Results 101 to 110 of about 1,230,484 (264)

A pilot randomized controlled trial to examine the impact of a therapy dog intervention on loneliness in adult patients hospitalized in a psychiatric unit

open access: yesFrontiers in Psychiatry
Background and objectivesLoneliness has been linked to a number of health threats and is associated with significant morbidity and mortality risks among people with mental illness.
Nancy R. Gee   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Host Immune Response to Bovine Viral Diarrhea Virus (BVDV): Insights and Strategies for Effective Vaccine Design

open access: yesVaccines
Bovine viral diarrhea (BVD) is caused by bovine viral diarrhea virus (BVDV), a member of the genus Pestivirus and in the family Flaviviridae. According to some studies, the disease incurs USD 1.5–2.5 billion per year and USD 0.50 to USD 687.80 per cow ...
Asamenew Tesfaye Melkamsew   +2 more
doaj   +1 more source

Human-Animal Interaction in Post-Tsunami Japan

open access: yesHumanimalia, 2016
This paper explores the interaction between humans and their companion animals after the large tsunami which hit the northeast coast of Japan on 11 March 2011.
Hazuki Kajiwara
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Animal-computer interaction: advances and opportunities [PDF]

open access: yes
We are excited to present this Special Issue, which shares new ideas and developments in the field of Animal–Computer Interaction, including those that advance scientific knowledge about animals, enhance connections between species, improve the ...
French, Fiona
core  

Exploring adolescents’ attitudes and animal ethics orientations in a socio-scientific issues context: insights from a study on animal experimentation

open access: yesDiscover Education
Teaching socio-scientific issues (SSI) fosters students' ethical reasoning, yet many educators struggle with integrating these topics into science classrooms. This exploratory mixed-methods study investigates how ethical reflection influences adolescents'
Sonja Michaela Enzinger-Mühlbacher   +1 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy