Results 21 to 30 of about 198,026 (297)
Seven key hub genes identified by gene co-expression network in cutaneous squamous cell carcinoma
BMC Cancer, 2021 Background Cutaneous squamous cell carcinoma (cSCC) often follows actinic keratosis (AK) and is the second most common skin cancer worldwide. To reduce metastasis risk, it is important to diagnose and treat cSCC early.
Huizhen Chen, Jiankang Yang, Wenjuan Wu
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Identification of Ten Core Hub Genes as Potential Biomarkers and Treatment Target for Hepatoblastoma
Frontiers in Oncology, 2021 BackgroundThis study aimed to systematically investigate gene signatures for hepatoblastoma (HB) and identify potential biomarkers for its diagnosis and treatment.Materials and MethodsGSE131329 and GSE81928 were obtained from the Gene Expression Omnibus (
Rui Sun +5 more
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The Nuclear Lamina as a Gene-silencing Hub [PDF]
Current Issues in Molecular Biology, 2012 There is accumulating evidence that the nuclear periphery is a transcriptionally repressive compartment. A surprisingly large fraction of the genome is either in transient or permanent contact with nuclear envelope, where the majority of genes are maintained in a silent state, waiting to be awakened during cell differentiation.
Shevelyov, Yuri Y., Nurminsky, Dmitry I.
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Text Mining and Hub Gene Network Analysis of Endometriosis [PDF]
BioMed Research International, 2021 This study is aimed at systematically characterizing the endometriosis‐associated genes based on text mining and at annotating the functions, pathways, and networks of endometriosis‐associated hub genes. We extracted endometriosis‐associated abstracts published between 1970 and 2020 from the PubMed database.
Yinuo Wang +4 more
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Frontiers in Cellular Neuroscience, 2023 Human induced pluripotent stem cells (hiPSCs) have been used extensively in vitro to model early events in neurodevelopment. Because of a number of shortcomings, previous work has established a potential to use these cells in vivo after transplantation ...
Célia Raïs +11 more
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Identification of key genes and biological pathways in Chinese lung cancer population using bioinformatics analysis [PDF]
PeerJ, 2022 Background Identification of accurate prognostic biomarkers is still particularly urgent for improving the poor survival of lung cancer patients.
Ping Liu +7 more
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Frontiers in Immunology, 2023 BackgroundDiabetic nephropathy (DN) is the primary cause of end-stage renal disease, but existing therapeutics are limited. Therefore, novel molecular pathways that contribute to DN therapy and diagnostics are urgently needed.MethodsBased on the Gene ...
Mingming Xu +6 more
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Frontiers in Physiology, 2017 Objective: To identify candidate biomarkers correlated with clinical prognosis of patients with bladder cancer (BC).Methods: Weighted gene co-expression network analysis was applied to build a co-expression network to identify hub genes correlated with ...
Sheng Li +14 more
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Frontiers in Genetics, 2022 Background: Previous studies revealed that the gene signatures are associated with the modulation and pathogenesis of pulmonary arterial hypertension (PAH).
Jie Wang +4 more
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cis-regulatory circuits regulating NEK6 kinase overexpression in transformed B cells Are super-enhancer independent [PDF]
, 2017 Alterations in distal regulatory elements that control gene expression underlie many diseases, including cancer. Epigenomic analyses of normal and diseased cells have produced correlative predictions for connections between dysregulated enhancers and ...
Huang, Yue +6 more
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