Results 131 to 140 of about 8,236,393 (357)

Hub microRNAs and genes in the development of atrial fibrillation identified by weighted gene co-expression network analysis

BMC Medical Genomics, 2021
Co-expression network may contribute to better understanding molecular interaction patterns underlying cellular processes. To explore microRNAs (miRNAs) expression patterns correlated with AF, we performed weighted gene co-expression network analysis ...
Qiang Qu, Jin-Yu Sun, Zhen-Ye Zhang, Yue Su, Shan-Shan Li, Feng Li, Ru-Xing Wang   +6 more
doaj   +1 more source

Integrated Bioinformatics-Based Analysis of Hub Genes and the Mechanism of Immune Infiltration Associated With Acute Myocardial Infarction

Frontiers in Cardiovascular Medicine, 2022
Background Acute myocardial infarction (AMI) is a fatal disease that causes high morbidity and mortality. It has been reported that AMI is associated with immune cell infiltration.
Yan-Ze Wu, Ting Jiang, Jing-Hai Hua, Zhiping Xiong, Hui Chen, Lei Li, Jing-Wen Peng, Wen-Jun Xiong   +7 more
semanticscholar   +1 more source

Top 20 of hub genes.

, 2019
Network 3 predicted Hub genes and their homologs.
Antonio Luna-González (741087), José Luis Juárez-Morales (7224188), Ilie S. Racotta (7224191), Norma Estrada (7224203), Oswaldo Valdes-Lopez (7224197), Humberto Villarreal-Colmenares (7224194), Carmen Rodríguez-Jaramillo (7224200), Felipe Ascencio (7224206), Adrián E. Velázquez-Lizárraga (7224185)   +8 more
core   +1 more source

Hub genes identified through PPI analysis.

, 2022
Hub genes identified through PPI analysis.
Yun Chen (279569), Ying Zhao (16546), Chenyun Miao (10668003), Xiaojie Fang (8319717), Qin Zhang (58638), Ruye Wang (3986681)   +5 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Linking Disulfide Levels and NAD+ Metabolism with Alzheimer’s Disease for Diagnostic Modeling and Target Drug Analysis

Journal of Integrative Neuroscience
Background: Alzheimer’s disease (AD) is a condition that affects the nervous system and that requires considerably more in-depth study. Abnormal Nicotinamide Adenine Dinucleotide (NAD+) metabolism and disulfide levels have been demonstrated in AD.
Yanbing Wang, Lining Su, Yongcai Zhang, Huiping Wei   +3 more
doaj   +1 more source

Comparative physiological and transcriptomic analyses reveal key regulatory networks and potential hub genes controlling peanut chilling tolerance.

Genomics, 2022
The unclear molecular mechanism by which peanuts adapt to chilling stress limits progress in molecular breeding for peanut chilling tolerance. Here, the physiological and transcriptional differences between two genotypes with contrasting tolerance under ...
He Zhang, Chun-Ji Jiang, Jingna Lei, Jiale Dong, Jing-Yao Ren, Xiaolong Shi, C. Zhong, Xiao-Guang Wang, Xin-Hua Zhao, Hai-Qiu Yu   +9 more
semanticscholar   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Identification of Ferroptosis-Related Hub Genes and Their Association with Immune Infiltration in Chronic Obstructive Pulmonary Disease by Bioinformatics Analysis

International Journal of COPD, 2022
Purpose Ferroptosis and immune infiltration are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). We aim to identify ferroptosis-related hub genes and analyze their association with immune infiltration in COPD through ...
Yican Yang, Mengyu Zhang, Jianyu Liu, Yuan-Yuan Jiang, Xiu-Li Ji, Yi-Qing Qu   +5 more
semanticscholar   +1 more source

Identification of hub genes from PPI network.

, 2022
Identification of hub genes from PPI network.
Chunhua Xiang (11442440), Shiyuan Huang (10898622), Yi Song (105202)   +2 more
core   +1 more source